Patents by Inventor Danny Macari

Danny Macari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250388872
    Abstract: A method for transporting a biological sample at hypothermic temperatures. The container can be cooled using phase change material and pump fluid through the sample. The fluid can pump through the system at a rate independent of the parameters of the biological sample. A valve can control the rate of flow of the fluid into the biological sample.
    Type: Application
    Filed: September 8, 2025
    Publication date: December 25, 2025
    Inventors: Danny Macari, Matthew Whitney, Samantha Estrella, William Lucas Churchill
  • Patent number: 12410408
    Abstract: A method for transporting a biological sample at hypothermic temperatures. The container can be cooled using phase change material and pump fluid through the sample. The fluid can pump through the system at a rate independent of the parameters of the biological sample. A valve can control the rate of flow of the fluid into the biological sample.
    Type: Grant
    Filed: January 30, 2025
    Date of Patent: September 9, 2025
    Assignee: Paragonix Technologies, Inc.
    Inventors: Danny Macari, Matthew Whitney, Samantha Estrella, William Lucas Churchill
  • Publication number: 20250248390
    Abstract: A system for perfusing an organ, for example a kidney or a heart. Preservation fluid can be pumped from a transport container to the organ through a cannula or organ adapter. A flow regulator valve can control the rate of flow of the preservation fluid based on renal resistance of the kidney or arterial resistance of the organ. The pump can operate at a rate independent of the arterial resistance.
    Type: Application
    Filed: January 30, 2025
    Publication date: August 7, 2025
    Inventors: Danny Macari, Matthew Whitney, Samantha Estrella, William Lucas Churchill
  • Publication number: 20250250546
    Abstract: A method for transporting a biological sample at hypothermic temperatures. The container can be cooled using phase change material and pump fluid through the sample. The fluid can pump through the system at a rate independent of the parameters of the biological sample. A valve can control the rate of flow of the fluid into the biological sample.
    Type: Application
    Filed: January 30, 2025
    Publication date: August 7, 2025
    Inventors: Danny Macari, Matthew Whitney, Samantha Estrella, William Lucas Churchill
  • Publication number: 20240369056
    Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.
    Type: Application
    Filed: July 16, 2024
    Publication date: November 7, 2024
    Applicant: HOLOGIC, INC.
    Inventors: Danny Macari, Mathew John Whitney
  • Publication number: 20240350717
    Abstract: A method for operating a fluid management system includes automatically detecting an unstable condition in the system, which may include detecting a large change in the supply fluid amount (indicative of a bag change), detecting a large change in the waste fluid amount (indicative of a bag change), or detecting a large difference between the amount of fluid dispensed as measured by the weight data and the amount of fluid dispensed as measured by the flow data (indicative of a blockage in the supply tubing). The method further includes adjusting the operating mode of the system during the unstable condition, which may include switching to using flow data rather than weight data to track the fluid deficit during a supply bag exchange, halting operation of an outflow pump during a waste container exchange, and/or halting operation of the system during a blockage in the supply tubing.
    Type: Application
    Filed: June 28, 2024
    Publication date: October 24, 2024
    Applicant: HOLOGIC, INC.
    Inventors: David J. Holigan, Joanna Myczkowska, William Lucas Churchill, Danny Macari
  • Patent number: 12048799
    Abstract: A method for operating a fluid management system includes automatically detecting an unstable condition in the system, which may include detecting a large change in the supply fluid amount (indicative of a bag change), detecting a large change in the waste fluid amount (indicative of a bag change), or detecting a large difference between the amount of fluid dispensed as measured by the weight data and the amount of fluid dispensed as measured by the flow data (indicative of a blockage in the supply tubing). The method further includes adjusting the operating mode of the system during the unstable condition, which may include switching to using flow data rather than weight data to track the fluid deficit during a supply bag exchange, halting operation of an outflow pump during a waste container exchange, and/or halting operation of the system during a blockage in the supply tubing.
    Type: Grant
    Filed: April 14, 2022
    Date of Patent: July 30, 2024
    Assignee: Hologic, Inc.
    Inventors: David J. Holigan, Joanna Myczkowska, William Lucas Churchill, Danny Macari
  • Patent number: 12049886
    Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.
    Type: Grant
    Filed: December 2, 2022
    Date of Patent: July 30, 2024
    Assignee: Hologic, Inc.
    Inventors: Danny Macari, Mathew John Whitney
  • Publication number: 20230096757
    Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.
    Type: Application
    Filed: December 2, 2022
    Publication date: March 30, 2023
    Applicant: HOLOGIC, INC.
    Inventors: Danny Macari, Mathew John Whitney
  • Patent number: 11525440
    Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.
    Type: Grant
    Filed: May 11, 2021
    Date of Patent: December 13, 2022
    Assignee: Hologic, MA
    Inventors: Danny Macari, Mathew John Whitney
  • Publication number: 20220233758
    Abstract: A method for operating a fluid management system includes automatically detecting an unstable condition in the system, which may include detecting a large change in the supply fluid amount (indicative of a bag change), detecting a large change in the waste fluid amount (indicative of a bag change), or detecting a large difference between the amount of fluid dispensed as measured by the weight data and the amount of fluid dispensed as measured by the flow data (indicative of a blockage in the supply tubing). The method further includes adjusting the operating mode of the system during the unstable condition, which may include switching to using flow data rather than weight data to track the fluid deficit during a supply bag exchange, halting operation of an outflow pump during a waste container exchange, and/or halting operation of the system during a blockage in the supply tubing.
