Patents by Inventor Danny Macari
Danny Macari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250388872Abstract: A method for transporting a biological sample at hypothermic temperatures. The container can be cooled using phase change material and pump fluid through the sample. The fluid can pump through the system at a rate independent of the parameters of the biological sample. A valve can control the rate of flow of the fluid into the biological sample.Type: ApplicationFiled: September 8, 2025Publication date: December 25, 2025Inventors: Danny Macari, Matthew Whitney, Samantha Estrella, William Lucas Churchill
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Patent number: 12410408Abstract: A method for transporting a biological sample at hypothermic temperatures. The container can be cooled using phase change material and pump fluid through the sample. The fluid can pump through the system at a rate independent of the parameters of the biological sample. A valve can control the rate of flow of the fluid into the biological sample.Type: GrantFiled: January 30, 2025Date of Patent: September 9, 2025Assignee: Paragonix Technologies, Inc.Inventors: Danny Macari, Matthew Whitney, Samantha Estrella, William Lucas Churchill
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Publication number: 20250248390Abstract: A system for perfusing an organ, for example a kidney or a heart. Preservation fluid can be pumped from a transport container to the organ through a cannula or organ adapter. A flow regulator valve can control the rate of flow of the preservation fluid based on renal resistance of the kidney or arterial resistance of the organ. The pump can operate at a rate independent of the arterial resistance.Type: ApplicationFiled: January 30, 2025Publication date: August 7, 2025Inventors: Danny Macari, Matthew Whitney, Samantha Estrella, William Lucas Churchill
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Publication number: 20250250546Abstract: A method for transporting a biological sample at hypothermic temperatures. The container can be cooled using phase change material and pump fluid through the sample. The fluid can pump through the system at a rate independent of the parameters of the biological sample. A valve can control the rate of flow of the fluid into the biological sample.Type: ApplicationFiled: January 30, 2025Publication date: August 7, 2025Inventors: Danny Macari, Matthew Whitney, Samantha Estrella, William Lucas Churchill
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Publication number: 20240369056Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.Type: ApplicationFiled: July 16, 2024Publication date: November 7, 2024Applicant: HOLOGIC, INC.Inventors: Danny Macari, Mathew John Whitney
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Publication number: 20240350717Abstract: A method for operating a fluid management system includes automatically detecting an unstable condition in the system, which may include detecting a large change in the supply fluid amount (indicative of a bag change), detecting a large change in the waste fluid amount (indicative of a bag change), or detecting a large difference between the amount of fluid dispensed as measured by the weight data and the amount of fluid dispensed as measured by the flow data (indicative of a blockage in the supply tubing). The method further includes adjusting the operating mode of the system during the unstable condition, which may include switching to using flow data rather than weight data to track the fluid deficit during a supply bag exchange, halting operation of an outflow pump during a waste container exchange, and/or halting operation of the system during a blockage in the supply tubing.Type: ApplicationFiled: June 28, 2024Publication date: October 24, 2024Applicant: HOLOGIC, INC.Inventors: David J. Holigan, Joanna Myczkowska, William Lucas Churchill, Danny Macari
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Patent number: 12048799Abstract: A method for operating a fluid management system includes automatically detecting an unstable condition in the system, which may include detecting a large change in the supply fluid amount (indicative of a bag change), detecting a large change in the waste fluid amount (indicative of a bag change), or detecting a large difference between the amount of fluid dispensed as measured by the weight data and the amount of fluid dispensed as measured by the flow data (indicative of a blockage in the supply tubing). The method further includes adjusting the operating mode of the system during the unstable condition, which may include switching to using flow data rather than weight data to track the fluid deficit during a supply bag exchange, halting operation of an outflow pump during a waste container exchange, and/or halting operation of the system during a blockage in the supply tubing.Type: GrantFiled: April 14, 2022Date of Patent: July 30, 2024Assignee: Hologic, Inc.Inventors: David J. Holigan, Joanna Myczkowska, William Lucas Churchill, Danny Macari
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Patent number: 12049886Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.Type: GrantFiled: December 2, 2022Date of Patent: July 30, 2024Assignee: Hologic, Inc.Inventors: Danny Macari, Mathew John Whitney
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Publication number: 20230096757Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.Type: ApplicationFiled: December 2, 2022Publication date: March 30, 2023Applicant: HOLOGIC, INC.Inventors: Danny Macari, Mathew John Whitney
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Patent number: 11525440Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.Type: GrantFiled: May 11, 2021Date of Patent: December 13, 2022Assignee: Hologic, MAInventors: Danny Macari, Mathew John Whitney
