Patents by Inventor Dao Min Zhou
Dao Min Zhou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10378119Abstract: An electrode surface coating and method for manufacturing the electrode surface coating comprising a conductive substrate; a surface coating of platinum having a rough configuration and an increase in the surface area of 5 times to 500 times of the corresponding surface area resulting from the basic geometric shape of the electrode. A method for electroplating an electrode surface with platinum coating having a rough surface, comprising electroplating the surface of a conductive substrate at a rate such that the metal particles form on the conductive substrate faster than necessary to form shiny platinum and slower than necessary to form platinum black.Type: GrantFiled: August 17, 2006Date of Patent: August 13, 2019Assignee: Second Sight Medical Products, Inc.Inventor: Dao Min Zhou
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Patent number: 10188853Abstract: The present invention is a flexible circuit electrode array with a polymer base layer, metal traces deposited on the polymer base layer, including electrodes suitable to stimulate neural tissue, a polymer top layer deposited on the polymer base layer and the metal traces, and a soft polymer filling a void through both the polymer base layer and polymer top layer, the soft polymer forming drum stress relief around an attachment point.Type: GrantFiled: March 7, 2008Date of Patent: January 29, 2019Assignee: Second Sight Medical Products, Inc.Inventors: Rajat Agrawal, Robert J. Greenberg, Mark S. Humayun, James Singleton Little, Brian V. Mech, Jordan Matthew Neysmith, Neil Hamilton Talbot, Dao Min Zhou
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Patent number: 10159832Abstract: The present invention provides an implantable electrode with increased stability wherein the surface is of the electrode comprises mesh grids which are filled with sticks which are filed with a conducting or insulating material. The present invention further provides a method of manufacturing an electrode with increased stability, comprising: depositing a metal layer on an base layer; applying photoresist layer on the metal layer; patterning the photoresist layer providing openings; electroplating the openings with metal; removing the photoresist layer leaving spaces; and filling the spaces with polymer.Type: GrantFiled: October 26, 2007Date of Patent: December 25, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Dao Min Zhou, Jerry Ok, Neil Hamilton Talbot, Brian V. Mech, James Singleton Little, Robert J. Greenberg
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Patent number: 10159845Abstract: The invention is directed to a method of bonding a hermetically sealed electronics package to an electrode or a flexible circuit and the resulting electronics package that is suitable for implantation in living tissue, for a retinal or cortical electrode array to enable restoration of sight to certain non-sighted individuals. The hermetically sealed electronics package is directly bonded to the flex circuit or electrode by electroplating a biocompatible material, such as platinum or gold, effectively forming a plated rivet-shaped connection, which bonds the flex circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation in living tissue.Type: GrantFiled: November 13, 2015Date of Patent: December 25, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Robert J. Greenberg, Alfred E. Mann, Dao Min Zhou, Neil Talbot, Jerry Ok, Gailland R. Nolan
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Patent number: 10065036Abstract: The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.Type: GrantFiled: September 28, 2007Date of Patent: September 4, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Amy Chu Peishuan Hines, Dao Min Zhou, Arup Roy, Rongqing Dai, Robert J. Greenberg
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Patent number: 9974953Abstract: An apparatus for controlling the stimulation of neural tissue which includes a neural stimulator, an input device for providing input to the neural stimulator for neural stimulation, at least one electrode electrically connected to and driven by the neural stimulator and suitable to stimulate neural tissue, a device capable of determining a charge per phase by calculating a discrete integral of the wave form of the input for the at least one electrode, a calculating device for comparing the charge per phase to a predetermined maximum and determining a reduced stimulation for the at least one electrode by the amount necessary not to exceed the predetermined maximum for the at least one electrode, and a current pulse generator for stimulating the neural tissue according to the reduced stimulation level.Type: GrantFiled: March 26, 2012Date of Patent: May 22, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Robert Jay Greenberg, Kelly Hobart McClure, James Singleton Little, Rongqing Dai, Arup Roy, Richard Agustin Castro, John Reinhold, Kea-Tiong Tang, Sumit Yadav, Chunhong Zhou, Dao Min Zhou, Pishoy Maksy
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Patent number: 9913985Abstract: In electrically stimulating neural tissue it is important to prevent over stimulation and unbalanced stimulation which would cause damage to the neural tissue, the electrode, or both. It is critical that neural tissue in not subjected to any direct current or alternating current above a safe threshold. Further, it is important to identify defective electrodes as continued use may result in neural and further electrode damage. The present invention presents system and stimulator control mechanisms to prevent damage to neural tissue.Type: GrantFiled: April 28, 2006Date of Patent: March 13, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Robert Jay Greenberg, Kelly Hobart McClure, James Singleton Little, Rongqing Dai, Arup Roy, Richard Agustin Castro, John Reinhold, Kea-Tiong Tang, Sumit Yadav, Chunhong Zhou, Dao Min Zhou, Pishoy Maksy
