Patents by Inventor Danilo Casimiro

Danilo Casimiro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LIPID NANOPARTICLES FOR DELIVERING mRNA VACCINES
    Publication number: 20260102349
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Application
    Filed: September 16, 2025
    Publication date: April 16, 2026
    Inventors: Danilo CASIMIRO, Sudha CHIVUKULA, Kirill KALNIN, Timothy PLITNIK, Timothy TIBBITTS, Angela Lynne BEAULIEU, Frank DEROSA, Anusha DIAS, Rebecca L. GOLDMAN, Hardip Rajeshbhai GOPANI, Shrirang KARVE, Asad KHANMOHAMMED, Natalia VARGAS MONTOYA, Priyal PATEL, Ashish L. SARODE, Khang Anh TRAN
  • Compositions for use in treatment of acne
    Patent number: 12502424
    Abstract: This invention relates to compositions (e.g. immunogenic compositions) which can be used to immunise against C. acnes. The compositions comprise C. acnes antigens and antigen combinations, used in the form of nucleic acids (e.g. mRNAs) encoding antigenic proteins or in the form of recombinant protein antigens.
    Type: Grant
    Filed: May 3, 2024
    Date of Patent: December 23, 2025
    Assignee: SANOFI PASTEUR INC.
    Inventors: Nadège Arnaud Barbe, Danilo Casimiro, Andreas Karlsson, Isabelle Legastelois, Noëlle Mistretta, Geneviève Renauld, Bachra Mohamed Rokbi, Khang Tran, Monica Wu
  • Tuberculosis Antigen Cassettes
    Publication number: 20250127869
    Abstract: The present disclosure provides fusion proteins comprising Mycobacterium tuberculosis (Mtb) antigens, nucleic acid molecules encoding the same, vectors comprising nucleic acid molecules, compositions comprising the same, and methods of eliciting an immune response against tuberculosis.
    Type: Application
    Filed: November 4, 2024
    Publication date: April 24, 2025
    Inventors: Dominick Laddy, Danilo Casimiro, Thomas Evans, Megan Fitzpatrick Forrest, Nathalie Cadieux
  • Lipid nanoparticles for delivering mRNA vaccines
    Patent number: 12239735
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Grant
    Filed: November 7, 2023
    Date of Patent: March 4, 2025
    Assignee: SANOFI
    Inventors: Danilo Casimiro, Sudha Chivukula, Kirill Kalnin, Timothy Plitnik, Timothy Tibbitts, Frank Derosa, Anusha Dias, Rebecca L. Goldman, Hardip Rajeshbhai Gopani, Shrirang Karve, Asad Khanmohammed, Priyal Patel
  • Tuberculosis antigen cassettes
    Patent number: 12168047
    Abstract: The present disclosure provides fusion proteins comprising Mycobacterium tuberculosis (Mtb) antigens, nucleic acid molecules encoding the same, vectors comprising nucleic acid molecules, compositions comprising the same, and methods of eliciting an immune response against tuberculosis.
    Type: Grant
    Filed: March 16, 2023
    Date of Patent: December 17, 2024
    Assignee: International AIDS Vaccine Initiative, Inc.
    Inventors: Dominick Laddy, Danilo Casimiro, Thomas Evans, Megan Fitzpatrick Forrest, Nathalie Cadieux
  • COMPOSITIONS FOR USE IN TREATMENT OF ACNE
    Publication number: 20240374698
    Abstract: This invention relates to compositions (e.g. immunogenic compositions) which can be used to immunise against C. acnes. The compositions comprise C. acnes antigens and antigen combinations, used in the form of nucleic acids (e.g. mRNAs) encoding antigenic proteins or in the form of recombinant protein antigens.
    Type: Application
    Filed: May 3, 2024
    Publication date: November 14, 2024
    Inventors: Nadège ARNAUD BARBE, Danilo CASIMIRO, Andreas KARLSSON, Isabelle LEGASTELOIS, Noëlle MISTRETTA, Geneviève RENAULD, Bachra MOHAMED ROKBI, Khang TRAN, Monica WU
  • OPTIMIZED NUCLEOTIDE SEQUENCES ENCODING SARS-COV-2 ANTIGENS
    Publication number: 20240342269
    Abstract: The present invention relates to optimized nucleotide sequence encoding SARS-COV-2 antigens. These sequences are particularly suitable for use in vaccine compositions for the treatment or prevention of infections caused by a ?-coronaviruses, including COVID-19 infections, in a human or animal subject in need of such treatment.
