Abstract: A System Platform establishes a Genuine User ID (“GUID”), creates a user profile for an Intended User, generates a unique data set based upon input associated with the user profile and a digital device it has registered to the Intended User. The output of the GUID in combination with the output of an algorithm in a provisioning application enables the digital device to respond to Access Requests at an Access Point. The response from the genuine Intended User's application on their genuine digital device produces a unique data package which combines the GUID, a device ID for the digital device and the output of the algorithm using the payload obtained from one or more data management sources. The unique data package can be tailored for many different uses by the intended user, including uses which are attended or unattended, with varying levels of security.

Abstract: A System Platform establishes a Genuine User ID (“GUID”) (based upon input received from an Identity Management Source), creates a user profile for an Intended User, generates a unique data set based upon input associated with the user profile and a digital device it has registered to the Intended User, which is securely provisioned on the digital device. The output of the GUID in combination with the output of an algorithm in a provisioning application enables the digital device to respond to Access Requests at an Access Point. The response from the genuine Intended User's application on their genuine digital device produces a unique data package which combines the GUID, a device ID for the digital device and the output of the algorithm using the payload obtained from one or more data management sources.

Abstract: A method includes directing toward a portion of a subject's body a first pulse of electromagnetic energy. While the portion is in a functional state due to the first pulse, a second pulse is directed toward the portion. At a second-pulse time, reflected energy due to the second pulse is detected. While the portion is in a functional state due to the first and second pulses, a third pulse is directed toward the portion. At a third-pulse time, energy of the third pulse, reflected from the portion, is detected. In response to detecting the pulses at the second-pulse time and the third-pulse time, a characteristic of the portion is quantified resulting from (a) the functional state due to the first pulse and (b) the functional state due to the first and second pulses. A clinical state of the subject is identified. Other embodiments are described.

Abstract: Apparatus (2) is provided, including a heartbeat measurement device (3), which senses a cardiac parameter of a patient and generates a cardiac parameter signal responsively thereto. An optical measurement device acquires data by emitting towards tissue of the patient 400-1000 niti light, and receiving light reflected from the tissue. An integrator unit (10) receives the cardiac parameter signal and, in response thereto, actuates the optical measurement device to acquire the data.

Abstract: A method and system for determination and mapping the quantity of chromophores having a distinct spectrum attached to moving objects in an spectrally rich environment that may include multiple chromophores attached to stationary objects. Au area of interest is imaged at different times and different wavelengths, and the spectral properties of the chromophores attached to the moving objects are separated from the stationary spectral properties of the background, followed by spectral analysis of the moving objects to determine their quantity. Application to the retinal vasculature is illustrated, showing the imaging, analyzing and quantifying of the oxygen saturation of retinal blood, resolved for the different vascular compartments, including capillaries, arterioles, venules, arteries, and veins.

Abstract: Apparatus (2) is provided, including a heartbeat measurement device (3), which senses a cardiac parameter of a patient and generates a cardiac parameter signal responsively thereto. An optical measurement device acquires data by emitting towards tissue of the patient 400-1000 niti light, and receiving light reflected from the tissue. An integrator unit (10) receives the cardiac parameter signal and, in response thereto, actuates the optical measurement device to acquire the data.

Abstract: A method includes directing toward a portion of a subject's body a first pulse of electromagnetic energy. While the portion is in a functional state due to the first pulse, a second pulse is directed toward the portion. At a second-pulse time, reflected energy due to the second pulse is detected. While the portion is in a functional state due to the first and second pulses, a third pulse is directed toward the portion. At a third-pulse time, energy of the third pulse, reflected from the portion, is detected. In response to detecting the pulses at the second-pulse time and the third-pulse time, a characteristic of the portion is quantified resulting from (a) the functional state due to the first pulse and (b) the functional state due to the first and second pulses. A clinical state of the subject is identified. Other embodiments are described.

Abstract: A method and system for determination and mapping the quantity of chromophores having a distinct spectrum attached to moving objects in an spectrally rich environment that may include multiple chromophores attached to stationary objects. An area of inters is imaged at different times and different wavelengths, and the spectral properties of the or more chromophores attached to the moving objects are separated from the stationary spectral properties of the background, followed by spectral analysis of the moving objects to determine their quantity. Application to the retinal vasculature is illustrated, showing the imaging, analyzing and quantifying of the oxygen saturation of retinal blood, resolved for the different vascular compartments—capillaries, arterioles, venules, arteries, and veins.

Abstract: A method and system for determination and mapping the quantity of chromophores having a distinct spectrum attached to moving objects in an spectrally rich environment that may include multiple chromophores attached to stationary objects. An area of inters is imaged at different times and different wavelengths, and the spectral properties of the or more chromophores attached to the moving objects are separated from the stationary spectral properties of the background, followed by spectral analysis of the moving objects to determine their quantity. Application to the retinal vasculature is illustrated, showing the imaging, analyzing and quantifying of the oxygen saturation of retinal blood, resolved for the different vascular compartments—capillaries, arterioles, venules, arteries, and veins.

Abstract: The invention provides a system for directly imaging and analyzing the movement of individual erythrocytes in blood vessels, the system comprising imaging means (4, 26) for acquiring, within a predetermined time interval from each other, at least one pair of images of at least one same erythrocyte for producing at least two frames, each image representing an analog or digital image of the location of the erythrocyte in each of the frames at a predetermined time; image acquisition means (12) for collecting and storing analog or digital images in machine-readable form, and a computer (10) for controlling the operation of the imaging means and the image acquisition means, for processing the at least two frames, and for analyzing the movement of the erythrocyte in the blood vessels. A method for directly imaging and analyzing the movement of individual erythrocytes in blood vessels is also provided.

Abstract: The invention provides a system for imaging reflectance changes, intrinsic or extrinsic fluorescence changes of a retina (6) due to retinal function, including an imaging illuminator (14) for illumination of the retina (6); a retina-stimulating illuminator (2) for inducing a functional response; an imaging device (20) receiving light from the retina (6) via retinal imaging optics (12); image acquisition means (26) for digitizing and storing images received from the imaging device (20), and a computer (28) for controlling the operation of the system and for processing the stored images to reveal a differential functional signal corresponding to the retina's function.