Abstract: The disclosure is directed to compounds of Formula I Pharmaceutical compositions comprising compounds of Formula I, as well as methods of their use and preparation, are also described.

Abstract: In the present invention, microbial inoculants that promoted leafy green plant growth were developed using Rhodococcus erythropolis, Stenotrophomonas maltophilia, Serratia grimesii, and Pseudomonas toyotomiensis. The microbial inoculants include probiotics effective on their own and others effective in specific combinations as follows: Rhodococcus erythropolis; Rhodococcus erythropolis and Serratia grimesii; Serratia grimesii; Serratia grimesii and Pseudomonas toyotomiensis; Pseudomonas toyotomiensis and Stenotrophomonas maltophilia; Rhodococcus erythropolis, Pseudomonas toyotomiensis and Stenotrophomonas maltophilia; Rhodococcus erythropolis, Pseudomonas toyotomiensis, Stenotrophomonas maltophilia, and Serratia grimesii; Shinella zoogloeoides; and Rhodococcus erythropolis, Pseudomonas toyotomiensis, Stenotrophomonas maltophilia, Serratia grimesii and Shinella zoogloeoides.