Abstract: Delivery systems and methods for deploying an implantable device are disclosed, which can include a delivery device having an outer tubular member and an inner assembly. The inner assembly is disposed within and is slidably movable relative to the outer tubular member. The inner assembly can include a pusher at a distal portion. The pusher abuts and restricts proximal movement, relative to the inner assembly, of a crimped implantable device within the outer tubular member. The pusher can include a slot to accommodate a suture binding mechanism of the implantable device. The delivery device can include a tip disposed at a distal end. The tip includes a tip transition zone. The inner sheath and outer tubular member can each have sections of distinct rigidity along their lengths with transition zones between the sections. A transition zone of the outer tubular member and a transition zone of the inner sheath can be longitudinally offset.

Abstract: Delivery systems and methods for deploying an implantable device are disclosed, which can include a delivery device having an outer tubular member and an inner assembly. The inner assembly is disposed within and is slidably movable relative to the outer tubular member. The inner assembly can include a pusher at a distal portion. The pusher abuts and restricts proximal movement, relative to the inner assembly, of a crimped implantable device within the outer tubular member. The pusher can include a slot to accommodate a suture binding mechanism of the implantable device. The delivery device can include a tip disposed at a distal end. The tip includes a tip transition zone. The inner sheath and outer tubular member can each have sections of distinct rigidity along their lengths with transition zones between the sections. A transition zone of the outer tubular member and a transition zone of the inner sheath can be longitudinally offset.

Abstract: Implantable device embodiments, such as stents, and particularly esophageal stents, formed of a scaffolding structure are disclosed. The scaffolding structure is formed of one or more strand elements arranged in a braided pattern. A covering may coat the scaffolding structure. A valve can be secured to the scaffolding structure and/or the covering. Anti-migration features may be formed by bends in the one or more strand elements. The bends forming the anti-migration features protrude outwardly away from an outer surface of the implantable device.

Abstract: Delivery systems and methods for deploying an implantable device are disclosed, which can include a delivery device having an outer tubular member and an inner assembly. The inner assembly is disposed within and is slidably movable relative to the outer tubular member. The inner assembly can include a pusher at a distal portion. The pusher abuts and restricts proximal movement, relative to the inner assembly, of a crimped implantable device within the outer tubular member. The pusher can include a slot to accommodate a suture binding mechanism of the implantable device. The delivery device can include a tip disposed at a distal end. The tip includes a tip transition zone. The inner sheath and outer tubular member can each have sections of distinct rigidity along their lengths with transition zones between the sections. A transition zone of the outer tubular member and a transition zone of the inner sheath can be longitudinally offset.

Abstract: A stent comprised of a scaffolding structure having components configured to allow at least a portion of the stent to decrease in diameter in response to an axial force applied to the stent. Further, the components and elements of the stent may be configured to balance transverse forces applied to the stent, thus reducing the incidence of infolding.

Abstract: A stent comprised of a valve and a scaffolding structure having components configured to allow at least a portion of the stent to decrease in diameter in response to an axial force applied to the stent. Further, the components and elements of the stent may be configured to balance transverse forces applied to the stent, thus reducing the incidence of infolding.

Abstract: Stent embodiments formed of a scaffolding structure are disclosed. Some embodiments may include a valve. A portion of the scaffolding structure may include a lattice structure formed by a plurality of interconnected arms arranged to form quadrilateral-shaped cells, such as diamond-shaped cells. The scaffolding structure may be formed by rows of strut arms arranged as annular segments and adjacent annular segments interconnected by connectors that extend in the longitudinal direction. The scaffolding structure may also be formed by rows of strut arms arranged in a helical pattern. The scaffolding structure has components configured to allow at least a portion of the stent to decrease in diameter in response to an axial force applied to the stent. Further, the components and elements of the stent may be configured to balance transverse forces applied to the stent, thus reducing the incidence of infolding.

Abstract: Delivery systems and methods for deploying an implantable device are disclosed, which can include a delivery device having an outer tubular member and an inner assembly. The inner assembly is disposed within and is slidably movable relative to the outer tubular member. The inner assembly can include a pusher at a distal portion. The pusher abuts and restricts proximal movement, relative to the inner assembly, of a crimped implantable device within the outer tubular member. The pusher can include a slot to accommodate a suture binding mechanism of the implantable device. The delivery device can include a tip disposed at a distal end. The tip includes a tip transition zone. The inner sheath and outer tubular member can each have sections of distinct rigidity along their lengths with transition zones between the sections. A transition zone of the outer tubular member and a transition zone of the inner sheath can be longitudinally offset.

Abstract: The embodiments disclosed herein relate to lockable syringe assemblies and related devices and methods. The syringe assembly may include a barrel, a plunger, and a locking mechanism. In some arrangements, the locking mechanism is an elastomeric locking ring or a rigid partial ring. The plunger may include a plurality of ribs and is longitudinally moveable within the barrel. Once the plunger is disposed at a desired longitudinal location, the plunger can be axially rotated and locked in such a way that further longitudinal movement is restricted.

