Abstract: An adjustable guided rake apparatus and method, which enable an adjustable guided rake user to configure an adjustable rake guide to a specified height in relation to a secondary surface, which will then define the height of the grading edge of the grading rake head in relation to a primary surface. The adjustable guided rake user is able to move the grading rake head along a primary surface, in order to shift material along the surface, while the adjustable rake guide runs along the secondary surface, guiding the grading rake head.

Abstract: The present invention relates to a transdermal patch comprising a pharmaceutical formulation, the formulation comprising ropivacaine or an opioid, a pharmaceutically-acceptable adhesive and optionally one or more excipients selected from the group consisting of carrier oils, penetration enhancers and hydrophilic materials. The present invention also relates to methods of preparation of such a pharmaceutical formulation, as well as the use of such a transdermal patch in the treatment of pain (e.g. nociceptive and/or neuropathic pain).

Abstract: An adjustable guided rake apparatus and method, which enable an adjustable guided rake user to configure an adjustable rake guide to a specified height in relation to a secondary surface, which will then define the height of the grading edge of the grading rake head in relation to a primary surface. The adjustable guided rake user is able to move the grading rake head along a primary surface, in order to shift material along the surface, while the adjustable rake guide runs along the secondary surface, guiding the grading rake head.

Abstract: An adjustable guided rake apparatus and method, which enable an adjustable guided rake user to configure an adjustable rake guide to a specified height in relation to a secondary surface, which will then define the height of the grading edge of the grading rake head in relation to a primary surface. The adjustable guided rake user is able to move the grading rake head along a primary surface, in order to shift material along the surface, while the adjustable rake guide runs along the secondary surface, guiding the grading rake head.

Abstract: The present invention provides an adjustable guided rake apparatus and method which enables an adjustable guided rake user to configure an adjustable rake guide to a specified height in relation to a secondary surface, which will then define the height of the grading edge of the grading rake head in relation to a primary surface. The adjustable guided rake user is able to move the grading rake head along a primary surface, in order to shift material along the surface, while the adjustable rake guide runs along the secondary surface, guiding the grading rake head.

Abstract: The present invention relates to a transdermal patch comprising a pharmaceutical formulation, the formulation comprising ropivacaine or an opioid, a pharmaceutically-acceptable adhesive and optionally one or more excipients selected from the group consisting of carrier oils, penetration enhancers and hydrophilic materials. The present invention also relates to methods of preparation of such a pharmaceutical formulation, as well as the use of such a transdermal patch in the treatment of pain (e.g. nociceptive and/or neuropathic pain).

Abstract: The present invention relates to a pharmaceutical formulation suitable for nebulisation which comprises an aqueous suspension of (2S)-3-[4-({[4-(aminocarbonyl)-1-piperidinyl]carbonyl}oxy)phenyl]-2-{[2-(2-methylphenoxy)acetyl]amino}pentanoyl)amino] propanoic acid or a salt or solvate thereof. Methods and uses of the formulation in the treatment of respiratory disorders such as asthma are also described.

Abstract: The present invention relates to a pharmaceutical formulation suitable for nebulisation which comprises an aqueous solution of (2S)-3-[4-({[4-(aminocarbonyl)-1-piperidinyl]carbonyl}oxy)phenyl]-2-[((2S)-4-methyl-2-{[2-(2-methylphenoxy)acetyl]amino}pentanoyl)amino] propanoic acid or a salt or solvate thereof. Methods and uses of the formulation in the treatment of respiratory disorders such as asthma are also described.