Patents by Inventor Danielle K. Neff

Danielle K. Neff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thieno- and furo-pyrimidine modulators of the histamine Hreceptor
    Patent number: 8937075
    Abstract: Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: January 20, 2015
    Assignee: Janssen Pharmaceutica, NV
    Inventors: James P. Edwards, Danielle K. Neff, Deborah M. Smith, Jennifer D. Venable
  • Thieno- and furo-pyrimidine modulators of the histamine H4 receptor
    Patent number: 8927555
    Abstract: Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: January 6, 2015
    Assignee: Janssen Pharmaceutica, NV
    Inventors: James P. Edwards, Danielle K. Neff, Deborah M. Smith, Jennifer D. Venable
  • Thieno- and furo-pyrimidine modulators of the histamine Hreceptor
    Patent number: 8445482
    Abstract: Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: May 21, 2013
    Assignee: Janssen Pharmaceutica NV
    Inventors: James P. Edwards, Danielle K. Neff, Deborah M. Smith, Jennifer D. Venable
  • Thieno- and furo-pyrimidine modulators of the histamine H4 receptor
    Patent number: 8440654
    Abstract: Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
    Type: Grant
    Filed: April 25, 2012
    Date of Patent: May 14, 2013
    Assignee: Janssen Pharmaceutica NV
    Inventors: James P. Edwards, Danielle K. Neff, Deborah M. Smith, Jennifer D. Venable
  • THIENO- AND FURO-PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR
    Publication number: 20120270855
    Abstract: Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
    Type: Application
    Filed: April 25, 2012
    Publication date: October 25, 2012
    Inventors: James P. Edwards, Danielle K. Neff, Deborah M. Smith, Jennifer D. Venable
  • THIENO- ADN FURO-PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR
    Publication number: 20120214792
    Abstract: Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
    Type: Application
    Filed: April 25, 2012
    Publication date: August 23, 2012
    Inventors: James P. Edwards, Danielle K. Neff, Deborah M. Smith, Jennifer D. Venable
  • THIENO- AND FURO-PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR
    Publication number: 20120208793
    Abstract: Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
    Type: Application
    Filed: April 25, 2012
    Publication date: August 16, 2012
    Inventors: James P. Edwards, Danielle K. Neff, Deborah M. Smith, Jennifer D. Venable
  • Thieno- and furo-pyrimidine modulators of the histamine Hreceptor
    Patent number: 8193178
    Abstract: Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
    Type: Grant
    Filed: September 12, 2008
    Date of Patent: June 5, 2012
    Assignee: Janssen Pharmaceutica NV
    Inventors: James P. Edwards, Danielle K. Neff, Deborah M. Smith, Jennifer D. Venable
  • 2-AMINOPYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR
    Publication number: 20110218338
    Abstract: 2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritus.
    Type: Application
    Filed: April 11, 2011
    Publication date: September 8, 2011
    Inventors: Hui Cai, Frank Chavez, James P. Edwards, Anne E. Fitzgerald, Jing Liu, Neelakandha S. Mani, Danielle K. Neff, Michele C. Rizzolio, Brad M. Savall, Deborah M. Smith, Jennifer D. Venable, Jianmei Wei, Ronald L. Wolin
  • 2-Aminopyrimidine modulators of the histamine H4 receptor
    Publication number: 20110160452
    Abstract: 2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
    Type: Application
    Filed: March 8, 2011
    Publication date: June 30, 2011
    Inventors: Hui Cai, Frank Chavez, James P. Edwards, Anne E. Fitzgerald, Jing Liu, Neelakandha S. Mani, Danielle K. Neff, Michele C. Rizzolio, Brad M. Savall, Deborah M. Smith, Jennifer D. Venable, Jianmai Wei, Ronald L. Wolin
  • 2-Aminopyrimidine modulators of the histamine H4 receptor
    Publication number: 20110160451
    Abstract: 2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
    Type: Application
    Filed: March 8, 2011
    Publication date: June 30, 2011
    Inventors: Hui CAI, Frank CHAVEZ, James P. EDWARDS, Anne E. FITZGERALD, Jing LIU, Neelakandha S. MANI, Danielle K. NEFF, Michele C. RIZZOLIO, Brad M. SAVALL, Deborah M. SMITH, Jennifer D. VENABLE, Jianmei WEI, Ronald L. WOLIN
  • TETRAHYDRO-PYRAZOLO-PYRIDINE THIOETHER MODULATORS OF CATHEPSIN S
    Publication number: 20090099157
    Abstract: Tetrahydro-pyrazolo-pyridine thioether compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.
    Type: Application
    Filed: February 14, 2008
    Publication date: April 16, 2009
    Inventors: Michael K. Ameriks, Kristen L. Arienti, James P. Edwards, Cheryl A. Grice, Todd K. Jones, Alice Lee-Dutra, Jing Liu, Neelakandha S. Mani, Danielle K. Neff, Alvah T. Wickboldt, John J.M. Wiener
  • Thieno-and furo-pyrimidine modulators of the histamine H4 receptor
    Publication number: 20090075970
    Abstract: Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
    Type: Application
    Filed: September 12, 2008
    Publication date: March 19, 2009
    Inventors: James P. Edwards, Danielle K. Neff, Deborah M. Smith, Jennifer D. Venable
  • 2-Aminopyrimidine modulators of the histamine H4 receptor
    Publication number: 20080194577
    Abstract: 2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
    Type: Application
    Filed: February 14, 2008
    Publication date: August 14, 2008
    Inventors: Hui Cai, Frank Chavez, James P. Edwards, Anne E. Fitzgerald, Jing Liu, Neelakandha S. Mani, Danielle K. Neff, Michele C. Rizzolio, Brad M. Savall, Deborah M. Smith, Jennifer D. Venable, Jianmei Wei, Ronald L. Wolin
  • Aryl-substituted benzimidazole and imidazopyridine ethers
    Patent number: 7250427
    Abstract: Aryl substituted benzimidazole and imidazo[4,5]pyridine ethers are described as inhibitors of Cds1 and useful as adjuvants to chemotherapy or radiation therapy in the treatment of cancer.
    Type: Grant
    Filed: June 27, 2005
    Date of Patent: July 31, 2007
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: J. Guy Breitenbucher, Alice Lee-Dutra, Danielle K. Neff