Patents by Inventor Darren R. Carpizo

Darren R. Carpizo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compounds and therapeutic methods
    Patent number: 12344626
    Abstract: The invention provides a complex comprising Zn2+ and a compound of formula (I): or a deuterated analog thereof, or an ion or poly-ion thereof, or a salt thereof that is useful for treating cancer, as well as compositions and kits comprising such complexes.
    Type: Grant
    Filed: April 22, 2020
    Date of Patent: July 1, 2025
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Spencer David Kimball, Darren R. Carpizo, John A. Gilleran
  • Pharmaceutical compounds and therapeutic methods
    Patent number: 12280065
    Abstract: The invention provides a complex comprising Zn2+ and a compound of formula (I): or a deuterated analog thereof, or an ion or poly-ion thereof, or a salt thereof that is useful for treating cancer, as well as compositions and kits comprising such complexes.
    Type: Grant
    Filed: April 22, 2020
    Date of Patent: April 22, 2025
    Assignee: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Spencer David Kimball, Darren R. Carpizo, John A. Gilleran
  • PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS
    Publication number: 20220185827
    Abstract: The invention provides a complex comprising Zn2+ and a compound of formula (I): or a deuterated analog thereof, or an ion or poly-ion thereof, or a salt thereof that is useful for treating cancer, as well as compositions and kits comprising such complexes.
    Type: Application
    Filed: April 22, 2020
    Publication date: June 16, 2022
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Spencer David KIMBALL, Darren R. CARPIZO, John A. GILLERAN
  • PHARMACEUTICAL COMPOUNDS AND THERAPEUTIC METHODS
    Publication number: 20220096492
    Abstract: The invention provides a complex comprising Zn2+ and a compound of formula (I): or a deuterated analog thereof, or an ion or poly-ion thereof, or a salt thereof that is useful for treating cancer, as well as compositions and kits comprising such complexes.
    Type: Application
    Filed: April 22, 2020
    Publication date: March 31, 2022
    Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY
    Inventors: Spencer David KIMBALL, Darren R. CARPIZO, John A. GILLERAN
  • Hydrazone derivatives for the treatment of cancer
    Patent number: 10828288
    Abstract: The invention provides compounds of formula (I): and salts thereof wherein ring A, R2, HET, X, n, and R3 have any of the meanings described in the specification, as well as compositions comprising such compounds and salts, and methods for treating cancer using such compounds and salts.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: November 10, 2020
    Assignees: Rutgers, the State University of New Jersey, The Research Foundation for the State University of New York
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • Zinc complexes of hydrazones and (thio)semicarbazones and their use for the treatment of cancer
    Patent number: 10729671
    Abstract: The invention provides complexes of Zn2+ of formulae (la) and (IIa) that are useful for treating cancer, as well as compositions and kits comprising such complexes.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: August 4, 2020
    Assignees: Rutgers, the State University of New Jersey, The Research Foundation for the State University of New York
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • (Thio, oxo and seleno) semicarbazone complexes with zinc and their use for treating cancer
    Patent number: 10604481
    Abstract: The invention provides organic complexes of Zn2+ that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful for the preparation of such complexes.
    Type: Grant
    Filed: January 21, 2019
    Date of Patent: March 31, 2020
    Assignees: Rutgers, The State University of New Jersey, The Research Foundation for the State University of New York
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • (Thio, oxo, and seleno) semicarbazone derivatives and their use for treating cancer
    Patent number: 10604480
    Abstract: The invention provides compounds of formula I and II and salts thereof, wherein R1, R2, Y, R3, and R4 have any of the meanings described in the specification, as well as compositions comprising such compounds and salts, and methods for treating cancer using such compounds and salts.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: March 31, 2020
    Assignees: Rutgers, The State University of New Jersey, The Research Foundation for the State University of New York
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • (THIO, OXO AND SELENO) SEMICARBAZONE COMPLEXES WITH ZINC AND THEIR USE FOR TREATING CANCER
    Publication number: 20190256460
    Abstract: The invention provides organic complexes of Zn2+ that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful for the preparation of such complexes.
    Type: Application
    Filed: January 21, 2019
    Publication date: August 22, 2019
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • (Thio, oxo, and seleno) semicarbazone complexes with zinc and their use for treating cancer
    Patent number: 10221133
    Abstract: The invention provides organic complexes of Zn2+ of formula (I) that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful for the preparation of such complexes.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: March 5, 2019
    Assignees: Rutgers, The State University of New Jersey, The Research Foundation for the State University of New York
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • HYDRAZONE DERIVATIVES FOR THE TREATMENT OF CANCER
    Publication number: 20180000806
    Abstract: The invention provides compounds of formula (I): and salts thereof wherein ring A, R2, HET, X, n, and R3 have any of the meanings described in the specification, as well as compositions comprising such compounds and salts, and methods for treating cancer using such compounds and salts.
    Type: Application
    Filed: January 27, 2016
    Publication date: January 4, 2018
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • (THIO, OXO, AND SELENO) SEMICARBAZONE DERIVATIVES AND THEIR USE FOR TREATING CANCER
    Publication number: 20180002280
    Abstract: The invention provides compounds of formula I and II and salts thereof, wherein R1, R2, Y, R3, and R4 have any of the meanings described in the specification, as well as compositions comprising such compounds and salts, and methods for treating cancer using such compounds and salts.
    Type: Application
    Filed: January 27, 2016
    Publication date: January 4, 2018
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • (THIO, OXO, AND SELENO) SEMICARBAZONE COMPLEXES WITH ZINC AND THEIR USE FOR TREATING CANCER
    Publication number: 20180002279
    Abstract: The invention provides organic complexes of Zn2+ of formula (I) that are useful for treating cancer, as well as compositions and kits comprising such complexes, and intermediate monomer compounds that are useful for the preparation of such complexes.
    Type: Application
    Filed: January 27, 2016
    Publication date: January 4, 2018
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu
  • ZINC COMPLEXES OF HYDRAZONES AND (THIO)SEMICARBAZONES AND THEIR USE FOR THE TREATMENT OF CANCER
    Publication number: 20180000772
    Abstract: The invention provides complexes of Zn2+ of formulae (la) and (IIa) that are useful for treating cancer, as well as compositions and kits comprising such complexes.
    Type: Application
    Filed: January 27, 2016
    Publication date: January 4, 2018
    Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY O F NEW YORK
    Inventors: David J. Augeri, Anthony F. Bencivenga, Adam Blanden, Darren R. Carpizo, John A. Gilleran, Spencer David Kimball, Stewart N. Loh, Xin Yu