Patents by Inventor Darrell C. Haynes

Darrell C. Haynes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of glycosaminoglycans to reduce non-specific binding in immunoassays
    Patent number: 8617820
    Abstract: An immunoassay reagent is provided which comprises an analyte binding agent in a diluent, and a glycosaminoglycan in an amount sufficient to reduce non-specific binding in an assay of a sample for the analyte. Provided is such an immunoassay reagent in which the analyte is troponin I, the analyte binding agent is a biotinylated anti-troponin I antibody, and the glycosaminoglycan is chondroitin sulfate. A sample composition is also provided which comprises a sample to be assayed for the presence of an analyte, an analyte binding agent, and a glycosaminoglycan other than heparin. Further provided is a method of detecting an analyte in a sample, in which non-specific binding is reduced in the method using a glycosaminoglycan.
    Type: Grant
    Filed: August 28, 2007
    Date of Patent: December 31, 2013
    Assignee: Ortho-Clinical Diagnostics, Inc.
    Inventors: Banumathi Sankaran, Sheryl S. Sullivan, Darrell C. Haynes, Philip C. Hosimer, Graham Yearwood
  • Use of Glycosaminoglycans to Reduce Non-Specific Binding in Immunoassays
    Publication number: 20090061455
    Abstract: An immunoassay reagent is provided which comprises an analyte binding agent in a diluent, and a glycosaminoglycan in an amount sufficient to reduce non-specific binding in an assay of a sample for the analyte. Provided is such an immunoassay reagent in which the analyte is troponin I, the analyte binding agent is a biotinylated anti-troponin I antibody, and the glycosaminoglycan is chondroitin sulfate. A sample composition is also provided which comprises a sample to be assayed for the presence of an analyte, an analyte binding agent, and a glycosaminoglycan other than heparin. Further provided is a method of detecting an analyte in a sample, in which non-specific binding is reduced in the method using a glycosaminoglycan.
    Type: Application
    Filed: August 28, 2007
    Publication date: March 5, 2009
    Inventors: Banumathi Sankaran, Sheryl S. Sullivan, Darrell C. Haynes, Phillp C. Hosimer, Graham Yearwood