Patents by Inventor Darren B. Gruis
Darren B. Gruis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190233345Abstract: The disclosure relates to systems, compositions and methods for providing nutrients, fertilizers, crop protection agents and other crop inputs for a plant. The disclosure also relates to methods for increasing the uptake of a crop active compound into a growing plant.Type: ApplicationFiled: March 22, 2017Publication date: August 1, 2019Applicants: E. I. DU PONT DE NEMOURS AND COMPANY, PIONEER HI-BRED INTERNATIONAL, INC.Inventors: MARIOS AVGOUSTI, ROBERT RAY BURCH, TIMOTHY CASPAR, JASON DEBRUIN, JOHN D. EVERARD, RAJEEV L. GOROWARA, DARREN B. GRUIS, RAFAEL HERRMANN, SHANE FRANCIS KENDRA, KATRINA KRATZ, JACY CAMERON MACCHIA, RYAN ARTHUR PAPE, JEFFREY R. SCHUSSLER, NING WANG, JIHUA ZHANG
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Patent number: 9163233Abstract: Compositions and methods for modulating expression of gene products are provided. Compositions comprise suppression cassettes that comprise a convergent promoter pair operably linked to a silencing element that, upon expression, is capable of decreasing the expression of one or more target polynucleotides of interest. Compositions of the invention also include transformed plants, plant cells, plant tissues, and plant seeds. Methods of transformation and regeneration of plants comprising the novel constructs are provided. The methods find use in regulating gene expression, particularly genes associated with agronomic traits of interest. Further provided are promoter sequences, cells, plants, and vectors comprising these promoter sequences and methods of their use.Type: GrantFiled: February 25, 2013Date of Patent: October 20, 2015Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Darren B. Gruis, Craig Hastings
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Patent number: 8404929Abstract: Compositions and methods for modulating expression of gene products are provided. Compositions comprise suppression cassettes that comprise a convergent promoter pair operably linked to a silencing element that, upon expression, is capable of decreasing the expression of one or more target polynucleotides of interest. Compositions of the invention also include transformed plants, plant cells, plant tissues, and plant seeds. Methods of transformation and regeneration of plants comprising the novel constructs are provided. The methods find use in regulating gene expression, particularly genes associated with agronomic traits of interest. Further provided are promoter sequences, cells, plants, and vectors comprising these promoter sequences and methods of their use.Type: GrantFiled: September 29, 2009Date of Patent: March 26, 2013Assignee: Pioneer Hi-Bred International, Inc.Inventors: Darren B. Gruis, Criag Hastings
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Publication number: 20100088785Abstract: Compositions and methods for modulating expression of gene products are provided. Compositions comprise suppression cassettes that comprise a convergent promoter pair operably linked to a silencing element that, upon expression, is capable of decreasing the expression of one or more target polynucleotides of interest. Compositions of the invention also include transformed plants, plant cells, plant tissues, and plant seeds. Methods of transformation and regeneration of plants comprising the novel constructs are provided. The methods find use in regulating gene expression, particularly genes associated with agronomic traits of interest. Further provided are promoter sequences, cells, plants, and vectors comprising these promoter sequences and methods of their use.Type: ApplicationFiled: September 29, 2009Publication date: April 8, 2010Applicant: Pioneer Hi-Bred International, Inc.Inventors: Darren B. Gruis, Craig Hastings
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Patent number: 7557263Abstract: The present invention provides methods and compositions directed to the production of polypeptides in plant protein storage tissue. Methods of the invention include methods for producing polypeptides in protein storage tissues by decreasing the level of protease activity in the plant protein storage tissue. Compositions of the invention include plants that are genetically modified such that the activity of one or more proteases is reduced or eliminated, transformed seeds obtained from these genetically modified plants, and sequences encoding a novel member of the VPE cysteine protease family found in seed, ?-VPE. These methods and compositions find utility in altering the nutritional or other qualities of seed, and in producing useful proteins including pharmacological or industrial proteins.Type: GrantFiled: January 9, 2008Date of Patent: July 7, 2009Assignee: Pioneer Hi-Bred International, Inc.Inventors: Darren B. Gruis, Rudolf Jung
