Patents by Inventor Danli Wu

Danli Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11999769
    Abstract: The present disclosure discloses a method for isolating and purifying Lactobacillus rhamnosus ZFM216 bacteriocin, the method including the following steps: preparing L. rhamnosus ZFM216 fermentation supernatant; treating the fermentation supernatant with macroporous adsorption resin method to obtain a crude protein extract; isolating the crude protein extract by gel chromatography to obtain a preliminary purified protein solution; and then performing purification by reversed-phase high performance liquid chromatography (HPLC) to obtain an L. rhamnosus ZFM216 bacteriocin solution. The present disclosure further provides use of the L. rhamnosus bacteriocin in anti-Staphylococcus aureus.
    Type: Grant
    Filed: November 11, 2022
    Date of Patent: June 4, 2024
    Assignee: Zhejiang Gongshang University
    Inventors: Qing Gu, Mengdi Dai, Qingqing Zhou, Ping Li, Danli Wu
  • Publication number: 20230348544
    Abstract: The present disclosure discloses a method for isolating and purifying Lactobacillus rhamnosus ZFM216 bacteriocin, the method including the following steps: preparing L. rhamnosus ZFM216 fermentation supernatant; treating the fermentation supernatant with macroporous adsorption resin method to obtain a crude protein extract; isolating the crude protein extract by gel chromatography to obtain a preliminary purified protein solution; and then performing purification by reversed-phase high performance liquid chromatography (HPLC) to obtain an L. rhamnosus ZFM216 bacteriocin solution. The present disclosure further provides use of the L. rhamnosus bacteriocin in anti-Staphylococcus aureus.
    Type: Application
    Filed: November 11, 2022
    Publication date: November 2, 2023
    Inventors: Qing Gu, Mengdi Dai, Qingqing Zhou, Ping Li, Danli Wu
  • Publication number: 20220389663
    Abstract: A guide rail beam (10), a track beam unit (100), and a track beam (1000) for a rail vehicle (7) are disclosed. The guide rail beam (10) includes a fixing plate (1), a flange plate (2), a web plate (3), and a stiffening rib (5). The fixing plate (1) is disposed on a mounting surface (20). The flange plate (2) is disposed above the fixing plate (1). A road wheel (71) travels on the flange plate (2). An upper end of the web plate (3) is connected with the flange plate (2), and a lower end of the web plate (3) is connected with the fixing plate (1). The web plate (3) is in contact with and be associated with a guide wheel (72) to guide a traveling track of the guide wheel (72). An upper end of the stiffening rib (5) is connected with the flange plate (2), and a lower end of the stiffening rib (5) is connected with the fixing plate (1).
    Type: Application
    Filed: September 23, 2020
    Publication date: December 8, 2022
    Inventors: Saining WANG, Xiaotong LIU, Jing YANG, Dandan GUAN, Danli WU
  • Patent number: 8361795
    Abstract: Provided are a hepatopoietin PCn (HPPCn) and its homologous proteins, which can promote hepatocyte proliferation in vitro, promote liver regeneration in vivo, inhibit the growth of tumor cells and promote the apoptosis of tumor cells. The hepatopoietin PCn (HPPCn) and its homologous proteins are useful for the treatment of acute and chronic liver injury, or the treatment of liver fibrosis.
    Type: Grant
    Filed: December 21, 2007
    Date of Patent: January 29, 2013
    Assignee: Institute of Radiation Medicine, Academy of Military Medical Sciences, PLA
    Inventors: Zuze Wu, Bingxing Shi, Chunping Cui, Shaojun Du, Danli Wu
  • Publication number: 20100144628
    Abstract: Provided are a hepatopoietin PCn (HPPCn) and its homologous proteins, which can promote hepatocyte proliferation in vitro, promote liver regeneration in vivo, inhibit the growth of tumor cells and promote the apoptosis of tumor cells. The hepatopoietin PCn (HPPCn) and its homologous proteins are useful for the treatment of acute and chronic liver injury, or the treatment of liver fibrosis.
    Type: Application
    Filed: December 21, 2007
    Publication date: June 10, 2010
    Applicant: INSTITUTE OF RADIATION MEDICINE, ACADEMY OF MILITA
    Inventors: Zuze Wu, Bingxing Shi, Chunping Cui, Shaojun Du, Danli Wu