Abstract: A method of treating mild to moderate psoriasis in a patient administers an IL-23 specific antibody, e.g., guselkumab, at an initial dose and subsequent doses in order for the patient to respond to the antibody and meet one or more of the clinical endpoints.

Abstract: A method of treating Crohn's disease in a patient administers an IL-23 specific antibody, e.g., guselkumab, at an initial intravenous dose and subsequent subcutaneous doses in order for the patient to respond to the antibody and meet one or more of the clinical endpoints.

Abstract: A method of treating Crohn's disease in a patient administers an IL-23 specific antibody, e.g., guselkumab, at an initial intravenous dose and subsequent subcutaneous doses in order for the patient to respond to the antibody and meet one or more of the clinical endpoints.

Abstract: A method of treating Crohn's disease in a patient administers an IL-23 specific antibody, e.g., guselkumab, at an initial intravenous dose and subsequence subcutaneous doses.

Abstract: A method of treating Crohn's disease in a patient administers an IL-23 specific antibody, e.g., guselkumab, at an initial intravenous dose and subsequence subcutaneous doses.

Abstract: The present invention is an anti-drip showerhead which includes a body, a cover plate and a plurality of spray outlets opened on the cover plate. Each of the spray outlets comprises an anti-drip means chamber at a first end and at least one spray outlet opening at a second end opposite the first end; the anti-drip means chamber and the spray outlet opening are in water communication with each other; each of the anti-drip means chambers is disposed with a water pressure actuated anti-drip means which is operable between an open position where water from the body is allowed to pass through the anti-drip means and exits through the spray outlet opening and a close position where water from the body is blocked by the anti-drip means and thus could not exit through the spray outlet opening.