Abstract: A multi-piece seal preferably for a sealed joint of a fuel tank assembly. An outer member has in an uncompressed state a cross-sectional shape defined by substantially semi-circular-shaped portions that define a substantially semi-circular channel and that terminate in free ends. An inner member is disposed at least partially in the channel of the outer member and has in an uncompressed state a substantially round cross-sectional shape. Preferably, the outer member is composed of a permeation-resistant material, and the inner member is composed of a relatively less expensive material capable of better elasticity performance at relatively lower temperatures compared to the outer member. The outer member preferably has lobed ends and the inner member preferably includes one or both of a stress-relieving feature or an orientation feature to orient the inner member relative to the outer member.