Patents by Inventor Darren C. Phillips

Darren C. Phillips has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SINGLE-CHAIN TRAIL-RECEPTOR AGONIST PROTEINS
    Publication number: 20250145688
    Abstract: Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
    Type: Application
    Filed: September 23, 2024
    Publication date: May 8, 2025
    Inventors: Fritz G. Buchanan, Christian Gieffers, Oliver Hill, Susan E. Lappe, Darren C. Phillips, Meinolf Thiemann
  • SINGLE-CHAIN TRAIL-RECEPTOR AGONIST PROTEINS
    Publication number: 20240174731
    Abstract: Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
    Type: Application
    Filed: July 14, 2023
    Publication date: May 30, 2024
    Inventors: Fritz G. Buchanan, Christian Gieffers, Oliver Hill, Susan E. Lappe, Darren C. Phillips, Meinholf Thiemann
  • ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES
    Publication number: 20230135723
    Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
    Type: Application
    Filed: June 8, 2022
    Publication date: May 4, 2023
    Inventors: Lorenzo Benatuil, Milan Bruncko, Andrew S. Judd, Yingchun Li, Andrew Mccluskey, Andrew C. Phillips, Darren C. Phillips, Jane Seagal, Andrew J. Souers
  • ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES
    Publication number: 20230120736
    Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
    Type: Application
    Filed: April 27, 2022
    Publication date: April 20, 2023
    Inventors: Lorenzo Benatuil, Milan Bruncko, Andrew S. Judd, Yingchun Li, Andrew Mccluskey, Andrew C. Phillips, Darren C. Phillips, Jane Seagal, Andrew J. Souers
  • Single-Chain Trail-Receptor Agonist Proteins
    Publication number: 20210040178
    Abstract: Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
    Type: Application
    Filed: August 14, 2020
    Publication date: February 11, 2021
    Inventors: Fritz G. Buchanan, Christian Gieffers, Oliver Hill, Susan E. Lappe, Darren C. Phillips, Meinholf Thiemann
  • ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES
    Publication number: 20200147235
    Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
    Type: Application
    Filed: June 8, 2017
    Publication date: May 14, 2020
    Inventors: Lorenzo Benatuil, Milan Bruncko, Andrew S. Judd, Yingchun Li, Andrew Mccluskey, Andrew C. Phillips, Darren C. Phillips, Jane Seagal, Andrew J. Souers
  • ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES
    Publication number: 20200121803
    Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
    Type: Application
    Filed: June 8, 2017
    Publication date: April 23, 2020
    Inventors: Lorenzo Benatuil, Milan Bruncko, Andrew S. Judd, Yingchun Li, Andrew Mccluskey, Andrew C. Phillips, Darren C. Phillips, Jane Seagal, Andrew J. Souers
  • ANTI-CD98 ANTIBODIES AND ANTIBODY DRUG CONJUGATES
    Publication number: 20200002432
    Abstract: The invention relates to anti-CD98 antibodies and antibody drug conjugates (ADCs), including compositions and methods of using said antibodies and ADCs.
    Type: Application
    Filed: June 8, 2017
    Publication date: January 2, 2020
    Inventors: Lorenzo Benatuil, Milan Bruncko, George Doherty, Robin R. Frey, Andrew S. Judd, Yingchun Li, Andrew Mccluskey, Andrew C. Phillips, Darren C. Phillips, Jane Seagal, Xiaohong Song, Andrew J. Souers, Gerard M. Sullivan, Zhi-Fu Tao
  • Single-Chain Trail-Receptor Agonist Proteins
    Publication number: 20180222962
    Abstract: Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
    Type: Application
    Filed: February 2, 2018
    Publication date: August 9, 2018
    Inventors: Fritz G. Buchanan, Christian Gieffers, Oliver Hill, Susan E. Lappe, Darren C. Phillips, Meinholf Thiemann
  • Single-chain trail-receptor agonist proteins
    Patent number: 9908927
    Abstract: Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
    Type: Grant
    Filed: April 23, 2015
    Date of Patent: March 6, 2018
    Assignees: AbbVie Inc., Apogenix AG
    Inventors: Oliver Hill, Christian Gieffers, Meinolf Thiemann, Fritz G. Buchanan, Darren C. Phillips, Susan E. Lappe
  • SINGLE-CHAIN TRAIL-RECEPTOR AGONIST PROTEINS
    Publication number: 20150337027
    Abstract: Provided herein are specific TRAIL receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a TRAIL-associated disease or disorder. The TRAIL receptor agonist proteins provided herein comprise three soluble TRAIL domains and an Fc fragment. The TRAIL receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
    Type: Application
    Filed: April 23, 2015
    Publication date: November 26, 2015
    Inventors: Oliver Hill, Christian Gieffers, Meinolf Thiemann, Fritz G. Buchanan, Darren C. Phillips, Susan E. Lappe