Patents by Inventor Danny Mancheno

Danny Mancheno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing N-alkylated hydroxypyrimidinone compounds
    Patent number: 8357798
    Abstract: Potassium salts of Compound A and methods for their preparation are disclosed, wherein Compound A is of formula: Compound A is an HIV integrase inhibitor useful for treating or prophylaxis of HIV infection, for delaying the onset of AIDS, and for treating or prophylaxis of AIDS.
    Type: Grant
    Filed: June 4, 2010
    Date of Patent: January 22, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Kevin M. Belyk, Henry G. Morrison, Philip Jones, Vincenzo Summa, V. Brett Cooper, Amar J. Mahajan, Daniel J. Kumke, Hsien-Hsin Tung, Lawrence Wai, Vanessa Pruzinsky, Philip Pye, Remy Angelaud, Danny Mancheno
  • PROCESS FOR PREPARING N-ALKYLATED HYDROXYPYRIMIDINONE COMPOUNDS
    Publication number: 20100249410
    Abstract: Potassium salts of Compound A and methods for their preparation are disclosed, wherein Compound A is of formula: Compound A is an HIV integrase inhibitor useful for treating or prophylaxis of HIV infection, for delaying the onset of AIDS, and for treating or prophylaxis of AIDS.
    Type: Application
    Filed: June 4, 2010
    Publication date: September 30, 2010
    Inventors: Philip Pye, Remy Angelaud, Danny Mancheno
  • Hiv integrase inhibitors
    Publication number: 20070179196
    Abstract: Hydroxy (tetra- or hexa-)hydronaphthyridine dione compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication: (I) wherein a, R,1?, R,2?, R,3?, R,4? and R,5? are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention, delay in the onset, and treatment of AIDS. The compounds are employed against HIV infection and AIDS as compounds per se or in the form of pharmaceutically acceptable salts. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
    Type: Application
    Filed: March 9, 2005
    Publication date: August 2, 2007
    Inventors: Wei Han, Melissa Egbertson, John Wai, Linghang Zhuang, Rowena Ruzek, Debra Perlow, Richard Isaacs, Mark Cameron, Bruce Foster, Ulf Dolling, R. Hoermer, Vanessa Obligado, Lou Neilson, Boyoung Kim, Linda Payne, Matthew Morrissette, Peter Williams, Philip Pye, Remy Angelaud, Danny Mancheno, David Askin
  • Potassium salt of an HIV integrase inhibitor
    Publication number: 20060122205
    Abstract: Potassium salts of Compound A and methods for their preparation are disclosed, wherein Compound A is of formula: Compound A is an HIV integrase inhibitor useful for treating or prophylaxis of HIV infection, for delaying the onset of AIDS, and for treating or prophylaxis of AIDS.
    Type: Application
    Filed: December 2, 2005
    Publication date: June 8, 2006
    Inventors: Kevin Belyk, Henry Morrison, Philip Jones, Vincenzo Summa, V. Cooper, Amar Mahajan, Daniel Kumke, Hsien-Hsin Tung, Lawrence Wai, Vanessa Pruzinsky, Philip Pye, Remy Angelaud, Danny Mancheno