Patents by Inventor Darren P. Baker

Darren P. Baker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYALKYLENE POLYMER COMPOUNDS AND USES THEREOF
    Publication number: 20170049904
    Abstract: The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as chronic hepatitis C.
    Type: Application
    Filed: August 15, 2016
    Publication date: February 23, 2017
    Applicant: BIOGEN MA INC.
    Inventors: KoChung LIN, Blake PEPINSKY, Ling Ling CHEN, Donna M. HESS, Edward Y. LIN, Russell C. PETTER, Darren P. BAKER
  • TREATMENT OF MELANOMA WITH INTERFERON-BETA AND RAS-RAF-MEK-ERK INHIBITOR COMBINATION THERAPY
    Publication number: 20160228513
    Abstract: This description relates to the use of a polymer-conjugated interferon-beta as monotherapy or in combination with other cancer therapies.
    Type: Application
    Filed: October 15, 2015
    Publication date: August 11, 2016
    Applicant: BIOGEN MA INC.
    Inventors: Darren P. BAKER, Ingrid B.J.K. JOSEPH, Xinzhong WANG
  • Polyalkylene Polymer Compounds and Uses Thereof
    Publication number: 20150246097
    Abstract: The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as chronic hepatitis C.
    Type: Application
    Filed: August 30, 2013
    Publication date: September 3, 2015
    Applicant: Biogen Idec MA Inc.
    Inventors: KoChung Lin, Blake Pepinsky, Ling Ling Chen, Donna M. Hess, Edward Y. Lin, Russell C. Petter, Darren P. Baker
  • Polyalkylene Polymer Compounds and Uses Thereof
    Publication number: 20150132259
    Abstract: The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as chronic hepatitis C.
    Type: Application
    Filed: August 30, 2013
    Publication date: May 14, 2015
    Applicant: Biogen Idec MA Inc.
    Inventors: KoChung Lin, Blake Pepinsky, Ling Ling Chen, Donna M. Hess, Edward Y. Lin, Russell C. Petter, Darren P. Baker
  • Polyalkylene polymer compounds and uses thereof
    Patent number: 8524660
    Abstract: The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as chronic hepatitis C.
    Type: Grant
    Filed: September 12, 2011
    Date of Patent: September 3, 2013
    Assignee: Biogen Idec MA Inc.
    Inventors: KoChung Lin, R. Blake Pepinsky, Ling Ling Chen, Donna M. Hess, Edward Y. Lin, Russell C. Petter, Darren P. Baker
  • INTERFERON-BETA FOR USE AS MONOTHERAPY OR IN COMBINATION WITH OTHER CANCER THERAPIES
    Publication number: 20120082647
    Abstract: This description relates to the use of a polymer-conjugated interferon-beta as monotherapy or in combination with other cancer therapies.
    Type: Application
    Filed: September 28, 2011
    Publication date: April 5, 2012
    Inventors: Darren P. Baker, Ingrid B. J. K. Joseph, Xinzhong Wang
  • POLYALKYLENE POLYMER COMPOUNDS AND USES THEREOF
    Publication number: 20120014916
    Abstract: The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as chronic hepatitis C.
    Type: Application
    Filed: September 12, 2011
    Publication date: January 19, 2012
    Inventors: KoChung Lin, R. Blake Pepinsky, Ling Ling Chen, Donna M. Hess, Edward Y. Lin, Russell C. Petter, Darren P. Baker
  • Polyalkylene polymer compounds and uses thereof
    Patent number: 8017733
    Abstract: The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as chronic hepatitis C.
    Type: Grant
    Filed: July 16, 2004
    Date of Patent: September 13, 2011
    Assignee: Biogen Idec MA Inc.