    Type: Application
    Filed: May 7, 2021
    Publication date: October 17, 2024
    Inventors: Anusha DIAS, Khang Anh TRAN, Minnie ZACHARIA, Xiaobo GU, Lianne BOEGLIN, Joseph A. SKALESKI, Shrirang KARVE, Frank DEROSA, Tong-Ming FU, Kirill KALNIN, Sudha CHIVUKULA, Timothy PLITNIK, Danilo CASIMIRO, Jeffrey S. DUBINS
  • COVID-19 VACCINES WITH TOCOPHEROL-CONTAINING SQUALENE EMULSION ADJUVANTS
    Publication number: 20240269270
    Abstract: Provided are novel vaccines for prophylactic treatment of SARS-COV-2 infections and COVID-19 and methods of making the vaccines, wherein the vaccines contain an oil-in-water emulsion comprising tocopherol and squalene.
    Type: Application
    Filed: August 23, 2021
    Publication date: August 15, 2024
    Applicants: SANOFI PASTEUR INC., GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Natalie ANOSOVA, Salvador Fernando AUSAR, Catherine BERRY, Florence BOUDET, Thomas BREUER, Danilo CASIMIRO, Roman M. CHICZ, Gustavo DAYAN, Guy DE BRUYN, Carlos DIAZGRANADOS, Tong-Ming FU, Marie GARINOT, Lorry GRADY, Sanjay GURUNATHAN, Kirill KALNIN, Nikolai KHRAMTSOV, Valérie LECOUTURIER, Nausheen RAHMAN, Sophie RUIZ, Stephen SAVARINO, Saranya SRIDHAR, Indresh K. SRIVASTAVA, James TARTAGLIA, Timothy TIBBITTS
  • LIPID NANOPARTICLES FOR DELIVERING mRNA VACCINES
    Publication number: 20240148651
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Application
    Filed: August 30, 2023
    Publication date: May 9, 2024
    Inventors: Danilo CASIMIRO, Sudha CHIVUKULA, Kirill KALNIN, Timothy PLITNIK, Timothy TIBBITTS, Angela Lynne BEAULIEU, Frank DEROSA, Anusha DIAS, Rebecca L. GOLDMAN, Hardip Rajeshbhai GOPANI, Shrirang KARVE, Asad KHANMOHAMMED, Natalia VARGAS MONTOYA, Priyal PATEL, Ashish L. SARODE, Khang Anh TRAN
  • LIPID NANOPARTICLES FOR DELIVERING mRNA VACCINES
    Publication number: 20240091154
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Application
    Filed: November 7, 2023
    Publication date: March 21, 2024
    Inventors: Danilo CASIMIRO, Sudha CHIVUKULA, Kirill KALNIN, Timothy PLITNIK, Timothy TIBBITTS, Angela Lynne BEAULIEU, Frank DEROSA, Anusha DIAS, Rebecca L. GOLDMAN, Hardip Rajeshbhai GOPANI, Shrirang KARVE, Asad KHANMOHAMMED, Natalia VARGAS MONTOYA, Priyal PATEL, Ashish L. SARODE, Khang Anh TRAN
  • VACCINES AGAINST SARS-COV-2 INFECTIONS
    Publication number: 20240016918
    Abstract: Provided are novel vaccines for prophylactic treatment of SARS-CoV-2 infections and COVID-19 and methods of making the vaccines.
    Type: Application
    Filed: August 23, 2021
    Publication date: January 18, 2024
    Applicant: SANOFI PASTEUR INC.
    Inventors: Natalie ANOSOVA, Salvador Fernando AUSAR, Catherine BERRY, Florence BOUDET, Danilo CASIMIRO, Roman M. CHICZ, Gustavo DAYAN, Guy DE BRUYN, Carlos DIAZGRANADOS, Tong-Ming FU, Marie GARINOT, Lorry GRADY, Sanjay GURUNATHAN, Kirill KALNIN, Nikolai KHRAMTSOV, Valérie LECOUTURIER, Nausheen RAHMAN, Sophie RUIZ, Stephen SAVARINO, Saranya SRIDHAR, Indresh K. SRIVASTAVA, James TARTAGLIA, Timothy TIBBITTS
  • Lipid nanoparticles for delivering mRNA vaccines
    Patent number: 11771653
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Grant
    Filed: June 30, 2022
    Date of Patent: October 3, 2023
    Assignee: SANOFI
    Inventors: Danilo Casimiro, Sudha Chivukula, Kirill Kalnin, Timothy Plitnik, Timothy Tibbitts, Frank Derosa, Anusha Dias, Rebecca L. Goldman, Hardip Rajeshbhai Gopani, Shrirang Karve, Asad Khanmohammed, Priyal Patel
  • Lipid nanoparticles for delivering mRNA vaccines
    Patent number: 11771652
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: October 3, 2023
    Assignee: SANOFI
    Inventors: Danilo Casimiro, Sudha Chivukula, Kirill Kalnin, Timothy Plitnik, Timothy Tibbitts, Frank Derosa, Anusha Dias, Rebecca L. Goldman, Hardip Rajeshbhai Gopani, Shrirang Karve, Asad Khanmohammed, Priyal Patel
  • RESPIRATORY SYNCTIAL VIRUS RNA VACCINE
    Publication number: 20230302112
    Abstract: The present disclosure provides a respiratory syncytial virus (RSV) vaccine comprising a messenger RNA (mRNA) comprising an open reading frame (ORF) encoding an RSV F protein antigen, and methods of eliciting an immune response by administering said vaccine.
