Patents by Inventor Darren E. Straub

Darren E. Straub has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250011375
    Abstract: The present invention provides isolated proteins isolatable from an E. coli, such as avian pathogenic E. coli. Also provided by the present invention are compositions that include one or more of the proteins, and methods for making and methods for using the proteins.
    Type: Application
    Filed: October 28, 2022
    Publication date: January 9, 2025
    Inventors: Graham J.M. Cox, Daryll Emery, Darren E. Straub, Lisa Herron-Olson, Patricia Tam, Drew M. Catron
  • Publication number: 20240285748
    Abstract: Provided herein are veterinary viral vectors and vaccines based on genetically engineered Pichinde viruses that include three or more genomic segments. The first genomic segment includes a coding region encoding a Z protein and a coding region encoding a L RdRp protein. The second genomic segment includes a coding region encoding a nucleoprotein (NP) and the third genomic segment includes a coding region encoding a glycoprotein. At least one of the second and third genomic segments further includes a donor gene sequence encoding an adenovirus capsid protein in full length or any functional fragment thereof. Further provided are methods for using a reverse genetics system, and methods for producing an immune response against adenovirus or Hemorrhagic Enteritis Virus (HEV) infection of a subject such as a turkey.
    Type: Application
    Filed: June 21, 2022
    Publication date: August 29, 2024
    Inventors: Vikram Verma, Darren E. Straub, Daryll A. Emery
  • Patent number: 10183974
    Abstract: The present invention provides isolated polypeptides isolatable from a Fusobacterium spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.
    Type: Grant
    Filed: September 8, 2016
    Date of Patent: January 22, 2019
    Assignee: EPITOPIX, LLC
    Inventors: Darren E. Straub, Daryll A. Emery
  • Patent number: 10086059
    Abstract: The present invention provides isolated metal regulated polypeptides obtainable from a Campylobacter spp., and compositions including the polypeptides. The present invention also includes methods for using the compositions disclosed herein, including methods for treating in infection in a subject, for treating a condition caused by a Campylobacter spp., and for decreasing colonization of an animal.
    Type: Grant
    Filed: November 13, 2012
    Date of Patent: October 2, 2018
    Assignee: EPITOPIX, LLC
    Inventors: Darren E. Straub, Daryll A. Emery
  • Patent number: 9981026
    Abstract: The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such E. coli or Salmonella. Examples of Salmonella strains that can be used include, for instance, S. enterica serovar Newport, S. enterica serovar Enteritidis, S. enterica serovar Typhimurium, and S. enterica serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions.
    Type: Grant
    Filed: December 6, 2016
    Date of Patent: May 29, 2018
    Assignee: EPITOPIX, LLC
    Inventors: Daryll A. Emery, Darren E. Straub, Laura Wonderling
  • Patent number: 9981028
    Abstract: The present invention provides isolated polypeptides isolatable from a Staphylococcus spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: May 29, 2018
    Assignee: EPITOPIX, LLC
    Inventors: Daryll A. Emery, Darren E. Straub, Lisa L. Herron-Olson, Laura Wonderling
  • Patent number: 9950052
    Abstract: The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such E. coli or Salmonella. Examples of Salmonella strains that can be used include, for instance, S. enterica serovar Newport, S. enterica serovar Enteritidis, S. enterica serovar Typhimurium, and S. enterica serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions.
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: April 24, 2018
    Assignee: EPITOPIX, LLC
    Inventors: Daryll A. Emery, Darren E. Straub, Laura Wonderling
  • Patent number: 9943581
    Abstract: The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such E. coli or Salmonella. Examples of Salmonella strains that can be used include, for instance, S. enterica serovar Newport, S. enterica serovar Enteritidis, S. enterica serovar Typhimurium, and S. enterica serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions.
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: April 17, 2018
    Assignee: EPITOPIX, LLC
    Inventors: Daryll A. Emery, Darren E. Straub, Laura Wonderling
  • Patent number: 9925253
    Abstract: The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such as E. coli or Salmonella. Examples of Salmonella strains that can be used include, for instance, S. enterica serovar Newport, S. enterica serovar Enteritidis, S. enterica serovar Typhimurium, and S. enterica serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: March 27, 2018
    Assignee: EPITOPIX, LLC
    Inventors: Daryll A. Emery, Darren E. Straub, Laura Wonderling
  • Patent number: 9801932
    Abstract: The present invention provides isolated polypeptides isolatable from a Yersinia spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: October 31, 2017
    Assignee: EPITOPIX, LLC
    Inventors: Daryll A. Emery, Darren E. Straub, Laura Wonderling
  • Publication number: 20170182146
    Abstract: The present invention provides isolated polypeptides isolatable from a Staphylococcus spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.