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Publication number: 20080124804Abstract: The present invention provides methods and compositions directed to the production of polypeptides in plant protein storage tissue. Methods of the invention include methods for producing polypeptides in protein storage tissues by decreasing the level of protease activity in the plant protein storage tissue. Compositions of the invention include plants that are genetically modified such that the activity of one or more proteases is reduced or eliminated, transformed seeds obtained from these genetically modified plants, and sequences encoding a novel member of the VPE cysteine protease family found in seed, ?-VPE. These methods and compositions find utility in altering the nutritional or other qualities of seed, and in producing useful proteins including pharmacological or industrial proteins.Type: ApplicationFiled: January 9, 2008Publication date: May 29, 2008Applicant: Pioneer Hi-Bred International, Inc.Inventors: Darren B. Gruis, Rudolf Jung
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Patent number: 7189889Abstract: Methods are provided for altering grain characteristics by introducing into plants, isolated nucleic acid molecules that can be used to produce transgenic plants characterized by altered number, type, or configuration of aleurone cells within the seed. Also provided are isolated nucleic acids that encode maize dek1 proteins, vectors capable of expressing such nucleic acid molecules, host cells containing such vectors, and polypeptides encoded by such nucleic acids.Type: GrantFiled: July 30, 2002Date of Patent: March 13, 2007Assignee: Pioneer Hi-Bred International, Inc.Inventors: Mitchell C. Tarczynski, Odd-Arne Olsen, Bo Shen, Stein E. Lid, Changjiang Li, Rudolf Jung, Darren B. Gruis, Jennifer A. Lorentzen, Evgueni Ananiev, Scott E. Nichols, Cunxi Wang
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Patent number: 6855871Abstract: The present invention provides methods and compositions directed to the production of polypeptides in plant protein storage tissue. Methods of the invention include methods for producing polypeptides in protein storage tissues by decreasing the level of protease activity in the plant protein storage tissue. Compositions of the invention include plants that are genetically modified such that the activity of one or more proteases is reduced or eliminated, transformed seeds obtained from these genetically modified plants, and sequences encoding a novel member of the VPE cysteine protease family found in seed, ?-VPE. These methods and compositions find utility in altering the nutritional or other qualities of seed, and in producing useful proteins including pharmacological or industrial proteins.Type: GrantFiled: August 21, 2001Date of Patent: February 15, 2005Assignee: Pioneer Hi-Bred International, Inc.Inventors: Darren B. Gruis, Rudolf Jung
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Publication number: 20030074689Abstract: Methods are provided for altering grain characteristics by introducing into plants, isolated nucleic acid molecules that can be used to produce transgenic plants characterized by altered number, type, or configuration of aleurone cells within the seed. Also provided are isolated nucleic acids that encode maize dek1 and superal proteins, vectors capable of expressing such nucleic acid molecules, host cells containing such vectors, and polypeptides encoded by such nucleic acids. Also provided is an isolated promoter natively associated with the maize dek1 coding region; and expression cassettes, vectors, and host cells comprising the promoter seuquence.Type: ApplicationFiled: July 30, 2002Publication date: April 17, 2003Inventors: Mitchell C. Tarczynski, Odd-Arne Olsen, Bo Shen, Stein E. Lid, Changjiang Li, Rudolf Jung, Darren B. Gruis, Jennifer A. Lorentzen, Evgueni Ananiev, Scott E. Nichols, Cunxi Wang
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Publication number: 20020108149Abstract: The present invention provides methods and compositions directed to the production of polypeptides in plant protein storage tissue. Methods of the invention include methods for producing polypeptides in protein storage tissues by decreasing the level of protease activity in the plant protein storage tissue. Compositions of the invention include plants that are genetically modified such that the activity of one or more proteases is reduced or eliminated, transformed seeds obtained from these genetically modified plants, and sequences encoding a novel member of the VPE cysteine protease family found in seed, &egr;-VPE. These methods and compositions find utility in altering the nutritional or other qualities of seed, and in producing useful proteins including pharmacological or industrial proteins.Type: ApplicationFiled: August 21, 2001Publication date: August 8, 2002Applicant: Pioneer Hi-Bred International, Inc.Inventors: Darren B. Gruis, Rudolf Jung