Abstract: A wearable fluid delivery device (FDD) has a fluidic module and an electromechanical module. The fluidic module has a fluid path from a fluid reservoir to an outlet to a patient that is separate from the electromechanical module and its components that control the delivery of the fluid to the patient. A pump that can be disposed in the fluidic module, or in the electromechanical module and external to the fluid path. The FDD can have a releasably coupled first housing and second housing that enclose a respective one of the fluidic module and the electromechanical module. The first and second housings when connected have respective ones of aligned sensor opening and sensor access opening to create a sensor access area and permit a sensor to detect a pressure in the fluid path and thereby provide a pressure sensing system external to the fluid path.

Abstract: An improved system and method for testing fluid delivery devices is provided. The system comprises a volumetric flow rate sensor and a pressure sensor in fluid communication with the volumetric flow rate sensor. A flow restrictor is provided downstream of the flow rate and pressure sensors. A pressure regulator controls back pressure to a collection reservoir. A processor receives flow rate signals from the volumetric flow rate sensor and pressure signals from the pressure sensors and stores the flow rate signal values and pressure signal values in a memory of the testing system.

Abstract: A drug delivery investigation device includes a needle insertion mechanism having a cannula, a flow path having an inlet configured to be in fluid communication with a fluid source and an outlet, connection tubing extending between the outlet of the flow path and the needle insertion mechanism, with the connection tubing in fluid communication with the cannula and the flow path, a flow sensor positioned between the inlet and the outlet of the flow path, and a pressure sensor positioned between the inlet and the outlet of the flow path.

Abstract: A needle hub for a drug delivery device includes a needle holder and a needle attached to the needle holder, a needle actuation assembly configured to move the needle holder from a retracted position, to an insertion position, and back to the retracted position, and a pressure interlock comprising an inlet configured to be in fluid communication with a fluid source, an outlet in fluid communication with the needle, and a lock member. The lock member having a first position where the lock member prevents actuation of the needle actuation assembly and a second position where the lock member allows actuation of the needle actuation assembly. The lock member is moved from the first position to the second position based on a pressure within the pressure interlock.

Abstract: Capillary-based pressure threshold sensors are provided for liquids that exploit the properties of hydrophobic, superhydrophobic, oleophobic and amphiphobic porous membranes to detect when fluid passes through the membrane in the event of the pressure across the membrane rising above the breakthrough pressure of a fluid. Example implementations are provided of different configurations for a capillary-based pressure threshold sensor, and of how a capillary-based pressure threshold sensor is used in a medication delivery device or other fluid delivery devices to detect occlusion or other fluid flow condition.

Abstract: Capillary-based pressure threshold sensors are provided for liquids that exploit the properties of hydrophobic, superhydrophobic, oleophobic and amphiphobic porous membranes to detect when fluid passes through the membrane in the event of the pressure across the membrane rising above the breakthrough pressure of a fluid. Example implementations are provided of different configurations for a capillary-based pressure threshold sensor, and of how a capillary-based pressure threshold sensor is used in a medication delivery device or other fluid delivery devices to detect occlusion or other fluid flow condition.

Abstract: An insertion mechanism for a drug delivery device including a reservoir and a pump configured to deliver fluid from the reservoir includes a fluid path configured to be in fluid communication with the reservoir, an activation member in fluid communication with the fluid path, and an energy storage member connected to the activation member. The energy storage member has a stored state and a released state, where the energy storage member transitions from the stored state to the released state when fluid from the reservoir contacts the activation member.

Abstract: A drug delivery device includes a housing, a reservoir positioned within the housing and configured to receive a fluid, a fluid line in fluid communication with the reservoir, a delivery sub-system configured to deliver a fluid from the reservoir to the fluid line, an insertion mechanism including a cannula in fluid communication with the fluid line, with the insertion mechanism configured to move the cannula from a retracted position where the cannula is positioned within the housing to an extended position where at least a portion of the cannula is positioned outside of the housing, a sensor configured to detect when air is present within the fluid line, and control electronics configured to actuate the insertion mechanism based on a signal from the sensor.

Abstract: A needle hub for a drug delivery device includes a needle holder and a needle attached to the needle holder, a needle actuation assembly configured to move the needle holder from a retracted position, to an insertion position, and back to the retracted position, and a pressure interlock comprising an inlet configured to be in fluid communication with a fluid source, an outlet in fluid communication with the needle, and a lock member. The lock member having a first position where the lock member prevents actuation of the needle actuation assembly and a second position where the lock member allows actuation of the needle actuation assembly. The lock member is moved from the first position to the second position based on a pressure within the pressure interlock.

Abstract: Capillary-based pressure threshold sensors are provided for liquids that exploit the properties of hydrophobic, superhydrophobic, oleophobic and amphiphobic porous membranes to detect when fluid passes through the membrane in the event of the pressure across the membrane rising above the breakthrough pressure of a fluid. Example implementations are provided of different configurations for a capillary-based pressure threshold sensor, and of how a capillary-based pressure threshold sensor is used in a medication delivery device or other fluid delivery devices to detect occlusion or other fluid flow condition.