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Patent number: 9861820Abstract: The present invention consists of an implantable device with a hermetic electronics package that houses electronics. The hermetic package is attached to a flexible circuit electrode array having its electrodes arranged in a trapezoidal electrode array field that is suitable to stimulate the visual cortex. The hermetic electronics package is provided with a fixation structure that secures, protects and dissipates heat from the electronics package. The entire implantable device can be entirely implanted within the head.Type: GrantFiled: May 13, 2016Date of Patent: January 9, 2018Assignee: Second Sight Medical Products, Inc.Inventors: Robert J. Greenberg, Neil Talbot, Proyag Datta, Dustin Tobey, Dao Min Zhou, Jessy Dorn
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Patent number: 9802045Abstract: The present invention is a method for measuring stable and reproducible electrode-tissue impedance, comprising preconditioning an electrode-tissue interface. Further aspect of the invention is a stimulation system for a visual prosthesis generating a stimulation signal to precondition the electrode-tissue interface, comprising a computer; software, loaded in the computer, adapted to perform a stimulating method for a visual prosthesis having a plurality of electrodes; a video processing unit; and an implanted neuron-stimulator.Type: GrantFiled: October 25, 2007Date of Patent: October 31, 2017Assignee: Second Sight Medical Products, Inc.Inventors: Amy Chu Peishuan Hines, Dao Min Zhou, Arup Roy, Rongqing Dai, Robert J. Greenberg
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Patent number: 9669209Abstract: A flexible circuit electrode array with more than one layer of metal traces comprising: a polymer base layer; more than one layer of metal traces, separated by polymer layers, deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; and a polymer top layer deposited on said polymer base layer and said metal traces. Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow.Type: GrantFiled: April 18, 2016Date of Patent: June 6, 2017Assignee: Second Sight Medical Products, Inc.Inventors: Jordan Neysmith, Robert Greenberg, James Little, Brian Mech, Neil Talbot, Qingfang Yao, Dao Min Zhou
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Patent number: 9597495Abstract: The invention is a method of identifying a preferred location for an electrode array to the neural characteristics of an individual subject. The response to electrical neural stimulation varies from subject to subject and array location to array location. Measure of impedance may be used to predict the electrode height from the neural tissue and, thereby, predict the preferred location. Alternatively, electrode height may be measured directly to predict the preferred location.Type: GrantFiled: April 20, 2012Date of Patent: March 21, 2017Assignee: Second Sight Medical Products, Inc.Inventors: Robert J. Greenberg, Jone Fine, Arup Roy, Matthew J. McMahon, Mark S. Humayun, James David Welland, Alan M. Horsager, Dao Min Zhou, Amy Hines, Sumit Yadav, Rongqing Dai
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Publication number: 20160331968Abstract: The present invention consists of an implantable device with a hermetic electronics package that houses electronics. The hermetic package is attached to a flexible circuit electrode array having its electrodes arranged in a trapezoidal electrode array field that is suitable to stimulate the visual cortex. The hermetic electronics package is provided with a fixation structure that secures, protects and dissipates heat from the electronics package. The entire implantable device can be entirely implanted within the head.Type: ApplicationFiled: May 13, 2016Publication date: November 17, 2016Applicant: SECOND SIGHT MEDICAL PRODUCTS, INC.Inventors: Robert J. Greenberg, Neil Talbot, Proyag Datta, Dustin Tobey, Dao Min Zhou, Jessy Dorn
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Publication number: 20160228695Abstract: A flexible circuit electrode array with more than one layer of metal traces comprising: a polymer base layer; more than one layer of metal traces, separated by polymer layers, deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; and a polymer top layer deposited on said polymer base layer and said metal traces. Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow.Type: ApplicationFiled: April 18, 2016Publication date: August 11, 2016Applicant: Second Sight Medical Products, Inc.Inventors: Jordan Neysmith, Robert Greenberg, James Little, Brian Mech, Neil Talbot, Qingfang Yao, Dao Min Zhou
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Publication number: 20160158559Abstract: The invention is directed to a method of bonding a hermetically sealed electronics package to an electrode or a flexible circuit and the resulting electronics package that is suitable for implantation in living tissue, for a retinal or cortical electrode array to enable restoration of sight to certain non-sighted individuals. The hermetically sealed electronics package is directly bonded to the flex circuit or electrode by electroplating a biocompatible material, such as platinum or gold, effectively forming a plated rivet-shaped connection, which bonds the flex circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation in living tissue.Type: ApplicationFiled: November 13, 2015Publication date: June 9, 2016Inventors: Robert J. Greenberg, Alfred E. Mann, Dao Min Zhou, Neil Talbot, Jerry Ok, Gailland R. Nolan
