Patents by Inventor Danyi WU

Danyi WU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aromatic heterocyclic compound with kinase inhibitory activity
    Patent number: 12234232
    Abstract: Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.
    Type: Grant
    Filed: September 23, 2019
    Date of Patent: February 25, 2025
    Assignee: SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD.
    Inventors: Lei Jiang, Jianwen Deng, Zhiyong Feng, Shengyang Liu, Xudong Mao, Ke Shang, Jianyong Shou, Danyi Wu, Xiaoping Xie, Yuan Xu, Haixia Zhao, Jianhua Zhang, Mingwei Zheng
  • Compound having PD-L1 inhibitory activity, preparation method therefor and use thereof
    Patent number: 11787766
    Abstract: Provided are a compound for the prevention and treatment of diseases associated with PD-L1, a preparation method therefor and use thereof. Specifically, provided are the compound of formula I, the stereoisomer and the racemate thereof, or pharmaceutically acceptable salts thereof, and also provided is an application thereof in the preparation of a drug for the prevention and treatment of diseases associated with PD-L1.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: October 17, 2023
    Assignee: SHANGHAI ENNOVABIO PHARMACEUTICALS CO., LTD.
    Inventors: Lei Jiang, Jianwen Deng, Xiaoli Lu, Ke Shang, Jianyong Shou, Bing Wang, Danyi Wu, Xueli Xu, Yuan Xu, Yi Zhang, Mingwei Zheng
  • FIVE-AND-SIX-MEMBERED HETEROCYCLIC COMPOUND AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITOR
    Publication number: 20220144827
    Abstract: A class of five-membered fused with six-membered heterocyclic compounds represented by formula I and a pharmaceutical composition, preparation, and an application thereof are disclosed. These compounds have TRK kinase inhibitory activity and can treat diseases related to TRK dysfunction.
    Type: Application
    Filed: November 13, 2019
    Publication date: May 12, 2022
    Inventors: Lei JIANG, Zhiyong FENG, Xian JIN, Zhi QIAO, Jianyong SHOU, Ke SHANG, Danyi WU, Lingling XU, Yuan XU, Shuyun ZHANG, Yi ZHANG, Yuxing ZHANG
  • SIX-MEMBERED AND SIX-MEMBERED HETEROCYCLIC COMPOUND AND USES THEREOF SERVING AS PROTEIN RECEPTOR KINASE INHIBITOR
    Publication number: 20220017512
    Abstract: Provided are a preparation and applications of a six-membered fused with six-membered heterocyclic compound, specifically, provided in the present invention is a compound as represented by formula I as follows, where the definitions of the groups are as described in the description. The compound has TRK kinase inhibiting activity and can serve as a pharmaceutical composition for treating TRK dysfunction-related diseases.
    Type: Application
    Filed: November 13, 2019
    Publication date: January 20, 2022
    Inventors: Lei JIANG, Zhiyong FENG, Xian JIN, Zhi QIAO, Jianyong SHOU, Ke SHANG, Danyi WU, Lingling XU, Yuan XU, Shuyun ZHANG, Yi ZHANG, Yuxing ZHANG
  • AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY
    Publication number: 20210371415
    Abstract: Provided are a JAK kinase inhibitor, preparation and use thereof. In particular, provided is a compound of Formula I, wherein each group is as described in the specification. The compound has an excellent JAK inhibitory activity, and therefore can be used to prepare pharmaceutical compositions for the treatment of cancer and other diseases related to JAK activity.
    Type: Application
    Filed: September 23, 2019
    Publication date: December 2, 2021
    Inventors: Lei JIANG, Jianwen DENG, Zhiyong FENG, Shengyang LIU, Xudong MAO, Ke SHANG, Jianyong SHOU, Danyi WU, Xiaoping XIE, Yuan XU, Haixia ZHAO, Jianhua ZHANG, Mingwei ZHENG
  • COMPOUND HAVING PD-L1 INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20200392083
    Abstract: Provided are a compound for the prevention and treatment of diseases associated with PD-L1, a preparation method therefor and use thereof. Specifically, provided are the compound of formula I, the stereoisomer and the racemate thereof, or pharmaceutically acceptable salts thereof, and also provided is an application thereof in the preparation of a drug for the prevention and treatment of diseases associated with PD-Ll.
    Type: Application
    Filed: August 17, 2018
    Publication date: December 17, 2020
    Inventors: Lei JIANG, Jianwen DENG, Xiaoli LU, Ke SHANG, Jianyong SHOU, Bing WANG, Danyi WU, Xueli XU, Yuan XU, Yi ZHANG, Mingwei ZHENG