Abstract: An apparatus for treating venous insufficiency is disclosed. The apparatus includes a plurality of actuator assemblies receivable on a limb of a user. The actuator assemblies include: a flexible element including a body portion and two opposing end portions. The body portion is configured to at least partly extend around an outer periphery of the limb. An actuator is coupled to the opposing end portions and configured to selectively reduce a distance between the two end portions to compress the limb.

Abstract: An apparatus for treating or preventing venous deficiency, thrombus development, orthostatic intolerance, lymphedema, and/or edema comprising a sleeve wearable on a limb of a user; an upper bracket and a lower bracket releasably couplable to the limb; an actuator coupled to one of the upper or lower brackets; a shaft coupled to the actuator and the other of the upper or lower brackets; a plurality of cams fixedly coupled to, and longitudinally spaced along, the shaft; and a respective plurality of flexible elements each coupled to one of the plurality of cams and to the sleeve. Rotational motion of the actuator about an axis of rotation causes the plurality of cams, via the respective plurality of flexible elements, to induce a peristaltic pressure wave in the limb.