Patents by Inventor Darcy Madden, legal representative

Darcy Madden, legal representative has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleic acids encoding nitrilases
    Patent number: 8334125
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: December 18, 2012
    Assignee: Verenium Corporation
    Inventors: Grace DeSantis, Ellen Chi, Jennifer Ann Chaplin, Aileen Milan, Jay Short, David Weiner, Mark Madden, Darcy Madden, legal representative, Mark Burk, Dan Robertson
  • Nitrilases
    Patent number: 7651849
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: January 26, 2010
    Inventors: Grace DeSantis, Ellen Chi, Jennifer Ann Chaplin, Aileen Milan, Jay M. Short, David Paul Weiner, Mark Madden, Darcy Madden, legal representative, Mark J. Burk, Dan E. Robertson
  • Nitrilases and methods for making and using them
    Patent number: 7521216
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: April 21, 2009
    Assignee: Verenium Corporation
    Inventors: Grace DeSantis, Jennifer Ann Chaplin, Ellen Chi, Aileen Milan, Jay M. Short, David Weiner, Darcy Madden, legal representative, Mark J. Burk, Dan E. Robertson, Mark Madden
  • Methods for producing ?-substituted carboxylic acids using nitrilases and strecker reagents
    Patent number: 7300775
    Abstract: In accordance with the present invention there are provided methods for producing enantiomerically pure ?-substituted carboxylic acids, such as, for example, ?-amino acids and ?-hydroxy acids, said method comprising combining an aldehyde or ketone with a cyanide and ammonia or an anmionium salt or an amine, in the presence of a nitrilase or a polypeptide having nitrilase activity which stereoselectively hydrolyzes the amino nitrile or cyanohydrin intermediate under conditions sufficient to produce the enantiomerically pure ?-substituted carboxylic acid, such as, for example, ?-amino acids and ?-hydroxy acids.
    Type: Grant
    Filed: December 28, 2000
    Date of Patent: November 27, 2007
    Assignee: Verenium Corporation
    Inventors: Darcy Madden, legal representative, David Paul Weiner, Jennifer Ann Chaplin, Dan E. Robertson, Mark Madden, deceased