Patents by Inventor Darren R. Sherman

Darren R. Sherman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250058092
    Abstract: Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for stent deployment, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.
    Type: Application
    Filed: November 1, 2024
    Publication date: February 20, 2025
    Applicant: Caliber Therapeutics, LLC
    Inventors: William R. Baumbach, Darren R. Sherman, Robert S. Burgermeister
  • Patent number: 12144945
    Abstract: Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for stent deployment, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.
    Type: Grant
    Filed: February 15, 2023
    Date of Patent: November 19, 2024
    Assignee: Caliber Therapeutics, LLC
    Inventors: William R. Baumbach, Darren R. Sherman, Robert S. Burgermeister
  • Patent number: 11832803
    Abstract: A specimen retrieval system for easier tissue removal during endoscopic surgery. The device includes a specimen tube with a main tube, and a mechanism for pulling and everting the distal end of the tube into the tube, or a side channel provided within the tube. The mechanism may include a tether fixed to the distal edge of the tube, or a grasper operable to grasp the distal edge of the tube.
    Type: Grant
    Filed: November 10, 2020
    Date of Patent: December 5, 2023
    Assignee: Freehold Surgical, LLC
    Inventors: Darren R. Sherman, Jeffrey Smith
  • Patent number: 11786249
    Abstract: An apparatus and its method of use in delivering surgical tissue connectors into an area of the body and removing the surgical tissue connectors from the body area. The tissue connectors are connected to a base which allows for easy adjustment of the tissue connectors along a cord. The base includes a locking mechanism which impinges a sliding knot in the cord, and, in alternate configurations of the locking mechanism and knot, impinges on the sliding knot to prevent sliding in a loosening direction but allow sliding in a tightening direction, or allows sliding in a loosening direction.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: October 17, 2023
    Assignee: Freehold Surgical, LLC
    Inventors: Jeffrey Smith, Darren R. Sherman
  • Publication number: 20230191090
    Abstract: Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for stent deployment, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.
    Type: Application
    Filed: February 15, 2023
    Publication date: June 22, 2023
    Applicant: Caliber Therapeutics, LLC
    Inventors: William R. Baumbach, Darren R. Sherman, Robert S. Burgermeister
  • Publication number: 20210386979
    Abstract: A balloon catheter system for infusion of micelles at high pressure. The system includes a catheter with a drug eluting balloon with a perforated wall with numerous pores, a reservoir of nanoparticles in an aqueous solution disposed within the balloon or in fluid communication with the balloon. The particles may comprise drug loaded micelles, where the micelles are provided in the size range of 40 to 250 nm generally (0.040 ?m to 0.250 ?m), and the pores of the balloon wall are configured to allow passage of the micelles with a minimum of disruption, The pores are conical, with the diameter of the pore at the inside of the balloon wall smaller than the diameter of the pores at the outside of the balloon wall.
    Type: Application
    Filed: September 26, 2019
    Publication date: December 16, 2021
    Applicant: Caliber Therapeutics, LLC
    Inventors: William R. BAUMBACH, Darren R. SHERMAN
  • Publication number: 20210052262
    Abstract: A specimen retrieval system for easier tissue removal during endoscopic surgery. The device includes a specimen tube with a main tube, and a mechanism for pulling and everting the distal end of the tube into the tube, or a side channel provided within the tube. The mechanism may include a tether fixed to the distal edge of the tube, or a grasper operable to grasp the distal edge of the tube.
    Type: Application
    Filed: November 10, 2020
    Publication date: February 25, 2021
    Applicant: Freehold Surgical, LLC
    Inventors: Darren R. Sherman, Jeffrey Smith
  • Publication number: 20210046292
    Abstract: Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.
    Type: Application
    Filed: October 20, 2020
    Publication date: February 18, 2021
    Applicant: Caliber Therapeutics, LLC
    Inventors: William R. Baumbach, Darren R. Sherman, Robert S. Burgermeister
  • Publication number: 20200375599
    Abstract: An apparatus and its method of use in delivering surgical tissue connectors into an area of the body and removing the surgical tissue connectors from the body area. The tissue connectors are connected to a base which allows for easy adjustment of the tissue connectors along a cord. The base includes a locking mechanism which impinges a sliding knot in the cord, and, in alternate configurations of the locking mechanism and knot, impinges on the sliding knot to prevent sliding in a loosening direction but allow sliding in a tightening direction, or allows sliding in a loosening direction.
    Type: Application
    Filed: August 18, 2020
    Publication date: December 3, 2020
    Applicant: Freehold Surgical, LLC
    Inventors: Jeffrey Smith, Darren R. Sherman
  • Patent number: 10835219
    Abstract: A specimen retrieval system for easier tissue removal during endoscopic surgery. The devices include a specimen tube with a main tube, and a mechanism for pulling and everting the distal end of the tube into the tube, or a side channel provided within the tube. The mechanism may include a tether fixed to the distal edge of the tube, or a grasper operable to grasp the distal edge of the tube.
    Type: Grant
    Filed: April 19, 2017
    Date of Patent: November 17, 2020
    Assignee: Freehold Surgical, LLC
    Inventors: Darren R. Sherman, Jeffrey Smith
  • Patent number: 10806909
    Abstract: Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: October 20, 2020
    Assignee: Caliber Therapeutics, LLC
    Inventors: William R. Baumbach, Darren R. Sherman, Robert S. Burgermeister
  • Patent number: 10743878
    Abstract: An apparatus and its method of use in delivering surgical tissue connectors into an area of the body and removing the surgical tissue connectors from the body area. The tissue connectors are connected to a base which allows for easy adjustment of the tissue connectors along a cord. The base includes a locking mechanism which impinges a sliding knot in the cord, and, in alternate configurations of the locking mechanism and knot, impinges on the sliding knot to prevent sliding in a loosening direction but allow sliding in a tightening direction, or allows sliding in a loosening direction.
