Patents by Inventor Darryl Bornhop

Darryl Bornhop has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for backscattering interferometry
    Patent number: 11078489
    Abstract: The present invention relates to methods and compositions for enhancing backscattering interferometry (BSI) in detection of biomolecular interactions, particularly to methods and compositions for enhancing BSI utilizing label-free aptamers, and more particularly to methods and compositions for enhancing BSI utilizing high conformational change aptamers, which may change in conformation when the aptamers bind to their target molecules.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: August 3, 2021
    Assignee: Base Pair Biotechnologies, Inc.
    Inventors: George W. Jackson, Darryl Bornhop
  • METHODS AND COMPOSITIONS FOR BACKSCATTERING INTERFEROMETRY
    Publication number: 20190119681
    Abstract: The present invention relates to methods and compositions for enhancing backscattering interferometry (BSI) in detection of biomolecular interactions, particularly to methods and compositions for enhancing BSI utilizing label-free aptamers, and more particularly to methods and compositions for enhancing BSI utilizing high conformational change aptamers, which may change in conformation when the aptamers bind to their target molecules.
    Type: Application
    Filed: April 23, 2018
    Publication date: April 25, 2019
    Inventors: George W. Jackson, Darryl Bornhop
  • Methods and compositions for backscattering interferometry
    Patent number: 9963706
    Abstract: The present invention relates to methods and compositions for enhancing backscattering interferometry (BSI) in detection of biomolecular interactions, particularly to methods and compositions for enhancing BSI utilizing label-free aptamers, and more particularly to methods and compositions for enhancing BSI utilizing high conformational change aptamers, which may change in conformation when the aptamers bind to their target molecules.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: May 8, 2018
    Assignee: Base Pair Biotechnologies, Inc.
    Inventors: George W Jackson, Darryl Bornhop
  • Methods and compositions for backscattering interferometry
    Publication number: 20160264970
    Abstract: The present invention relates to methods and compositions for enhancing backscattering interferometry (BSI) in detection of biomolecular interactions, particularly to methods and compositions for enhancing BSI utilizing label-free aptamers, and more particularly to methods and compositions for enhancing BSI utilizing high conformational change aptamers, which may change in conformation when the aptamers bind to their target molecules.
    Type: Application
    Filed: March 9, 2016
    Publication date: September 15, 2016
    Inventors: George W. Jackson, Darryl Bornhop
  • AGENTS FOR THERAPY EFFICACY MONITORING AND DEEP TISSUE IMAGING
    Publication number: 20080031823
    Abstract: Compounds and methods related to NIR molecular imaging, in-vitro and in-vivo functional imaging, therapy/efficacy monitoring, and cancer and metastatic activity imaging. Compounds and methods demonstrated pertain to the field of peripheral benzodiazepine receptor imaging, metabolic imaging, cellular respiration imaging, cellular proliferation imaging as targeted agents that incorporate signaling agents.
    Type: Application
    Filed: July 13, 2007
    Publication date: February 7, 2008
    Inventors: Darryl Bornhop, H. Manning, Mingfeng Bai, Shelby Wyatt
  • Targeted, NIR imaging agents for therapy efficacy monitoring, deep tissue disease demarcation and deep tissue imaging
    Publication number: 20060147379
    Abstract: Compounds and methods related to NIR molecular imaging, in-vitro and in-vivo functional imaging, therapy/efficacy monitoring, and cancer and metastatic activity imaging. Compounds and methods demonstrated pertain to the field of peripheral benzodiazepine receptor imaging, metabolic imaging, cellular respiration imaging, cellular proliferation imaging as targeted agents that incorporate signaling agents.
    Type: Application
    Filed: June 10, 2005
    Publication date: July 6, 2006
    Inventors: Darryl Bornhop, H. Manning, Mingfeng Bai, Shelby Wyatt
  • Refractive index determination by micro interferometric reflection detection
    Publication number: 20060012800
    Abstract: A method and an apparatus for absolute refractive index measurements are disclosed, wherein a beam of spatially coherent laser light is directed perpendicularly on to a side of a capillary tube (12) and back reflected light is detected (16) over a range of angles (22) with respect to the incident light beam. The refractive index of a liquid contained in the capillary is determined from the angle at which a marked change in the intensity of the interference fringes of the interference pattern formed by said back reflected light is observed or from the amplitude of a low frequency component of the angular variation of the intensity of interference fringes.
    Type: Application
    Filed: March 3, 2005
    Publication date: January 19, 2006
    Inventors: Darryl Bornhop, Peter Andersen, Henrik Sorensen, Henrik Pranov