Abstract: An actuator for an inhaler for delivering medicament by inhalation, comprising: a main body (2) comprising a tubular member (8) for receiving a canister (7) containing medicament and having a valve stem (11) extending therefrom; and an outlet assembly (4), as a part formed separately of the main body (2), comprising a mouthpiece for guiding medicament to the mouth of a user and a nozzle block (20) for receiving the valve stem (11) of the canister (7) and delivering medicament from the canister (7) into the mouthpiece; wherein at least a part of at least one of the main body (2) and the outlet assembly (4) is configured so as to deform or break on separating the outlet assembly (4) from the main body (2) so as to prevent re-use of the actuator; characterized in that the main body (2) and the outlet assembly (4) are composed of materials having different constitution.

Abstract: An actuator for an inhaler for administering medicament by inhalation, comprising: a main body (102) comprising an elongate tubular member (108) for receiving a canister (107) containing medicament and having a valve stem (111) extending therefrom, the tubular member (108) including a lateral opening (114) at one end thereof; and an outlet assembly (104) comprising a mouthpiece for guiding medicament to the mouth of a user and a nozzle block (120) for receiving the valve stem (111) of the canister (107) and delivering medicament from the canister (107) into the mouthpiece, the outlet assembly (104) being detachably mounted, through the lateral opening (114), to the main body (102) at an angle transverse to the length of the tubular member (108); characterized in that one of the main body (102) and the outlet assembly (104) further comprises at least one resiliently biased member, which is configured to engage with at least one part of the other of the main body (102) and the outlet assembly (104) and thereby