Patents by Inventor Darryl Y. Nishimura

Darryl Y. Nishimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITION COMPRISING AN ANTI-OXIDANT TO PRESERVE CORNEAL TISSUE
    Publication number: 20220249399
    Abstract: A composition comprising an amount of an anti-oxidant comprising one or more of ubiquinol, MitoQ, vitamin E, vitamin C, ascorbate-2-phosphate, idebenone, pyrroloquinoline quinone (PQQ), N-acetyl-L-cysteine (NAC), palmitate, reduced glutathione, or a C14-C18 saturated fatty acid effective to preserve, e.g., corneal tissue, and methods of using the composition, are provided.
    Type: Application
    Filed: March 4, 2020
    Publication date: August 11, 2022
    Inventors: Aliasger K. Salem, Youssef Wahib Naguib lbrahim, Somaya Ali Mohammed Elsaid Abdelrahman, Jessica M. Skeie, Benjamin T. Aldrich, Gregory Schmidt, Cynthia R. Reed, Mark A. Greiner, Darryl Y. Nishimura, Sanjib Saha
  • Identification of a gene causing the most common form of bardet-biedl syndrome and uses thereof
    Patent number: 6962788
    Abstract: The present invention relates to the identification of a gene, mutated at the most common locus now designated BBS1, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypogonadism, mental retardation, renal cancer and other renal abnormalities, retinopathy and polydactyly or limb deformities. The human BBS1 protein disclosed herein is composed of 17 exons and spans approximately 23 kb. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described.
    Type: Grant
    Filed: May 28, 2003
    Date of Patent: November 8, 2005
    Assignee: University of Iowa Research Foundation
    Inventors: Val C. Sheffield, Kirk Mykytyn, Darryl Y. Nishimura, Edwin M. Stone, Charles C. Searby
  • Identification of a gene causing the most common form of Bardet-Biedl Syndrome and uses thereof
    Publication number: 20030232375
    Abstract: The present invention relates to the identification of a gene, mutated at the most common locus now designated BBS1, that is involved in the genetic disease Bardet Biedl Syndrome (BBS), which is characterized by such diverse symptoms as obesity, diabetes, hypogonadism, mental retardation, renal cancer and other renal abnormalities, retinopathy and polydactyly or limb deformities. The human BBS1 protein disclosed herein is composed of 17 exons and spans approximately 23 kb. Methods of use for the gene, for example in diagnosis and therapy of BBS and in drug screening, also are described.
    Type: Application
    Filed: May 28, 2003
    Publication date: December 18, 2003
    Applicant: The University of Iowa Research Foundation
    Inventors: Val C. Sheffield, Kirk Mykytyn, Darryl Y. Nishimura, Edwin M. Stone, Charles C. Searby