Abstract: Embodiments include systems for sequencing a biological sample. The system may include a reusable subsystem and a removable subsystem. The reusable subsystem may actuate and operate the removable subsystem to automate the sequencing. A base unit of the reusable subsystem may form a fluidic connection between an integrated reagent cartridge and an integrated sensor cartridge of the removable subsystem. The integrated reagent cartridge may be configured to hold reagents and the integrated sensor cartridge may be configured with a biosensor for sequencing the biological sample.

Abstract: The application disclose an antenna. The antenna includes a first radiating element, a second radiating element, a third radiating element, and a closed ring, where the first radiating element is connected to a first feed point, the second radiating element is connected to a second feed point, and the third radiating element is connected to a third feed point; the closed ring is configured to be disposed in a clearance area of a ground plate, and configured to connect to the ground plate; the first radiating element, the second radiating element, and the third radiating element are connected by using a microstrip, to form a radiator; the third radiating element is disposed between the first radiating element and the second radiating element.

Abstract: The application disclose an antenna. The antenna includes a first radiating element, a second radiating element, a third radiating element, and a closed ring, where the first radiating element is connected to a first feed point, the second radiating element is connected to a second feed point, and the third radiating element is connected to a third feed point; the closed ring is configured to be disposed in a clearance area of a ground plate, and configured to connect to the ground plate; the first radiating element, the second radiating element, and the third radiating element are connected by using a microstrip, to form a radiator; the third radiating element is disposed between the first radiating element and the second radiating element.

Abstract: The present invention relates to a therapeutic knee brace system including a leg brace for support, a retainer for securing the therapeutic knee brace system to a knee joint therapy site, a brace joint providing a limited range of flexion to the knee brace, and an active thermal exchange bladder coupled to a contrast therapy system for delivering a therapy fluid at a select temperature, pressure and rate. Thermal exchange bladder is removable, and the pressure may be constant or dynamic. The angle of flexion may be selected by the therapy recipient, and the range of flexion of the brace joint is configurable. The knee brace may communicate range and instant angle of flexion of the brace joint to a continuous passive motion (CPM) device, and communication may be mechanical, electronic or wireless. A knee brace coupler attaches to a CPM coupler on the CPM device to selectively couple the therapeutic knee brace system to the CPM device.

Abstract: The present invention relates to a therapeutic cranial wrap for use with a thermal contrast therapy systems and methods for providing a temperature regulated fluid. The cranial wrap includes an active thermal exchange bladder and an active compression bladder, adapted to fit the cranial therapy site. The thermal exchange bladder may be coupled to the thermal contrast therapy system. The compression bladder may compress the therapy site. In some embodiments, the compressive bladder may be integrated into the thermal exchange bladder, or may be omitted. The cranial wrap also includes a contoured shell, known as a hood shaped therapy pad, which is adapted to snugly fit the cranial therapy site and provide neck support. Adjustable straps, including at least one strap that circumvents the cranium, secure the cranial wrap in a fitted position adjacent the therapy site. The cranial wrap couples to the thermal contrast therapy system which includes a hot and cold fluid reservoir, a mixing valve, and a fluid pump.

Abstract: The present invention relates to a therapeutic spinal column brace system, comprising an active thermal exchange layer for providing thermal contrast therapy to a therapy site, an active compression bladder for providing compression to the therapy site, at least one cushion layer for comfort, a rigid shell including at least one rigid support brace, and an adjustable strapping system to secure the therapeutic spinal column brace system to the spinal column therapy site. In some embodiment an active amalgamated bladder or a thermal exchange and compression bladder may be used in lieu of the thermal exchange bladder and the compression bladder. By regulating the pressure within the bladders the compression may be steady or pulsating to achieve a therapeutic effect. A contrast therapy system comprising a hot reservoir, a cold reservoir, a mixing valve, and a fluid pump for delivering the therapy fluid to the therapeutic spinal column brace system may be utilized.

Abstract: The present invention relates to fluid mixing valves, and more particularly, to mixing valve assemblies which incorporate a ball element and which are adapted for use in a thermal or contrast therapy system, or medical thermal therapy system. The ball element of the present invention is characterized by continuously varying restrictive inlets which enable the user to obtain a substantially linear therapy temperature profile while maintaining substantially constant outlet pressure and flow rates.

Abstract: The fluid coupler comprises a male coupler, a female coupler, and a seal between the male coupler and the female coupler when they are coupled, preventing fluid leakage. The female coupler receives the male coupler when in a coupled position. The male coupler includes a two pieced housing, a unitary valve and a biasing member. The two pieces of the housing may be joined. A cavity runs the length of the housing. The female coupler includes a housing, an annulus, a unitary valve and a biasing member. The annulus and the housing may be joined. A cavity runs the length of the housing. The unitary valves and biasing members fit within the cavities and are capable of longitudinal positioning within a configurable range. When male coupler and female coupler are coupled, the unitary valves are open permitting fluid flow. Otherwise, if uncoupled, the unitary valves are closed preventing fluid leakage.

Abstract: The present invention relates to a therapeutic cranial wrap for use with a thermal contrast therapy systems and methods for providing a temperature regulated fluid. The cranial wrap includes an active thermal exchange bladder and an active compression bladder, adapted to fit the cranial therapy site. The thermal exchange bladder may be coupled to the thermal contrast therapy system. The compression bladder may compress the therapy site. In some embodiments, the compressive bladder may be integrated into the thermal exchange bladder, or may be omitted. The cranial wrap also includes a contoured shell, known as a hood shaped therapy pad, which is adapted to snugly fit the cranial therapy site and provide neck support. Adjustable straps, including at least one strap that circumvents the cranium, secure the cranial wrap in a fitted position adjacent the therapy site. The cranial wrap couples to the thermal contrast therapy system which includes a hot and cold fluid reservoir, a mixing valve, and a fluid pump.