Abstract: A process, system and medium for detecting anomalous authentication requests to a protected resource during an authentication journey, in order to regulate step-up authentication are described. The process includes obtaining request features from the authentication request that triggered the authentication journey. The process includes processing, by an ensemble of Machine Learning (ML) models and a set of rule-based heuristics, a set of features based on the request features, the set of features associated with a userID. The process includes deriving risk sub-scores for each ML model and each heuristic. The process includes deriving a risk score based on the risk sub-scores. The process includes determining that the risk score exceeds an explanation-triggering threshold. The process includes providing, to a node in the authentication journey, the risk score with an explanation of the risk score. The system and medium are configured to execute the process, and configured to provide the explanation.

Abstract: A process, system and medium for building a training set and performing supervised training of a Machine Learning (ML) model that determines a risk score used to decide whether to impose stepped up authentication during an authentication journey are described. The process includes selecting examples of completed authentication journeys, including failed and successful authentication outcomes after step-up requirements during the example journeys. The process includes pairing ground truth outcomes from the example journeys with authentication request features initially available prior to imposition of the step-up requirements to produce request feature-outcome pairs. The process includes using at least the request feature-outcome pairs to perform the supervised training of the ML model to determine a risk score that can be used to decide whether to impose the stepped up authentication during an authentication journey. The system and medium are configured to execute the process.

Abstract: A process, system and medium for conditional invocation of step-up authentication based on anomalous requests during an authentication journey, without burdening legitimate users, are described. The process includes sending features of an authentication request, ostensibly from a user, and a userID of the user, to an access prediction service. The process includes receiving feedback from the access prediction service, the feedback comprising a risk score and an explanation of the risk score. The process includes finding, based on the risk score, that the authentication request is anomalous for the userID. The process includes, based on the finding that the authentication request is anomalous and the explanation, determining whether to invoke step-up authentication. In some implementations, the determining does not invoke step-up authentication, whereby the ostensible user is not challenged despite the finding of anomaly. The system and medium are configured to execute the process.

Abstract: The disclosed technology teaches aggregating 3rd-party risk measures during an authentication journey, including providing a risk measure aggregation node, a JSON transform, and a configuration for 3rd-party risk measures to request. Responsive to invocation of the risk measure aggregation node during the authentication journey, the method includes setting a timer for receipt of a configured 3rd-party risk measure, wherein expiration of the timer causes the risk measure aggregation node to stop waiting for a timed-out 3rd party risk measure provider and requesting the configured 3rd-party risk measures. Upon receiving at least some of the requested 3rd-party risk measures, included is applying the JSON transform to aggregate the returned 3rd-party risk measures into an aggregate score, and the risk measure aggregation node providing to another node in the authentication journey an aggregated score taking into account the configured 3rd-party risk measures received prior to expiration of the timer.

Abstract: The disclosed technology teaches aggregating 3rd-party risk measures during an authentication journey, including providing a risk measure aggregation node, a JSON transform, and a configuration for 3rd-party risk measures to request. Responsive to invocation of the risk measure aggregation node during the authentication journey, the method includes setting a timer for receipt of a configured 3rd-party risk measure, wherein expiration of the timer causes the risk measure aggregation node to stop waiting for a timed-out 3rd party risk measure provider and requesting the configured 3rd-party risk measures. Upon receiving at least some of the requested 3rd-party risk measures, included is applying the JSON transform to aggregate the returned 3rd-party risk measures into an aggregate score, and the risk measure aggregation node providing to another node in the authentication journey an aggregated score taking into account the configured 3rd-party risk measures received prior to expiration of the timer.

Abstract: The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the tyrosine kinase enzymatic activity of the Abelson protein (ABL1), the Abelson-related protein (ABL2) and related chimeric proteins, in particular BCR-ABL1. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.

Abstract: The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the tyrosine kinase enzymatic activity of the Abelson protein (ABL1), the Abelson-related protein (ABL2) and related chimeric proteins, in particular BCR-ABL1. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.

Abstract: The present invention relates to compounds of formula I: in which Y, Y1, Y4, Y5, Y6, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.

Abstract: The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the tyrosine kinase enzymatic activity of the Abelson protein (ABL1), the Abelson-related protein (ABL2) and related chimeric proteins, in particular BCR-ABL1. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.

Abstract: The present invention relates to compounds of formula I: in which Y, Y1, Y4, Y5, Y6, R1, R2, R3 and R4 are defined in the Summary of the Invention; capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.

Abstract: The atmospheric water harvester (2) shown in FIG. (1) comprises a centrally located flue in the form of a tower 4 and a surrounding heating enclosure (6) for collecting incident solar energy to heat air which enters its periphery (8). With heating of the air in the heating enclosure (6), an updraught is created within tower (4) as the air from the heating enclosure (6) returns to the atmosphere from the open end of the tower A base structure (10) housing a plurality of wind turbines is provided around the base of the tower. As the heated air flows from the heating enclosure (6) into the tower it is harnessed to rotate the wind turbines. Each wind turbine (20) is provided with associated water collection apparatus (94) comprising a refrigeration system for cooling condensation surfaces to, or below, the dew point of the air to effect the condensation of water from the air onto condensation surfaces of the water collection apparatus for collection.

Abstract: A pacifier locator system comprising a pacifier including a housing, a speaker located within said housing, a light source associated with said pacifier, a transmitter capable of transmitting at least one signal and a receiver associated with said pacifier, wherein said speaker emits an audible tone upon receiving said at least one signal and wherein said light source emits a visual signal upon receiving said at least one signal.

Abstract: A automated toilet seat lowering device for lowering a raised toilet seat after a predetermined amount of time. The automated toilet seat lowering device includes a motor for rotating a spindle securely attached to a toilet seat. The motor is mechanically coupled to the spindle. The spindle is generally coaxial with hinges hingedly coupling the toilet seat to the toilet. The motor rotates the spindle to lower the toilet seat downward from a raised position. A housing is mountable to a wall. The housing has a front side facing outwardly away from the wall. Control circuitry adapted for actuating the motor, tracking elapsed time and receiving an electrical signal from a sensor is positioned in the housing and electrically coupled to the motor. A sensor for detecting motion is positioned on the front side of the housing is electrically coupled to the control circuitry. The sensor sends electrical signals to the control circuitry when the sensor detects movement.