Abstract: Various embodiments of mouthpieces for use during endoscopic procedures are disclosed herein. According to various embodiments, a mouthpiece may include a shield, a primary instrument channel, a bite block, an oxygen administration channel and a tongue depressor. The shield, bite block, oxygen administration channel and tongue depressor may be integrally formed.

Abstract: A stent comprised of a valve and a scaffolding structure having components configured to allow at least a portion of the stent to decrease in diameter in response to an axial force applied to the stent. Further, the components and elements of the stent may be configured to balance transverse forces applied to the stent, thus reducing the incidence of infolding.

Abstract: A stent comprised of a valve and a scaffolding structure having components configured to allow at least a portion of the stent to decrease in diameter in response to an axial force applied to the stent. Further, the components and elements of the stent may be configured to balance transverse forces applied to the stent, thus reducing the incidence of infolding.

Abstract: Apparatus, systems, and methods are provided for deploying an implantable device, such as a stent, within a lumen of a body of a patient. The delivery device may include an inner member and an outer sheath surrounding a distal portion of the inner member and configured to retain the implantable device sheathed near the distal end of the outer sheath until deployment. The outer sheath is slidably moveable relative to the inner member such that proximal movement of the outer sheath relative to the inner member deploys the implantable device. A trigger assembly of the delivery device can include an internal connector coupled to the outer sheath, a plurality of triggers, and a floater coupling two of the triggers. The triggers are serially retracted to deploy the stent. A panchor secures the stent against proximal and distal movement relative to the inner member during deployment.

Abstract: Implantable device embodiments, such as stents, and particularly esophageal stents, formed of a scaffolding structure are disclosed. The scaffolding structure is formed of one or more strand elements arranged in a braided pattern. A covering may coat the scaffolding structure. A valve can be secured to the scaffolding structure and/or the covering. Anti-migration features may be formed by bends in the one or more strand elements. The bends forming the anti-migration features protrude outwardly away from an outer surface of the implantable device.

Abstract: The embodiments disclosed herein relate to lockable syringe assemblies and related devices and methods. The syringe assembly may include a barrel, a plunger, and a locking mechanism. In some arrangements, the locking mechanism is an elastomeric locking ring or a rigid partial ring. The plunger may include a plurality of ribs and is longitudinally moveable within the barrel. Once the plunger is disposed at a desired longitudinal location, the plunger can be axially rotated and locked in such a way that further longitudinal movement is restricted.

Abstract: Various embodiments of mouthpieces for use during endoscopic procedures are disclosed herein. According to various embodiments, a mouthpiece may include a shield, a primary instrument channel, a bite block, an oxygen administration channel and a tongue depressor. The shield, bite block, oxygen administration channel and tongue depressor may be integrally formed.

Abstract: Various embodiments of mouthpieces for use during endoscopic procedures are disclosed herein. According to various embodiments, a mouthpiece may include a shield, a primary instrument channel, a bite block, an oxygen administration channel and a tongue depressor. The shield, bite block, oxygen administration channel and tongue depressor may be integrally formed.

Abstract: Stent embodiments formed of a scaffolding structure are disclosed. Some embodiments may include a valve. A portion of the scaffolding structure may include a lattice structure formed by a plurality of interconnected arms arranged to form quadrilateral-shaped cells, such as diamond-shaped cells. The scaffolding structure may be formed by rows of strut arms arranged as annular segments and adjacent annular segments interconnected by connectors that extend in the longitudinal direction. The scaffolding structure may also be formed by rows of strut arms arranged in a helical pattern. The scaffolding structure has components configured to allow at least a portion of the stent to decrease in diameter in response to an axial force applied to the stent. Further, the components and elements of the stent may be configured to balance transverse forces applied to the stent, thus reducing the incidence of infolding.

Abstract: A stent comprised of a valve and a scaffolding structure having components configured to allow at least a portion of the stent to decrease in diameter in response to an axial force applied to the stent. Further, the components and elements of the stent may be configured to balance transverse forces applied to the stent, thus reducing the incidence of infolding.

Abstract: Apparatus, systems, and methods are provided for deploying an implantable device, such as a stent, within a lumen of a body of a patient. The delivery device may include an inner member and an outer sheath surrounding a distal portion of the inner member and configured to retain the implantable device sheathed near the distal end of the outer sheath until deployment. The outer sheath is slidably moveable relative to the inner member such that proximal movement of the outer sheath relative to the inner member deploys the implantable device. A trigger assembly of the delivery device can include an internal connector coupled to the outer sheath, a plurality of triggers, and a floater coupling two of the triggers. The triggers are serially retracted to deploy the stent. A panchor secures the stent against proximal and distal movement relative to the inner member during deployment.