    Type: Application
    Filed: April 14, 2022
    Publication date: July 28, 2022
    Applicant: HOLOGIC, INC.
    Inventors: David J. Holigan, Joanna Myczkowska, William Lucas Churchill, Danny Macari
  • Patent number: 11311660
    Abstract: A method for operating a fluid management system includes automatically detecting an unstable condition in the system, which may include detecting a large change in the supply fluid amount (indicative of a bag change), detecting a large change in the waste fluid amount (indicative of a bag change), or detecting a large difference between the amount of fluid dispensed as measured by the weight data and the amount of fluid dispensed as measured by the flow data (indicative of a blockage in the supply tubing). The method further includes adjusting the operating mode of the system during the unstable condition, which may include switching to using flow data rather than weight data to track the fluid deficit during a supply bag exchange, halting operation of an outflow pump during a waste container exchange, and/or halting operation of the system during a blockage in the supply tubing.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: April 26, 2022
    Assignee: Hologic, Inc.
    Inventors: David J. Holigan, Joanna Myczkowska, William Lucas Churchill, Danny Macari
  • Publication number: 20210262462
    Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.
    Type: Application
    Filed: May 11, 2021
    Publication date: August 26, 2021
    Applicant: HOLOGIC, INC.
    Inventors: Danny Macari, Mathew John Whitney
  • Patent number: 11009021
    Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.
    Type: Grant
    Filed: September 17, 2018
    Date of Patent: May 18, 2021
    Assignee: Hologic, Inc.
    Inventors: Danny Macari, Mathew John Whitney
  • Publication number: 20200297900
    Abstract: A method for operating a fluid management system includes automatically detecting an unstable condition in the system, which may include detecting a large change in the supply fluid amount (indicative of a bag change), detecting a large change in the waste fluid amount (indicative of a bag change), or detecting a large difference between the amount of fluid dispensed as measured by the weight data and the amount of fluid dispensed as measured by the flow data (indicative of a blockage in the supply tubing). The method further includes adjusting the operating mode of the system during the unstable condition, which may include switching to using flow data rather than weight data to track the fluid deficit during a supply bag exchange, halting operation of an outflow pump during a waste container exchange, and/or halting operation of the system during a blockage in the supply tubing.
    Type: Application
    Filed: July 31, 2019
    Publication date: September 24, 2020
    Applicant: HOLOGIC, INC.
    Inventors: David J. HOLIGAN, Joanna MYCZKOWSKA, William Lucas CHURCHILL, Danny MACARI
  • Publication number: 20190120223
    Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.
    Type: Application
    Filed: September 17, 2018
    Publication date: April 25, 2019
    Applicant: HOLOGIC, INC.
    Inventors: Danny MACARI, Mathew John Whitney
  • Patent number: 10077767
    Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: September 18, 2018
    Assignee: HOLOGIC, INC.
    Inventors: Danny Macari, Mathew John Whitney
  • Publication number: 20170184088
    Abstract: A pump cartridge for mounting on a drive rotor includes a roller assembly having first and second hubs maintained in a spaced apart relationship and defining an axis, and a plurality of planetary rollers arranged in a circumferentially spaced orientation about the axis, the rollers mounted to the hubs displacement radially outward. One or more compressible tubing lines are interposed between the rollers and an interior wall of the pump cartridge housing. The housing and the first and second hubs collectively define a passageway through which a spreader on the drive rotor extends and may be rotated relative to the roller assembly to displace the rollers radially outward to thereby compress the tubing lines against the interior wall. A coupling feature on the first hub engages a roller driving feature of the rotor, so that rotation of the rotor causes rotation of the roller assembly about the axis.
    Type: Application
    Filed: December 22, 2016
    Publication date: June 29, 2017
    Inventors: Danny Macari, Mathew John Whitney
  • Publication number: 20100094089
    Abstract: A proximal connector of an endoscope shaft can be manually attached to and detached from a console, such that the connector and endoscope shaft can be provided as a single use device. An interface between the proximal connector and console can include a sliding plate moveable to operably make and break at least some of the connections between the console and endoscope shaft. A fluid reservoir may be separately connected to the proximal connector and hang from a mount on the interface.
    Type: Application
    Filed: September 30, 2009
    Publication date: April 15, 2010
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Eric Litscher, Gerald Heller, Danny Macari, Charles McCall, Eric Rioux, Gary Searle, Arthur Stephen
  • Patent number: D1087382
    Type: Grant
    Filed: January 30, 2025
    Date of Patent: August 5, 2025
    Assignee: Paragonix Technologies, Inc.
    Inventors: Danny Macari, Matthew Whitney, Samantha Estrella, William Lucas Churchill, Daniel Rapoport