    Type: Grant
    Filed: January 2, 2018
    Date of Patent: August 18, 2020
    Assignee: Freehold Surgical, LLC
    Inventors: Jeffrey Smith, Darren R. Sherman
  • Patent number: 10617599
    Abstract: A method of processing a raw acceleration signal, measured by an accelerometer-based compression monitor, to produce an accurate and precise estimated actual depth of chest compressions. The raw acceleration signal is filtered during integration and then a moving average of past starting points estimates the actual current starting point. An estimated actual peak of the compression is then determined in a similar fashion. The estimated actual starting point is subtracted from the estimated actual peak to calculate the estimated actual depth of chest compressions. In addition, one or more reference sensors (such as an ECG noise sensor) may be used to help establish the starting points of compressions. The reference sensors may be used, either alone or in combination with other signal processing techniques, to enhance the accuracy and precision of the estimated actual depth of compressions.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: April 14, 2020
    Assignee: ZOLL Medical Corporation
    Inventors: James A Palazzolo, Darren R Sherman, Ronald D Berger, Henry R Halperin
  • Publication number: 20190117241
    Abstract: A specimen retrieval system for easier tissue removal during endoscopic surgery. The devices include a specimen tube with a main tube, and a mechanism for pulling and everting the distal end of the tube into the tube, or a side channel provided within the tube. The mechanism may include a tether fixed to the distal edge of the tube, or a grasper operable to grasp the distal edge of the tube.
    Type: Application
    Filed: April 19, 2017
    Publication date: April 25, 2019
    Applicant: Freehold Surgical, Inc.
    Inventors: Darren R. SHERMAN, Jeffrey SMITH
  • Patent number: 10207084
    Abstract: Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.
    Type: Grant
    Filed: May 12, 2017
    Date of Patent: February 19, 2019
    Assignee: Caliber Therapeutics, Inc.
    Inventors: William R. Baumbach, Darren R. Sherman, Robert S. Burgermeister
  • Publication number: 20180361124
    Abstract: Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.
    Type: Application
    Filed: August 28, 2018
    Publication date: December 20, 2018
    Applicant: Caliber Therapeutics, Inc.
    Inventors: William R. Baumbach, Darren R. Sherman, Robert S. Burgermeister
  • Publication number: 20180116666
    Abstract: An apparatus and its method of use in delivering surgical tissue connectors into an area of the body and removing the surgical tissue connectors from the body area. The tissue connectors are connected to a base which allows for easy adjustment of the tissue connectors along a cord. The base includes a locking mechanism which impinges a sliding knot in the cord, and, in alternate configurations of the locking mechanism and knot, impinges on the sliding knot to prevent sliding in a loosening direction but allow sliding in a tightening direction, or allows sliding in a loosening direction.
    Type: Application
    Filed: January 2, 2018
    Publication date: May 3, 2018
    Applicant: Freehold Surgical, Inc.
    Inventors: Jeffrey Smith, Darren R. Sherman
  • Patent number: 9855044
    Abstract: The present invention is directed to an apparatus and its method of use in delivering surgical tissue connectors into an area of the body and removing the surgical tissue connectors from the body area. Svlore specifically, the present invention is directed to a surgical tissue connector apparatus having at least two tissue connectors connected by a length of cord and a delivery and removal tube. At least one of the tissue connectors has a base with a tapered, beveled or chamfered surface projecting from one end of the base. A hook or other type of tissue connector projects from the opposite side of the base. The hook is positioned on the base where a peripheral side surface of the base shields the hook from unintentionally snagging objects. The base peripheral surface is also dimensioned to slide easily through an interior bore of the tube. This enables the base and the projecting hook to be easily delivered through the tube into an area of the body.
    Type: Grant
    Filed: June 26, 2013
    Date of Patent: January 2, 2018
    Assignee: Freehold Surgical, Inc.
    Inventors: Jeffrey Smith, Darren R. Sherman
  • Patent number: 9795532
    Abstract: Improved automatic chest compression systems which use constricting belts, repeatedly inflating bladders, or reciprocating pistons to compress the chest. A bladder is placed between the chest and the particular mechanism used to compress the chest during CPR. The bladder maximizes the effectiveness of chest compressions.
    Type: Grant
    Filed: February 23, 2010
    Date of Patent: October 24, 2017
    Assignee: Zoll Circulation, Inc.
    Inventors: Gregory W. Hall, James O. Jensen, Paul Escudero, Darren R. Sherman, Bob Katz
  • Publication number: 20170246432
    Abstract: Devices and methods for balloon delivery of rapamycin and other hydrophobic compounds to the wall of blood vessels. Balloon catheters, such as those used for balloon angioplasty, are modified with the addition of a reservoir of dry micelles. The micelle preparation is reconstituted and the micelles are mobilized when the aqueous solution used to inflate the balloons is injected into the catheter. The micelles are infused into tissue surrounding the balloon when pressurized fluid within the balloon leaks through the wall of the balloon.
    Type: Application
    Filed: May 12, 2017
    Publication date: August 31, 2017
    Applicant: Caliber Therapeutics, Inc.
    Inventors: William R. Baumbach, Darren R. Sherman, Robert S. Burgermeister