Patents by Inventor Darren LIMB

Darren LIMB has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHESIS OF BICYCLE TOXIN CONJUGATES, AND INTERMEDIATES THEREOF
    Publication number: 20260265299
    Abstract: The present invention relates methods of preparing Bicycle toxin conjugates, and intermediates thereof.
    Type: Application
    Filed: March 8, 2024
    Publication date: September 10, 2026
    Applicant: BicycleTx Limited
    Inventors: Darren Limb, William Moss, David Witty, Jie Zhang, Jinguang Lin, William Nesbit
  • SYNTHESIS OF BICYCLE TOXIN CONJUGATES, AND INTERMEDIATES THEREOF
    Publication number: 20240400608
    Abstract: The present invention relates to Bicycle toxin conjugates, methods for preparation, and methods of use for treating cancer.
    Type: Application
    Filed: September 2, 2022
    Publication date: December 5, 2024
    Applicant: BricycleTx Limited
    Inventors: David Witty, Darren Limb, Byoung Joon Min, Liwen He, William J. Sanders, Ernest Obinna Nnanabu
  • BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 AND USES THEREOF
    Publication number: 20230181749
    Abstract: The present invention relates to a Bicycle toxin conjugate BT8009, or pharmaceutically acceptable salts thereof, or pharmaceutical compositions thereof, and uses thereof. In one embodiment, the pharmaceutical composition comprises BT8009, histidine, sucrose and Polysorbate 20. In another embodiment, the pharmaceutical composition is for use in treating an advanced solid tumor malignancy associated with Nectin-4-expression in a patient, preferably in combination with Nivolumab.
    Type: Application
    Filed: May 20, 2021
    Publication date: June 15, 2023
    Inventors: Amy Katherine DICKSON, Darren LIMB, Lisa MAHNKE, Michael RIGBY, Terrence Allen WEST, David WITTY