Abstract: The invention relates to a method of treating a cartilage matrix-forming bone tumour and/or a metastatic cancer originating from a cartilage matrix-forming bone tumour, for example chondrosarcoma, in which one or more of an inhibitor of RUNX2 activity, an inhibitor of RUNX2 expression, an inhibitor of YBX1 activity and an inhibitor of YBX1 expression, is administered to a subject in need thereof. The invention also relates to an in vitro method for detecting the presence of a cartilage matrix-forming bone tumour in a subject or the risk of a subject developing a cartilage matrix-forming bone tumour, for example chondrosarcoma, in which the following steps are performed: (i) measuring the expression level of at least one of RUNX2 and YBX1 in a biological sample obtained from a subject, and (ii) comparing the expression level of RUNX2 and/or YBX1 in the biological sample obtained from the subject with the respective expression level of RUNX2 and/or YBX1 in normal cartilage or other biological material.

Abstract: A controllable one-way clutch assembly having an electromagnetic actuator module equipped with an energizeable coil assembly, a strut moveable in response to energization of the coil assembly from a released position to a locked position, and a latching mechanism operable to releaseably hold the strut in the released position when the coil assembly is not energized.

Abstract: Disclosed is a load cell having a frame that includes a first and a second mounting surface. Each mounting surface is arranged on a common horizontal plane symmetrically about a central vertical axis. First and second lateral surfaces are arranged perpendicular to the first and second mounting surfaces. One or more mounting fixtures are located on the load cell at the first and second mounting surfaces and configured to attach to a support structure or a loading fixture. One or more force sensors are arranged symmetrically about the central vertical axis. One or more cavities extend the width of the frame and are arranged between a mounting fixture and the force sensors to buffer horizontal shear forces.

Abstract: Disclosed is a load cell having a frame that includes a first and a second mounting surface. Each mounting surface is arranged on a common horizontal plane symmetrically about a central vertical axis. First and second lateral surfaces are arranged perpendicular to the first and second mounting surfaces. One or more mounting fixtures are located on the load cell at the first and second mounting surfaces and configured to attach to a support structure or a loading fixture. One or more force sensors are arranged symmetrically about the central vertical axis. One or more cavities extend the width of the frame and are arranged between a mounting fixture and the force sensors.

Abstract: A clutch module which includes a first rotating member including at least one strut actuation module and a second engaged member including cam surfaces thereon for engagement by said strut actuation module. The strut actuation module includes a frame with a strut pivotally movable with respect to the frame. The strut includes an engagement end and a base end including a first side and a second side thereof. A pin or post portion extends from the frame and has an insulated bobbin with an energizable coil surrounding the bobbin. A U-shaped member including a pair of actuation legs is attached to the pin member and forms a magnetic gap between the base end of the strut and peripheral ends of the legs, such that when the coil is energized the peripheral ends of the legs are polarized in a first polarity and the frame and the strut are polarized with an opposite polarity thereby biasing the strut toward the peripheral ends and pivoting the actuation end into engagement with a cam surface of the engagement member.

Abstract: A method of identifying a product comprises forming a tagged product by adding to said product a tracer material comprising at least one tracer compound which is acceptable for use as an additive in food and subsequently analyzing a sample of said product to determine the presence of said tracer compound thereby to determine whether said sample is a sample of the tagged product. The method is especially useful for the identification of vegetable oil products from sustainably managed sources. The use of permitted food additives as tracers enables the product to be identified in the supply chain while also allowing it to be used safely in foodstuffs if required.

Abstract: A clutch module which includes a first rotating member including at least one strut actuation module and a second engaged member including cam surfaces thereon for engagement by said strut actuation module. The strut actuation module includes a frame with a strut pivotally movable with respect to the frame. The strut includes an engagement end and a base end including a first side and a second side thereof. A pin or post portion extends from the frame and has an insulated bobbin with an energizable coil surrounding the bobbin. A U-shaped member including a pair of actuation legs is attached to the pin member and forms a magnetic gap between the base end of the strut and peripheral ends of the legs, such that when the coil is energized the peripheral ends of the legs are polarized in a first polarity and the frame and the strut are polarized with an opposite polarity thereby biasing the strut toward the peripheral ends and pivoting the actuation end into engagement with a cam surface of the engagement member.

Abstract: A method of tracing an aqueous liquid, particularly an aqueous urea used for addition to a selective catalytic reduction system to remove NOx from diesel exhaust, includes adding a tracer comprising a pre-determined amount of a phenol to the liquid. The liquid can subsequently be identified by reacting a sample with a reagent containing a predetermined amount of 4-aminoantipyrine in the presence of an initiating compound such that the reaction between the reagent and a phenol in the liquid produces a chromophore and measuring the absorbance of the resulting solution of the chromophore.

Abstract: A method of tracing an aqueous liquid, particularly an aqueous urea used for addition to a selective catalytic reduction system to remove NOx from diesel exhaust includes adding a tracer comprising a pre-determined amount of a phenol to the liquid. The liquid can subsequently be identified by reacting a sample with a reagent containing a predetermined amount of 4-aminoantipyrine in the presence of an initiating compound such that the reaction between the reagent and a phenol in the liquid produces a chromophore and measuring the absorbance of the resulting solution of the chromophore.