    Type: Application
    Filed: March 9, 2017
    Publication date: June 29, 2017
    Inventors: Daryll A. Emery, Darren E. Straub, Lisa L. Herron-Olson, Laura Wonderling
  • Patent number: 9623076
    Abstract: The present invention provides isolated polypeptides isolatable from a Staphylococcus spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.
    Type: Grant
    Filed: February 15, 2016
    Date of Patent: April 18, 2017
    Assignee: EPITOPIX, LLC
    Inventors: Daryll A. Emery, Darren E. Straub, Lisa L. Herron-Olson, Laura Wonderling
  • Publication number: 20170087238
    Abstract: The present invention provides compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccarhide at a concentration of no greater than about 10.0 endotoxin units per milliliter. The present invention also provides methods of making and methods of using such compositions.
    Type: Application
    Filed: September 7, 2016
    Publication date: March 30, 2017
    Inventors: Daryll A. Emery, Darren E. Straub, Donavan E. Zammert, Gayla K. Kallevig
  • Publication number: 20170080072
    Abstract: The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such E. coli or Salmonella. Examples of Salmonella strains that can be used include, for instance, S. enterica serovar Newport, S. enterica serovar Enteritidis, S. enterica serovar Typhimurium, and S. enterica serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions.
    Type: Application
    Filed: December 6, 2016
    Publication date: March 23, 2017
    Inventors: Daryll A. Emery, Darren E. Straub, Laura Wonderling
  • Publication number: 20170080074
    Abstract: The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such E. coli or Salmonella. Examples of Salmonella strains that can be used include, for instance, S. enterica serovar Newport, S. enterica serovar Enteritidis, S. enterica serovar Typhimurium, and S. enterica serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions.
    Type: Application
    Filed: December 7, 2016
    Publication date: March 23, 2017
    Inventors: Daryll A. Emery, Darren E. Straub, Laura Wonderling
  • Publication number: 20170080073
    Abstract: The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such E. coli or Salmonella. Examples of Salmonella strains that can be used include, for instance, S. enterica serovar Newport, S. enterica serovar Enteritidis, S. enterica serovar Typhimurium, and S. enterica serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions.
    Type: Application
    Filed: December 7, 2016
    Publication date: March 23, 2017
    Inventors: Daryll A. Emery, Darren E. Straub, Laura Wonderling
  • Publication number: 20170035872
    Abstract: The present invention provides compositions including polypeptides having the characteristics of polypeptides expressed by a reference microbe such E. coli or Salmonella. Examples of Salmonella strains that can be used include, for instance, S. enterica serovar Newport, S. enterica serovar Enteritidis, S. enterica serovar Typhimurium, and S. enterica serovar Dublin. Also provided are compositions including polypeptides having a particular molecular weight and a mass fingerprint that includes polypeptide fragments having a particular set of masses, or polypeptides having an amino acid sequence with at least about 95% identity with an amino acid sequence, wherein the polypeptide has seroreactive activity. The present invention also provides methods of making and methods of using such compositions.
    Type: Application
    Filed: September 29, 2016
    Publication date: February 9, 2017
    Inventors: Daryll A. Emery, Darren E. Straub, Laura Wonderling
  • Publication number: 20160376327
    Abstract: The present invention provides isolated polypeptides isolatable from a Fusobacterium spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.
    Type: Application
    Filed: September 8, 2016
    Publication date: December 29, 2016
    Inventors: Darren E. Straub, Daryll A. Emery
  • Publication number: 20160355554
    Abstract: The present invention provides isolated polypeptides isolatable from a Fusobacterium spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.
    Type: Application
    Filed: August 22, 2016
    Publication date: December 8, 2016
    Inventors: Darren E. Straub, Daryll A. Emery
  • Patent number: 9487564
    Abstract: The present invention provides isolated polypeptides isolatable from a Fusobacterium spp. Also provided by the present invention are compositions that include one or more of the polypeptides, and methods for making and methods for using the polypeptides.
    Type: Grant
    Filed: April 24, 2008
    Date of Patent: November 8, 2016
    Assignee: EPITOPIX, LLC
    Inventors: Darren E. Straub, Daryll A. Emery