Patents by Inventor Darren M. Platt

Darren M. Platt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYSTEMS AND METHODS FOR ENGINEERING NUCLEIC ACID CONSTRUCTS USING SCORING TECHNIQUES
    Publication number: 20140038294
    Abstract: Systems and methods are provided for defining a nucleic acid construct for integration at locus L of an organism. Nucleic acid requests are received, each such request specifying a genetic change to L. The request are expanded into component polynucleotides which are then arranged into {AR1, . . . , ARm} different arrangements, each ARi in {AR1, . . . , ARm} defining a different arrangement of the component polynucleotides. A score Si for each ARi in {AR1, . . . , ARm} is determined based on whether source constructs encoding a portion of ARi are physically present. An ARf in {AR1, . . . , ARm} is selected based on the score for ARf. Primer pairs are calculated to amplify the portions of ARf not represented in the source constructs. The portions of ARf amplified by the primer pairs and the portions of ARf in the source constructs, ordered by ARf, define the nucleic acid construct.
    Type: Application
    Filed: October 11, 2012
    Publication date: February 6, 2014
    Applicant: Amyris Biotechnologies, Inc.
    Inventors: Darren M. Platt, Michael W. Bissell, Sunil S. Chandran, Brian L. Hawthorne, Erik Jedediah Dean, Christopher Dolan
  • Systems and methods for engineering nucleic acid constructs using scoring techniques
    Patent number: 8332160
    Abstract: Systems and methods are provided for defining a nucleic acid construct for integration at locus L of an organism. Nucleic acid requests are received, each such request specifying a genetic change to L. The request are expanded into component polynucleotides which are then arranged into {AR1, . . . , ARm} different arrangements, each ARi in {AR1, . . . , ARm} defining a different arrangement of the component polynucleotides. A score Si for each ARi in {AR1, . . . , ARm} is determined based on whether source constructs encoding a portion ofARi are physically present. An ARf in {AR1, . . . , ARm} is selected based on the score for ARf. Primer pairs are calculated to amplify the portions of ARf not represented in the source constructs. The portions of ARf amplified by the primer pairs and the portions of ARf in the source constructs, ordered by ARf, define the nucleic acid construct.
    Type: Grant
    Filed: April 9, 2012
    Date of Patent: December 11, 2012
    Assignee: Amyris Biotechnologies, Inc.
    Inventors: Darren M. Platt, Michael W. Bissell, Sunil S. Chandran, Brian L. Hawthorne, Erik Jedediah Dean, Christopher Dolan
  • GENETICALLY MODIFIED MICROBES PRODUCING ISOPRENOIDS
    Publication number: 20100311065
    Abstract: Provided herein are methods of generating genetically modified yeast cells, e.g., genetically modified diploid and haploid yeast cells, that comprise novel polypeptides, and genetically modified yeast cells that persistently produce isoprenoid compounds in industrial fermentation processes, produced thereby.
    Type: Application
    Filed: June 1, 2010
    Publication date: December 9, 2010
    Inventors: Jeffrey A. Ubersax, Darren M. Platt