Patents by Inventor Darin Allen

Darin Allen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of preparing toll-like receptor modulators
    Patent number: 9573952
    Abstract: The present invention provides methods of preparing 4-amino-2-butoxy-8-(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one and related compounds.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: February 21, 2017
    Assignee: Gilead Sciences, Inc.
    Inventors: Darin Allen, Brandon Heath Brown, Jessica Jade Chao, Randall L. Halcomb, Paul Hrvatin, Ryan McFadden, Paul Roethle, Erwina Rudio, Hong Yang, Richard Hung Chiu Yu
  • METHODS OF PREPARING TOLL-LIKE RECEPTOR MODULATORS
    Publication number: 20160075707
    Abstract: The present invention provides methods of preparing 4-amino-2-butoxy-8-(3-(pyrrolidin-1-ylmethyl)benzyl)-7,8-dihydropteridin-6(5H)-one and related compounds.
    Type: Application
    Filed: September 14, 2015
    Publication date: March 17, 2016
    Inventors: Darin Allen, Brandon Heath Brown, Jessica Jade Chao, Randall L. Halcomb, Paul Hrvatin, Ryan McFadden, Paul Roethle, Erwina Rudio, Hong Yang, Richard Hung Chiu Yu
  • MONOCYCLIC AMINOPROPYL TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S
    Publication number: 20090118274
    Abstract: Monocyclic aminopropyl tetrahydro-pyrazolo-pyridine compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.
    Type: Application
    Filed: February 14, 2008
    Publication date: May 7, 2009
    Inventors: Darin Allen, Michael K. Ameriks, Frank U. Axe, Matthew Burdett, Hui Cai, Ingrid Choong, James P. Edwards, Willard Lew, Steven P. Meduna
  • BICYCLIC AMINOPROPYL TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S
    Publication number: 20080269241
    Abstract: Bicyclic aminopropyl tetrahydro-pyrazolo-pyridine compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.
    Type: Application
    Filed: February 14, 2008
    Publication date: October 30, 2008
    Inventors: Darin Allen, Michael K. Ameriks, Frank U. Axe, Matthew Burdett, Hui Cai, Ingrid Choong, James P. Edwards, Willard Lew, Steven P. Meduna
  • BIARYL-SUBSTITUTED TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S
    Publication number: 20080207683
    Abstract: Biaryl-substituted tetrahydro-pyrazolo-pyridine compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.
    Type: Application
    Filed: February 14, 2008
    Publication date: August 28, 2008
    Inventors: Darin Allen, Ingrid Choong, Willard Lew
  • Caspase-1 inhibitors and methods for their use
    Patent number: 7115654
    Abstract: The invention provides compounds of Formula I and derivatives thereof, pharmaceutical compositions comprising a compound of Formula I, and methods of treatment utilizing such compounds and compositions: wherein: R1 is chosen from optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, and optionally substituted heteroaralkyl; L is a linker; R2 is chosen from optionally substituted aryl, optionally substituted aralkyl, optionally substituted heteroaryl, and optionally substituted heteroaralkyl; and or single stereoisomers, mixtures of stereoisomers, or the pharmaceutically acceptable salts, amides, or esters thereof.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: October 3, 2006
    Assignee: Sunesis Pharmaceuticals, Inc.
    Inventors: Darin Allen, Bruce Fahr, Johan Oslob, Brian C. Raimundo, Michael J. Romanowski
  • Caspase-1 inhibitors and methods for their use
    Publication number: 20040048895
    Abstract: The invention provides compounds of Formula I and derivatives thereof, pharmaceutical compositions comprising a compound of Formula I, and methods of treatment utilizing such compounds and compositions: 1
    Type: Application
    Filed: June 5, 2003
    Publication date: March 11, 2004
    Inventors: Darin Allen, Bruce Fahr, Johan Oslob, Brian C. Raimundo, Michael J. Romanowski