Abstract: A device for opening medicinal ampules is an apparatus to protect oneself from injury and prevent possible waste when utilizing injection medication dispensed in ampules. The device has a box type assembly with approximate dimensions of four inches wide, two inches deep and two inches high. The interior of the box is capable of holding up to three ampules at one time. The ampules are simply placed in their holding holes, and the lid is lowered. A sharp smack, administered by the user's hand and cushioned by foam padding, is adequate to snap off the neck of the ampules. The invention then serves as a holder for the ampule body while removing the medication with a syringe and for safe disposal thereafter.