    Type: Application
    Filed: November 4, 2022
    Publication date: September 28, 2023
    Inventors: Danilo Casimiro, Hardip Rajeshbhai Gopani, Joshua DiNapoli, Linong Zhang, Mark Parrington, Rebecca L. Goldman, Sudha Chivukula, William Scott Gallichan
  • Tuberculosis Antigen Cassettes
    Publication number: 20230270834
    Abstract: The present disclosure provides fusion proteins comprising Mycobacterium tuberculosis (Mtb) antigens, nucleic acid molecules encoding the same, vectors comprising nucleic acid molecules, compositions comprising the same, and methods of eliciting an immune response against tuberculosis.
    Type: Application
    Filed: March 16, 2023
    Publication date: August 31, 2023
    Inventors: Dominick Laddy, Danilo Casimiro, Thomas Evans, Megan Fitzpatrick Forrest, Nathalie Cadieux
  • Tuberculosis antigen cassettes
    Patent number: 11638749
    Abstract: The present disclosure provides fusion proteins comprising Mycobacterium tuberculosis (Mtb) antigens, nucleic acid molecules encoding the same, vectors comprising nucleic acid molecules, compositions comprising the same, and methods of eliciting an immune response against tuberculosis.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: May 2, 2023
    Assignee: International AIDS Vaccine Initiative, Inc.
    Inventors: Dominick Laddy, Danilo Casimiro, Thomas Evans, Megan Fitzpatrick Forrest, Nathalie Cadieux
  • LIPID NANOPARTICLES FOR DELIVERING mRNA VACCINES
    Publication number: 20220378701
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Application
    Filed: June 30, 2022
    Publication date: December 1, 2022
    Inventors: Danilo CASIMIRO, Sudha CHIVUKULA, Kirill KALNIN, Timothy PLITNIK, Timothy TIBBITTS, Angela Lynne BEAULIEU, Frank DEROSA, Anusha DIAS, Rebecca L. GOLDMAN, Hardip Rajeshbhai GOPANI, Shrirang KARVE, Asad KHANMOHAMMED, Natalia VARGAS MONTOYA, Priyal PATEL, Ashish L. SARODE, Khang Anh TRAN
  • LIPID NANOPARTICLES FOR DELIVERING mRNA VACCINES
    Publication number: 20220347100
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Application
    Filed: June 30, 2022
    Publication date: November 3, 2022
    Inventors: Danilo CASIMIRO, Sudha CHIVUKULA, Kirill KALNIN, Timothy PLITNIK, Timothy TIBBITTS, Angela Lynne BEAULIEU, Frank DEROSA, Anusha DIAS, Rebecca L. GOLDMAN, Hardip Rajeshbhai GOPANI, Shrirang KARVE, Asad KHANMOHAMMED, Natalia VARGAS MONTOYA, Priyal PATEL, Ashish L. SARODE, Khang Anh TRAN
  • LIPID NANOPARTICLES FOR DELIVERING mRNA VACCINES
    Publication number: 20220142923
    Abstract: Provided are novel lipid nanoparticles for delivering nucleic acids such as mRNA. Also provided are methods of making and using lipid nanoparticles for delivering nucleic acids such as mRNA.
    Type: Application
    Filed: November 5, 2021
    Publication date: May 12, 2022
    Inventors: Danilo CASIMIRO, Sudha CHIVUKULA, Kirill KALNIN, Timothy PLITNIK, Timothy TIBBITTS, Angela Lynne BEAULIEU, Frank DEROSA, Anusha DIAS, Rebecca L. GOLDMAN, Hardip Rajeshbhai GOPANI, Shrirang KARVE, Asad KHANMOHAMMED, Natalia VARGAS MONTOYA, Priyal PATEL, Ashish L. SARODE, Khang Anh TRAN
  • TUBERCULOSIS ANTIGEN CASSETTES
    Publication number: 20200282038
    Abstract: The present disclosure provides fusion proteins comprising Mycobacterium tuberculosis (Mtb) antigens, nucleic acid molecules encoding the same, vectors comprising nucleic acid molecules, compositions comprising the same, and methods of eliciting an immune response against tuberculosis.
    Type: Application
    Filed: October 15, 2018
    Publication date: September 10, 2020
    Inventors: Dominick Laddy, Danilo Casimiro, Thomas Evans, Megan Fitzpatrick, Nathalie Cadieux