Abstract: A clutch module which includes a first rotating member including at least one strut actuation module and a second engaged member including cam surfaces thereon for engagement by said strut actuation module. The strut actuation module includes a frame with a strut pivotally movable with respect to the frame. The strut includes an engagement end and a base end including a first side and a second side thereof. A pin or post portion extends from the frame and has an insulated bobbin with an energizable coil surrounding the bobbin. A U-shaped member including a pair of actuation legs is attached to the pin member and forms a magnetic gap between the base end of the strut and peripheral ends of the legs, such that when the coil is energized the peripheral ends of the legs are polarized in a first polarity and the frame and the strut are polarized with an opposite polarity thereby biasing the strut toward the peripheral ends and pivoting the actuation end into engagement with a cam surface of the engagement member.

Abstract: A clutch module which includes a first rotating member including at least one strut actuation module and a second engaged member including cam surfaces thereon for engagement by said strut actuation module. The strut actuation module includes a frame with a strut pivotally movable with respect to the frame. The strut includes an engagement end and a base end including a first side and a second side thereof. A pin or post portion extends from the frame and has an insulated bobbin with an energizable coil surrounding the bobbin. A U-shaped member including a pair of actuation legs is attached to the pin member and forms a magnetic gap between the base end of the strut and peripheral ends of the legs, such that when the coil is energized the peripheral ends of the legs are polarized in a first polarity and the frame and the strut are polarized with an opposite polarity thereby biasing the strut toward the peripheral ends and pivoting the actuation end into engagement with a cam surface of the engagement member.

Abstract: The invention comprises a radiation and contamination monitor for the monitoring of radiation and contamination. The instrument is intrinsically safe and comprises a radiation detector, a power source, a signal processor and a display, said power source, signal processor and display being housed within a sealed instrument housing formed from a non-metallic material which is resistant to static discharge. The detector may be housed in a detachable housing for contamination monitoring.

Abstract: A method of tracing an aqueous liquid, particularly an aqueous urea used for addition to a selective catalytic reduction system to remove NOx from diesel exhaust, includes adding a tracer comprising a pre-determined amount of a phenol to the liquid. The liquid can subsequently be identified by reacting a sample with a reagent containing a predetermined amount of 4-aminoantipyrine in the presence of an initiating compound such that the reaction between the reagent and a phenol in the liquid produces a chromophore and measuring the absorbance of the resulting solution of the chromophore.

Abstract: A method of identifying a product comprises forming a tagged product by adding to said product a tracer material comprising at least one tracer compound which is acceptable for use as an additive in food and subsequently analysing a sample of said product to determine the presence of said tracer compound thereby to determine whether said sample is a sample of the tagged product. The method is especially useful for the identification of vegetable oil products from sustainably managed sources. The use of permitted food additives as tracers enables the product to be identified in the supply chain whilst also allowing it to be used safely in foodstuffs if required.

Abstract: The invention comprises a radiation and contamination monitor for the monitoring of radiation and contamination. The instrument is intrinsically safe and comprises a radiation detector, a power source, a signal processor and a display, said power source, signal processor and display being housed within a sealed instrument housing formed from a non-metallic material which is resistant to static discharge. The detector may be housed in a detachable housing for contamination monitoring.

Abstract: A method of monitoring the flow of fluid within or from an oil or gas reservoir includes inserting a solid tracer into the reservoir. The tracer comprises at least one metal selected from caesium, niobium, tantalum, tellurium, terbium, lanthanum, gold, iridium, osmium, silver, platinum, palladium, rhenium, ruthenium, rhodium, hafnium, indium, a metal of the Lanthanide series of the periodic table, or a salt thereof. A sample of fluid within or flowing from the reservoir is collected and analysed to determine the amount of the tracer contained in the sample. A perforation tool allows for insertion of the tracer within the formation.

Abstract: A method of tracing an aqueous liquid, particularly an aqueous urea used for addition to a selective catalytic reduction system to remove NOx from diesel exhaust includes adding a tracer comprising a pre-determined amount of a phenol to the liquid. The liquid can subsequently be identified by reacting a sample with a reagent containing a predetermined amount of 4-aminoantipyrine in the presence of an initiating compound such that the reaction between the reagent and a phenol in the liquid produces a chromophore and measuring the absorbance of the resulting solution of the chromophore.

Abstract: A system for controlling a displacement drive of a motor vehicle includes a manually operable actuator movable over a fixed stroke between a first end position and a second end position. The actuator is biased to a neutral position centrally located between the first and second end positions and provides a signal representative of position of the actuator. A controller receives the signal from the actuator and produces commands for a reversible DC electric motor of the displacement drive device. The commands vary speed of the drive motor based on the position of the actuator such that the speed of the drive motor is zero at the neutral position, increases in one direction as the actuator moves toward the first end position, and increases in the other direction as the actuator moves toward the second end position.

Abstract: A powered adjustable seat assembly for a motor vehicle includes a seat, an adjuster mechanism operatively connected to the seat to adjust the seat, a controller operatively connected to the drive motor of the adjuster mechanism to selectively adjust the seat, and a plurality of lights located below the seat and operatively connected to the controller to selectively illuminate the lights upon predetermined conditions. The lights are secured to a moving portion of the adjuster mechanism so that the lights move with the seat. Preferably, one of the lights is positioned to direct illumination in a forward direction toward operator pedals, one of the lights is positioned to direct illumination in a rearward direction toward a rear seat, and one of the lights is positioned to direct light in a lateral direction toward a vehicle door.

Abstract: An electric motor including a rotational sensor is provided. Certain examples of the rotational sensor are operative to output a sinusoidal signal that corresponds to the rotational position of the motor armature in response to the potential at a single point or multiple points on the commutator. Certain other examples of the motor and rotational sensor disclosed here are operative to provide multiple pulses per rotation of the armature, which can allow for finer adjustment of devices attached to the motor. The motor and rotational sensor provides a simpler and less costly design requiring fewer parts subject to mechanical failure.