Patents by Inventor Darryl Lynn McDougald

Darryl Lynn McDougald has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RADIOHALOGEN PROSTHETIC MOIETIES AND RADIOLABELED BIOMOLECULES
    Publication number: 20230002293
    Abstract: The application is drawn to radiohalogen prosthetic moieties and precursors thereof and to radiolabeled biomolecules comprising such radiohalogen prosthetic moieties. The biomolecules have an affinity for particular types of cells and may specifically bind a certain cell, such as a cancer cell. Relevant biomolecules include antibodies, monoclonal antibodies, antibody fragments, peptides, other proteins, nanoparticles, aptamers, and pharamacological moieties used to target prostate-specific membrane antigen (PSMA).
    Type: Application
    Filed: November 11, 2020
    Publication date: January 5, 2023
    Inventors: Michael Rod Zalutsky, Ganesan Vaidyanathan, Darryl Lynn McDougald
  • Chemical compounds
    Patent number: 8673948
    Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: March 18, 2014
    Assignee: GlaxoSmithKline, LLC
    Inventors: Philip Stewart Turnbull, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
  • CHEMICAL COMPOUNDS
    Publication number: 20110301203
    Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.
    Type: Application
    Filed: August 19, 2011
    Publication date: December 8, 2011
    Applicant: GLAXOSMITHKLINE LLC
    Inventors: Philip Stewart Turnbull, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
  • Chemical compounds
    Patent number: 8026262
    Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: September 27, 2011
    Assignee: GlaxoSmithKline LLC
    Inventors: Philip Stewart Turnbull, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
  • CHEMICAL COMPOUNDS
    Publication number: 20090264482
    Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.
    Type: Application
    Filed: July 1, 2009
    Publication date: October 22, 2009
    Applicant: SMITHKLINE BEECHAM CORPORATION
    Inventors: Philip Stewart Turnbull, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
  • Chemical compounds
    Patent number: 7572820
    Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.
    Type: Grant
    Filed: September 27, 2007
    Date of Patent: August 11, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Philip Stewart Turnbull, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
  • CHEMICAL COMPOUNDS
    Publication number: 20080139631
    Abstract: This invention relates to non-steroidal compounds that are modulators of androgen receptor, and also to the methods for the making and use of such compounds.
    Type: Application
    Filed: September 27, 2007
    Publication date: June 12, 2008
    Applicant: SmithKline Beecham Corporation
    Inventors: Philip Stewart TURNBULL, Rodolfo Cadilla, Andrew Larkin, Huiquiang Zhou, Eugene L. Stewart, Katherine Stetson, Darryl Lynn McDougald, Amarjit Sab Randhawa, John A. Ray
  • Pyrrolidines as dipeptidyl peptidase inhibitors
    Patent number: 7196201
    Abstract: The present invention relates to novel compounds, their use for inhibiting serine proteases, such as dipeptidyl peptidases, such as dipeptidyl peptidase IV (DPP-IV) and to methods for their production and their therapeutic utility
    Type: Grant
    Filed: June 26, 2002
    Date of Patent: March 27, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Curt Dale Haffner, Darryl Lynn McDougald, Amarjit Sab Randhawa, Steven Michael Reister, David N Deaton
  • Fluoropyrrolidines as dipeptidyl peptidase inhibitors
    Patent number: 7183290
    Abstract: The present invention relates to novel compounds, their use for inhibiting post prolin/analine-cleaving proteases, such as serine proteases, such as dipeptidyl peptidases, such as dipeptidyl peptidase IV (DPP-IV), and to methods for their production and their therapeutic utility.
    Type: Grant
    Filed: June 26, 2002
    Date of Patent: February 27, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Curt Dale Haffner, Darryl Lynn McDougald, James Martin Lenhard
  • Selective RXR ligands
    Patent number: 7173134
    Abstract: The present invention includes novel retinoid compounds that have selectivity as RXR agonists on one or more isoforms of RXR, currently, RXR?, RXR?, or RXR?. The present compounds, and pharmaceutical compositions incorporating these compounds, therefore, are effective in treating conditions mediated by RXRs. Among other physiological responses, the compounds of the present invention reduce blood glucose and maintain body weight, and, thus, are useful for the treatment of diabetes (NIDDIM) and obesity.
    Type: Grant
    Filed: September 16, 2002
    Date of Patent: February 6, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Curt Dale Haffner, Istvan Kaldor, Darryl Lynn McDougald, Aaron Bayne Miller
  • Fluoropyrrolidines as dipeptidyl peptidase inhibitors
    Patent number: 7132443
    Abstract: The present invention relates to novel compounds, their use for inhibiting serine proteases, such as dipeptidyl peptidases, such as dipeptidyl peptidase IV (DPP-IV) and to methods for their production and their therapeutic utility.
    Type: Grant
    Filed: June 26, 2002
    Date of Patent: November 7, 2006
    Assignee: SmithKlineBeecham Corporation
    Inventors: Curt Dale Haffner, Darryl Lynn McDougald, Amarjit Sab Randhawa, Steven Michael Reister, James Martin Lenhard
  • Fluoropyrrolidines as dipeptidyl peptidase inhibitors
    Publication number: 20040242636
    Abstract: The present invention relates to novel compounds, their use for inhibiting post prolin/analine-cleaving proteases, such as serine proteases, such as dipeptidyl peptidases, such as dipeptidyl peptidase IV (DPP-IV), and to methods for their production and their therapeutic utility.
    Type: Application
    Filed: December 19, 2003
    Publication date: December 2, 2004
    Inventors: Curt Dale Haffner, Darryl Lynn McDougald, James Martin Lenhard
  • Selective rxr ligands
    Publication number: 20040198980
    Abstract: The present invention includes novel retinoid compounds that have selectivity as RXR agonists on one or more isoforms of RXR, currently, RXR&agr;, RXR&bgr;, or RXR&ggr;. The present compounds, and pharmaceutical compositions incorporating these compounds, therefore, are effective in treating conditions mediated by RXRs. Among other physiological responses, the compounds of the present invention reduce blood glucose and maintain body weight, and, thus, are useful for the treatment of diabetes (NIDDIM) and obesity.
    Type: Application
    Filed: March 25, 2004
    Publication date: October 7, 2004
    Inventors: Curt Dale Haffner, Istvan Kaldor, Darryl Lynn McDougald
  • Fluoropyrrolidines as dipeptidyl peptidase inhibitors
    Publication number: 20040171848
    Abstract: The present invention relates to novel compounds, their use for inhibiting serine proteases, such as dipeptidyl peptidases, such as dipeptidyl peptidase IV (DPP-IV) and to methods for their production and their therapeutic utility.
    Type: Application
    Filed: December 19, 2003
    Publication date: September 2, 2004
    Inventors: Curt Dale Haffner, Darryl Lynn McDougald, Amarjit Sab Randhawa, Steven Michael Reister, James Martin Lenhard
  • Pyrrolidines as dipeptidyl peptidase inhibitors
    Publication number: 20040167341
    Abstract: The present invention relates to novel compounds of formula (I):, their use for inhibiting serine proteases, such as dipeptidyl peptidases, such as dipeptidyl peptidase IV (DPP-IV) and to methods for their production and their therapeutic utility.
    Type: Application
    Filed: December 19, 2003
    Publication date: August 26, 2004
    Inventors: Curt Dale Haffner, Darryl Lynn McDougald, Armarjit Sab Randhawa, Steven Michael Reister, David N Deaton, Martin James Lenhard