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Publication number: 20220233758Abstract: A method for operating a fluid management system includes automatically detecting an unstable condition in the system, which may include detecting a large change in the supply fluid amount (indicative of a bag change), detecting a large change in the waste fluid amount (indicative of a bag change), or detecting a large difference between the amount of fluid dispensed as measured by the weight data and the amount of fluid dispensed as measured by the flow data (indicative of a blockage in the supply tubing). The method further includes adjusting the operating mode of the system during the unstable condition, which may include switching to using flow data rather than weight data to track the fluid deficit during a supply bag exchange, halting operation of an outflow pump during a waste container exchange, and/or halting operation of the system during a blockage in the supply tubing.Type: ApplicationFiled: April 14, 2022Publication date: July 28, 2022Applicant: HOLOGIC, INC.Inventors: David J. Holigan, Joanna Myczkowska, William Lucas Churchill, Danny Macari
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Patent number: 11311660Abstract: A method for operating a fluid management system includes automatically detecting an unstable condition in the system, which may include detecting a large change in the supply fluid amount (indicative of a bag change), detecting a large change in the waste fluid amount (indicative of a bag change), or detecting a large difference between the amount of fluid dispensed as measured by the weight data and the amount of fluid dispensed as measured by the flow data (indicative of a blockage in the supply tubing). The method further includes adjusting the operating mode of the system during the unstable condition, which may include switching to using flow data rather than weight data to track the fluid deficit during a supply bag exchange, halting operation of an outflow pump during a waste container exchange, and/or halting operation of the system during a blockage in the supply tubing.Type: GrantFiled: July 31, 2019Date of Patent: April 26, 2022Assignee: Hologic, Inc.Inventors: David J. Holigan, Joanna Myczkowska, William Lucas Churchill, Danny Macari
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Publication number: 20210262462Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.Type: ApplicationFiled: May 11, 2021Publication date: August 26, 2021Applicant: HOLOGIC, INC.Inventors: Danny Macari, Mathew John Whitney
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Patent number: 11009021Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.Type: GrantFiled: September 17, 2018Date of Patent: May 18, 2021Assignee: Hologic, Inc.Inventors: Danny Macari, Mathew John Whitney
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Publication number: 20200297900Abstract: A method for operating a fluid management system includes automatically detecting an unstable condition in the system, which may include detecting a large change in the supply fluid amount (indicative of a bag change), detecting a large change in the waste fluid amount (indicative of a bag change), or detecting a large difference between the amount of fluid dispensed as measured by the weight data and the amount of fluid dispensed as measured by the flow data (indicative of a blockage in the supply tubing). The method further includes adjusting the operating mode of the system during the unstable condition, which may include switching to using flow data rather than weight data to track the fluid deficit during a supply bag exchange, halting operation of an outflow pump during a waste container exchange, and/or halting operation of the system during a blockage in the supply tubing.Type: ApplicationFiled: July 31, 2019Publication date: September 24, 2020Applicant: HOLOGIC, INC.Inventors: David J. HOLIGAN, Joanna MYCZKOWSKA, William Lucas CHURCHILL, Danny MACARI
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Publication number: 20190120223Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.Type: ApplicationFiled: September 17, 2018Publication date: April 25, 2019Applicant: HOLOGIC, INC.Inventors: Danny MACARI, Mathew John Whitney
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Patent number: 10077767Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.Type: GrantFiled: December 22, 2016Date of Patent: September 18, 2018Assignee: HOLOGIC, INC.Inventors: Danny Macari, Mathew John Whitney
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Publication number: 20170184088Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.Type: ApplicationFiled: December 22, 2016Publication date: June 29, 2017Inventors: Danny Macari, Mathew John Whitney
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Publication number: 20100094089Abstract: A proximal connector of an endoscope shaft can be manually attached to and detached from a console, such that the connector and endoscope shaft can be provided as a single use device. An interface between the proximal connector and console can include a sliding plate moveable to operably make and break at least some of the connections between the console and endoscope shaft. A fluid reservoir may be separately connected to the proximal connector and hang from a mount on the interface.Type: ApplicationFiled: September 30, 2009Publication date: April 15, 2010Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Eric Litscher, Gerald Heller, Danny Macari, Charles McCall, Eric Rioux, Gary Searle, Arthur Stephen
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Patent number: D1087382Type: GrantFiled: January 30, 2025Date of Patent: August 5, 2025Assignee: Paragonix Technologies, Inc.Inventors: Danny Macari, Matthew Whitney, Samantha Estrella, William Lucas Churchill, Daniel Rapoport