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Patent number: 9314615Abstract: A flexible circuit electrode array with more than one layer of metal traces comprising: a polymer base layer; more than one layer of metal traces, separated by polymer layers, deposited on said polymer base layer, including electrodes suitable to stimulate neural tissue; and a polymer top layer deposited on said polymer base layer and said metal traces. Polymer materials are useful as electrode array bodies for neural stimulation. They are particularly useful for retinal stimulation to create artificial vision, cochlear stimulation to create artificial hearing, or cortical stimulation many purposes. The pressure applied against the retina, or other neural tissue, by an electrode array is critical. Too little pressure causes increased electrical resistance, along with electric field dispersion. Too much pressure may block blood flow.Type: GrantFiled: March 16, 2012Date of Patent: April 19, 2016Assignee: Second Sight Medical Products, Inc.Inventors: Jordan Matthew Neysmith, Neil Hamilton Talbot, James Singleton Little, Brian V. Mech, Robert J. Greenberg, Qingfang Yao, Dao Min Zhou
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Patent number: 9220169Abstract: Device is a hermetically sealed electronics package bonded to an electrode or flexible circuit that is suitable for implantation such as for a retinal or cortical electrode array. The hermetically sealed electronics package is bonded to the electrode or flexible circuit by electroplating a biocompatible material, such as platinum or gold, forming a plated connection, bonding the flexible circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation. The device comprises a substrate containing a contact, a flexible assembly containing a pad, and electroplated bonding between said contact and said pad that bonds said substrate and said flexible assembly together.Type: GrantFiled: June 21, 2007Date of Patent: December 22, 2015Assignee: Second Sight Medical Products, Inc.Inventors: Dao Min Zhou, James Singleton Little, Robert J. Greenberg
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Patent number: 8880165Abstract: The invention is directed to a method of bonding a hermetically sealed electronics package to an electrode or a flexible circuit and the resulting electronics package, that is suitable for implantation in living tissue, such as for a retinal or cortical electrode array to enable restoration of sight to certain non-sighted individuals. The hermetically sealed electronics package is directly bonded to the flex circuit or electrode by electroplating a biocompatible material, such as platinum or gold, effectively forming a plated rivet-shaped connection, which bonds the flex circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation in living tissue.Type: GrantFiled: January 19, 2011Date of Patent: November 4, 2014Inventors: Robert J. Greenberg, Neil Talbot, Jerry Ok, Jordan Neysmith, Dao Min Zhou
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Patent number: 8571671Abstract: A critical element of a retinal prosthesis is the stimulating electrode array, which is placed in close proximity to the retina. It is via this interface that a retinal prosthesis electrically stimulates nerve cells to produce the perception of light. The impedance load seen by the current driver consists of the tissue resistance and the complex electrode impedance. The results show that the tissue resistance of the retina is significantly greater than that of the vitreous humor in the eye. Circuit models of the electrode-retina interface are used to parameterize the different contributors to the overall impedance.Type: GrantFiled: July 2, 2012Date of Patent: October 29, 2013Assignee: Second Sight Medical Products, Inc.Inventors: Samip Shah, Amy Chu Peishuan Hines, Dao Min Zhou, Robert J. Greenberg, Mark S. Humayun, James D. Weiland
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Patent number: 8548597Abstract: Methods and devices for inductively coupled implants on the human or animal body are disclosed. An external coil assembly to be used with the implant has a transmitting coil and one or more receiving coils. The number of the receiving coils, their distance from the transmitting coil and their shape is chosen to reduce the influence of a noise signal received by the external coil assembly.Type: GrantFiled: September 29, 2006Date of Patent: October 1, 2013Assignee: Second Sight Medical Products, Inc.Inventors: Rongqing Dai, Dao Min Zhou, Robert J. Greenberg, John Gord
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Patent number: 8440060Abstract: An electrode surface coating for manufacturing the electrode surface coating comprising a conductive substrate; and one or more surface coatings comprising one or more of the following metals titanium, niobium, tantalum, ruthenium, rhodium, iridium, palladium, or gold, or an alloy of two or more metals, or a combination of two or more alloys or metal layers thereof having an increase in the surface area of 5 times to 500 times of the corresponding surface area resulting from the basic geometric shape.Type: GrantFiled: July 29, 2008Date of Patent: May 14, 2013Assignee: Second Sight Medical Products, Inc.Inventor: Dao Min Zhou