Patents by Inventor Darin Vanderpool

Darin Vanderpool has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds, compositions, and methods for stimulating neuronal growth and elongation
    Patent number: 6544987
    Abstract: The present invention concerns methods, pharmaceutical compounds, and compositions for stimulating neuroite outgrowth in nerve cells leading to nerve regeneration. These methods, compounds and compositions inhibit rotamase enzyme activity associated with binding proteins.
    Type: Grant
    Filed: December 1, 2000
    Date of Patent: April 8, 2003
    Assignee: Pfizer Inc.
    Inventors: Chuangxing Guo, Liming Dong, Xinjun J. Hou, Darin Vanderpool, Jesus Ernest Villafranca
  • Peptide mutant of human ERAB or HADH2, its X-ray crystal structure, and materials and method for identification of inhibitors thereof
    Publication number: 20020132319
    Abstract: The identification, isolation and modification of human ERAB or HADH2 is described. A crystal structure of ERAB or HADH2 is described which may be used in the discovery, identification and characterization of inhibitors or modulators of ERAB or HADH2. This structure provides a three-dimensional description of binding sites of ERAB or HADH2 for structure-based design of inhibitors or modulators thereof as therapeutic agents, for example in the treatment of Alzheimer's disease).
    Type: Application
    Filed: August 17, 2001
    Publication date: September 19, 2002
    Inventors: Melwyn A. Abreo, Charles S. Agree, Robert M. Aust, Charles R. Kissinger, Stephen Margosiak, Jerry J. Meng, Laura A. Pelletier, Paul Abraham Rejto, Richard Edward Showalter, James Arthur Thomson, Anna Tempczyk-Russell, Darin Vanderpool, Jesus Ernesto Villafranca
  • Compounds, compositions, and methods for stimulating neuronal growth and elongation
    Publication number: 20020061881
    Abstract: The present invention concerns methods, pharmaceutical compounds, and compositions for stimulating neuroite outgrowth in nerve cells leading to nerve regeneration. These methods, compounds and compositions inhibit rotamase enzyme activity associated with binding proteins.
    Type: Application
    Filed: December 1, 2000
    Publication date: May 23, 2002
    Inventors: Chuangxing Guo, Liming Dong, Xinjun J. Hou, Darin Vanderpool, Jesus Ernest Villafranca