Patents by Inventor Darrell E. O'Brien

Darrell E. O'Brien has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines
    Patent number: 4093617
    Abstract: 3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines are disclosed of the general formula ##STR1## wherein R.sub.1 is CF.sub.3 or C.sub.1 -C.sub.9 alkyl; R.sub.2 is CF.sub.3 or C.sub.1 -C.sub.9 alkyl; and R.sub.3 is halogen. Such compounds are useful as inhibitors of 3',5'-cyclic AMP phosphodiesterase enzyme.
    Type: Grant
    Filed: January 28, 1976
    Date of Patent: June 6, 1978
    Assignee: ICN Pharmaceuticals, Inc.
    Inventors: Roland K. Robins, Darrell E. O'Brien, Thomas Novinson
  • 2-Substituted-s-triazolo[1,5a]pyrimidines
    Patent number: 4036840
    Abstract: 2-Substituted-s-triazolo[1,5a]pyrimidines are disclosed which are useful as inhibitors of phosphodiesterase enzymes or intermediates in the production process. Such compounds are of the following structure: ##STR1## wherein X, R, R.sub.1, R.sub.2 and R.sub.3 are as defined hereinafter.
    Type: Grant
    Filed: May 22, 1975
    Date of Patent: July 19, 1977
    Assignee: ICN Pharmaceuticals
    Inventors: Darrell E. O'Brien, Thomas Novinson, Robert H. Springer
  • Xanthine oxidase inhibitors
    Patent number: 4021556
    Abstract: Compounds of the following structure are disclosed which are effective inhibitors of the enzyme xanthine oxidase: ##STR1## R is an aromatic or substituted aromatic nucleus such as phenyl, R.sub.1 is H, an alkali metal or ammonium, and R.sub.2 is H or OR.sub.1.
    Type: Grant
    Filed: November 17, 1975
    Date of Patent: May 3, 1977
    Assignee: ICN Pharmaceuticals, Inc.
    Inventors: Robert H. Springer, Darrell E. O'Brien, Lionel N. Simon