Abstract: A method of analysing a motional activity of particles with a motion detector including the steps of bringing at least one particle into contact with a flexible support, detecting at least one time-dependent signal that is indicative of deflections of the flexible support due to motions of the at least one particle, and evaluating the detected time-dependent signal. The evaluation includes analysing a time-dependency of the signal to derive a plurality of signal parameters from the signal that characterise a variation of the signal as a function of time, and executing a linking algorithm that has, as input variables, an input vector having at least a selection of the signal parameters, and has, as an output variable, at least one activity indicator that is indicative of a motional activity of the particle.