Patents by Inventor Danny Jonigk

Danny Jonigk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMARKER PANEL FOR DIAGNOSING PULMONARY DYSFUNCTION
    Publication number: 20260177558
    Abstract: The present invention pertains to a new method for the diagnosis, prognosis, stratification and/or monitoring of a therapy, of a pulmonary dysfunction in a subject. The method is based on the determination of the level of a panel of biomarkers selected from TM4SF18, TRGV9, ADORA2A, H963, IRF2, TNFSF14, TRIB1, SMAD3, TSLP, SLAMF8, THBS1, SOD1, HAS2, TLR2, THBD, TRA, TFEC, SPHK1, COL3A1, Elastin, IL6R, SN, TEK, SOX7, CXCL9, CXCL10, SLC38A6, SLC15A3, TGFA, SLPI, VWF, TLR8, TGFB1, CXCR6, CCL24, PD1, PLA1A, TRD, CTLA4, MMP9, CD301, PDL1, PDL2, TGFB1, CXCR6, CCL24, PD1, PLA1A, TRD, CTLA4, MMP9, and CD301. The new biomarker panels of this invention allow diagnosing and even stratifying various pulmonary dysfunctions in a subject, and even allow early detection of Chronic lung allograft dysfunction (CLAD). Furthermore provided are diagnostic kits for performing the methods of the invention.
    Type: Application
    Filed: November 7, 2022
    Publication date: June 25, 2026
    Inventors: Danny JONIGK, Florian LÄNGER, Helge STARK, Mark KÜHNEL
  • Embedding medium for biological samples, method for producing embedded biological samples, and use thereof
    Patent number: 10401266
    Abstract: In a first aspect, the invention relates to the use of a UV-polymerizable composition as an embedding medium for biological samples. The UV-polymerizable composition is a composition with a refractive index ranging from n=1.45 to n=1.6 after a polymerization process. In another aspect, the invention relates to a method for producing embedded biological samples using said UV-polymerizable composition and to the embedded biological samples themselves. The biological samples can be used in a wide variety of areas, such as diagnostics among others, and are suitable in particular for RNA-based diagnostics.
    Type: Grant
    Filed: June 19, 2015
    Date of Patent: September 3, 2019
    Assignee: Laser Zentrum Hannover e.V.
    Inventors: Mark Kuehnel, Manuela Kellner, Danny Jonigk, Nicole Izykowski, Heiko Meyer, Raoul-Amadeus Lorbeer, Marko Heidrich
  • Embedding Medium for Biological Samples, Method for Producing Embedded Biological Samples, and Use Thereof
    Publication number: 20170212020
    Abstract: In a first aspect, the invention relates to the use of a UV-polymerizable composition as an embedding medium for biological samples. The UV-polymerizable composition is a composition with a refractive index ranging from n=1.45 to n=1.6 after a polymerization process. In another aspect, the invention relates to a method for producing embedded biological samples using said UV-polymerizable composition and to the embedded biological samples themselves. The biological samples can be used in a wide variety of areas, such as diagnostics among others, and are suitable in particular for RNA-based diagnostics.
    Type: Application
    Filed: June 19, 2015
    Publication date: July 27, 2017
    Inventors: Mark Kuehnel, Manuela Kellner, Danny Jonigk, Nicole Izykowski, Heiko Meyer, Raoul-Amadeus Lorbeer, Marko Heidrich