Patents by Inventor Dariusz Murakowski

Dariusz Murakowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIV-1 SPECIFIC IMMUNOGEN COMPOSITIONS AND METHODS OF USE
    Publication number: 20210317192
    Abstract: Disclosed herein are methods and compositions for treating a subject having or at risk of having an HIV infection. Disclosed herein are peptide immunogens and nucleic acids that have epitopes in which mutations are most likely to have deleterious effects on the HIV virus. An algorithm is disclosed for the selection of the epitopes based on the HIV fitness landscape, and it accounts for the effect of coupling mutations.
    Type: Application
    Filed: May 29, 2020
    Publication date: October 14, 2021
    Applicants: Massachusetts Institute of Technology, The General Hospital Corporation, Beth Israel Deaconess Medical Center, Inc.
    Inventors: Darrell J. Irvine, Dan H. Barouch, Arup K. Chakraborty, Dariusz Murakowski, Bruce D. Walker, John Barton, Andrew Ferguson
  • HIV-1 SPECIFIC IMMUNOGEN COMPOSITIONS AND METHODS OF USE
    Publication number: 20200377576
    Abstract: Disclosed herein are methods and compositions for treating a subject having or at risk of having an HIV infection. Disclosed herein are peptide immunogens and nucleic acids that have epitopes in which mutations are most likely to have deleterious effects on the HIV virus. An algorithm is disclosed for the selection of the epitopes based on the HIV fitness landscape, and it accounts for the effect of coupling mutations.
    Type: Application
    Filed: May 29, 2020
    Publication date: December 3, 2020
    Applicants: Massachusetts Institute of Technology, The General Hospital Corporation, Beth Israel Deaconess Medical Center, Inc.
    Inventors: Darrell J. Irvine, Dan H. Barouch, Arup K. Chakraborty, Dariusz Murakowski, Bruce D. Walker, John Barton, Andrew Ferguson