Patents by Inventor Daqiang Xu

Daqiang Xu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives
    Patent number: 7115662
    Abstract: Disclosed are the compounds of formula I wherein R is methyl or ethyl; R1 is chloro or fluoro; R2 is hydrogen or fluoro; R3 is hydrogen, fluoro, chloro, methyl, ethyl, methoxy, ethoxy or hydroxy; R4 is hydrogen or fluoro; and R5 is chloro, fluoro, trifluoromethyl or methyl; and pharmaceutically acceptable salts thereof, as selective COX-2 cyclooxygenase inhibitors; and pharmaceutically acceptable prodrug esters thereof.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: October 3, 2006
    Assignee: Novartis AG
    Inventors: Roger A Fujimoto, Leslie W McQuire, Benjamin B Mugrage, John H Van Duzer, Daqiang Xu
  • Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives
    Publication number: 20040122254
    Abstract: Disclosed are the compounds of formula I 1
    Type: Application
    Filed: December 4, 2003
    Publication date: June 24, 2004
    Inventors: Roger A. Fujimoto, Leslie W. McQuire, Benjamin B. Mugrage, John H. Van Duzer, Daqiang Xu
  • Process for preparing certain substituted caprolactams
    Patent number: 6545148
    Abstract: The present invention relates to an improved process for preparing certain substituted caprolactam compounds which comprises acylating an aminocaprolactam compound with a lactone compound in the presence of a weak base and a polar, organic solvent, and hydrolyzing the resultant diamide compound in a mixture of solvents to obtain the desired caprolactam compound.
    Type: Grant
    Filed: March 11, 2002
    Date of Patent: April 8, 2003
    Assignee: Novartis AG
    Inventors: David Daqiang Xu, Wenming Liu
  • Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives
    Publication number: 20020183391
    Abstract: Disclosed are the compounds of formula I 1
    Type: Application
    Filed: July 23, 2002
    Publication date: December 5, 2002
    Inventors: Roger A. Fujimoto, Leslie W. McQuire, Benjamin B. Mugrage, John H. Van Duzer, Daqiang Xu
  • Process for preparing certain substituted caprolactams
    Publication number: 20020128474
    Abstract: The present invention relates to an improved process for preparing certain substituted caprolactam compounds which comprises acylating an aminocaprolactam compound with a lactone compound in the presence of a weak base and a polar, organic solvent, and hydrolyzing the resultant diamide compound in a mixture of solvents to obtain the desired caprolactam compound.
    Type: Application
    Filed: March 11, 2002
    Publication date: September 12, 2002
    Inventors: David Daqiang Xu, Wenming Liu
  • Certain 5-alkyl-2arylaminophenylacetic acids and derivatives
    Publication number: 20020013369
    Abstract: Disclosed are the compounds of formula I 1
    Type: Application
    Filed: September 13, 2001
    Publication date: January 31, 2002
    Inventors: Roger A. Fujimoto, Leslie W. McQuire, Benjamin B. Mugrage, John H. van Duzer, Daqiang Xu
  • Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives
    Patent number: 6310099
    Abstract: Disclosed are the compounds of formula I wherein R is methyl or ethyl; R1 is chloro or fluoro; R2 is hydrogen or fluoro; R3 is hydrogen, fluoro, chloro, methyl, ethyl, methoxy, ethoxy or hydroxy; R4 is hydrogen or fluoro; and R5 is chloro, fluoro, trifluoromethyl or methyl; and pharmaceutically acceptable salts thereof, as selective COX-2 cyclooxygenase inhibitors; and pharmaceutically acceptable prodrug esters thereof.
    Type: Grant
    Filed: November 27, 2000
    Date of Patent: October 30, 2001
    Assignee: Novartis Ag
    Inventors: Roger A. Fujimoto, Leslie W. McQuire, Benjamin B. Mugrage, John H. van Duzer, Daqiang Xu
  • Certain 5-alkyl-2-arylaminophenylacetic acids and derivatives
    Patent number: 6291523
    Abstract: Disclosed are the compounds of formula I wherein R is methyl or ethyl; R1 is chloro or fluoro; R2 is hydrogen or fluoro; R3 is hydrogen, fluoro, chloro, methyl, ethyl, methoxy, ethoxy or hydroxy; R4 is hydrogen or fluoro; and R5 is chloro, fluoro, trifluoromethyl or methyl; and pharmaceutically acceptable salts thereof, as selective COX-2 cyclooxygenase inhibitors; and pharmaceutically acceptable prodrug esters thereof.
    Type: Grant
    Filed: August 25, 1998
    Date of Patent: September 18, 2001
    Assignee: Novartis AG
    Inventors: Roger A. Fujimoto, Leslie W. McQuire, Benjamin B. Mugrage, John H. van Duzer, Daqiang Xu