    Inventors: KoChung Lin, R. Blake Pepinsky, Ling Ling Chen, Donna M. Hess, Edward Y. Lin, Russell C. Petter, Darren P. Baker
  • Antibodies to Phosphorylated IRAK4
    Publication number: 20100279316
    Abstract: The present invention relates to antibodies that bind phosphorylated forms of IRAK4, methods of using such antibodies to detect IRAK4 biological activity, and methods for the detection, diagnosis, and prognostication of pathological conditions related to IRAK4 biological activity. ERAK4 is one member of a small family of highly conserved cytoplasmic signal transduction proteins characterized by the presence of an N-terminal “death domain” and a C-terminal serine-threonine kinase domain. IRAK4 functions in cytoplasmic signal transduction pathways by interacting with membrane spanning proteins which play, inter alia, critical roles in vertebrate immune system function.
    Type: Application
    Filed: January 9, 2008
    Publication date: November 4, 2010
    Inventors: Leonid Gorelik, Darren P. Baker, Catherine A. Hession, Karyn Van De Mark, Robert M. Arduini, Craig Wildes
  • Hydrophobically-modified protein compositions and methods
    Publication number: 20090054632
    Abstract: Hydrophobically-modified proteins and methods of making them are described. A hydrophobic moiety is attached to a surface amino acid residue of the protein. The hydrophobic moiety can be a lipid or a peptide. Alternatively, the protein can be derivatized by a wide variety of chemical reactions that append a hydrophobic structure to the protein. The preferred protein is of mammalian origin and is selected from the group consisting of Sonic, Indian, and Desert hedgehog. The hydrophobic moiety is used as a convenient tether to which may be attached a vesicle such as a cell membrane, liposome, or micelle.
    Type: Application
    Filed: August 20, 2007
    Publication date: February 26, 2009
    Applicants: Biogen Idec MA Inc., Curis, Inc.
    Inventors: R. Blake Pepinsky, Alphonse Galdes, Ellen A. Garber, Darren P. Baker, Jeffery A. Porter, Frederick R. Taylor, Kevin P. Williams, Russell C. Petter, Kathryn Strauch, Paul H. Weinreb, Dingyi Wen, Chenhui Zeng
  • Hydrophobically-modified protein compositions and methods
    Patent number: 6897297
    Abstract: Hydrophobically-modified proteins and methods of making them are described. A hydrophobic moiety is attached to a surface amino acid residue of the protein. The hydrophobic moiety can be a lipid or a peptide. Alternatively, the protein can be derivatized by a wide variety of chemical reactions that append a hydrophobic structure to the protein. The preferred protein is of mammalian origin and is selected from the group consisting of Sonic, Indian, and Desert hedgehog. The hydrophobic moiety is used as a convenient tether to which may be attached a vesicle such as a cell membrane, liposome, or micelle.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: May 24, 2005
    Assignees: Curis, Inc., Biogen Idec Inc.
    Inventors: R. Blake Pepinsky, Chenhui Zeng, Darren P. Baker, Dingyi Wen, Kevin P. Williams, Ellen A. Garber, Kathryn L. Strauch, Frederick R. Taylor, Paul H. Weinreb, Russell C. Petter, Alphonse Galdes, Jeffrey Porter
  • Hydrophobically-modified hedgehog protein compositions and methods
    Patent number: 6444793
    Abstract: Hydrophobically-modified proteins and methods of making them are described. A hydrophobic moiety is attached to a surface amino acid residue of the protein. The hydrophobic moiety can be a lipid or a peptide. Alternatively, the protein can be derivatized by a wide variety of chemical reactions that append a hydrophobic structure to the protein. The preferred protein is of mammalian origin and is selected from the group consisting of Sonic, Indian, and Desert hedgehog. The hydrophobic moiety is used as a convenient tether to which may be attached a vesicle such as a cell membrane, liposome, or micelle.
    Type: Grant
    Filed: June 3, 1999
    Date of Patent: September 3, 2002
    Assignees: Curis, Inc., Biogen, Inc.
    Inventors: R. Blake Pepinsky, Darren P. Baker, Dingyi Wen, Kevin P. Williams, Ellen A. Garber, Frederick R. Taylor, Alphonse Galdes, Jeffrey Porter