Abstract: The present invention relates to a pharmaceutical composition comprising PD-1 antagonist and an EGFR Inhibitor. The present combination can be administered independently or separately, in a quantity which is jointly therapeutically effective for the treatment of cancer. The invention also provides the use of such a combination for the manufacture of a medicament; the use of such a combination as a medicine; a kit of part comprising such a combination; and a method of treatment of such a combination.

Abstract: A system and method to enhance attitude estimation for transfer orbit maneuvers of a spinning satellite includes a transfer orbit earth sensor that can receive and convert an infrared radiance to an analog signal. The analog signal is provided to a hardware chord processor and an analog-to-digital converter. The hardware chord processor determines an earth chord length based on the analog signal. The analog signal is sampled in the analog-to-digital converter to provide a digital signal to a digital earth sensor pre-processor, which reshapes the digital signal to provide a pre-processed signal having nearly distinct peaks. A software chord processor is provided with the pre-processed signal. The software chord processor locates the peaks in the pre-processed signal and determines an earth chord length.