Abstract: Described herein are small molecule cap-dependent inhibitors, including the compound of the formula: which compounds that can induce the accumulation of the p53 tumor suppressor protein in cancer cells that still express wild-type p53, as well as methods of using those compounds to, among other things, treat neuroblastoma, pediatric glioblastoma multiforme or breast cancer.

Abstract: Described herein are compounds pharmaceutically acceptable salts, isomers, mixture of isomers, crystalline forms, non-crystalline forms, hydrates, or solvates thereof, as well as methods using those compounds to, among other things, treat cancer.

Abstract: An anti-theft device for smart wearable gears display includes: a clamping device, a connection port and a thin sensor configured to connect with the clamping device and the product. The clamping device includes a top fixture and a bottom fixture, wherein the top and bottom fixtures are rotatably connected on one side and removably connected on the other side. A passage slot is formed between the inner facing surfaces of the top and bottom fixtures, which are used to accommodate a connection band of the displayed product. The bottom fixture includes a contact switch. The thin sensor and the contact switch are both electrically connected to the connection port, and the connection port is electrically connected to the controller.