Abstract: The present invention relates to an immunogenic composition against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), especially to an immunogenic composition having a recombinant SARS-CoV-2 S protein and adjuvant.

Abstract: A lever assembly and a master cylinder are provided. The lever assembly includes a lever and an adjuster mechanism that changes the mechanical advantage of the lever. The reach of the lever relative to a handlebar can be adjusted. Both the mechanical advantage and reach of the lever can be adjusted without tools and while a vehicle including the same is operated. The master cylinder includes a reservoir in a clamp area. A reservoir bladder fits into the reservoir. A cover encloses the bladder and includes a vent opening making the bladder at atmospheric pressure such that air can move into the bladder and out of the bladder. The master cylinder can be bled without reorienting the master cylinder. A method of adjusting a mechanical advantage of a lever and a method of bleeding a braking system without reorienting the master cylinder are also provided.

Abstract: A disc brake rotor comprises an internally disposed splined surface defining a circular opening and including one or more axially disposed internal splines that are adapted to be received on external splines of a splined structure of a wheel hub, the surface including a non-continuity such as a cut-away portion of the surface into which independent splines are selectively actuable to align with the internal splines as a part of the surface to allow the rotor to be connected to or released from the hub without using any tools or the like. Preferably, the independent splines are finger actuable, and provide through a workpiece comprising a locking hammer of locking foot.

Abstract: A lever assembly and a master cylinder are provided. The lever assembly includes a lever and an adjuster mechanism that changes the mechanical advantage of the lever. The reach of the lever relative to a handlebar can be adjusted. Both the mechanical advantage and reach of the lever can be adjusted without tools and while a vehicle including the same is operated. The master cylinder includes a reservoir in a clamp area. A reservoir bladder fits into the reservoir. A cover encloses the bladder and includes a vent opening making the bladder at atmospheric pressure such that air can move into the bladder and out of the bladder. The master cylinder can be bled without reorienting the master cylinder. A method of adjusting a mechanical advantage of a lever and a method of bleeding a braking system without reorienting the master cylinder are also provided.