Abstract: A carrier pre-encoded with information sufficient to distinguish it from a heterogeneous population of carriers is disclosed on which a compound can be synthesised. The carrier has two attributes integrally associated therewith, which attributes are detectable and/or quantifiable during synthesis of the compound and which define a code identifying the carrier before, during and after said synthesis, with the proviso that one of said attributes is other than shape, or surface deformation(s) of the carrier. The invention also encompasses a plurality of carriers that are pre-encoded as above and a method of synthesising and deconvoluting a combinatorial library using such carriers.

Abstract: An assembly of a carrier having one or more reporter beads non-covalently attached thereto which may be used in relation to oligomer libraries. The oligomer libraries may be formed by a combinatorial split-process-recombine procedure. The oligomer library comprises a plurality of molecules comprising a multiplicity of different chemical groups. Each reporter bead has a different marker associated therewith to identify the chemical group attached to the carrier as well as to identify the position in sequence of the chemical group relative to other chemical groups in each molecule of the library. The markers are selected from fluorophores, chromophores, bar codes or radioactive or luminescent labels.

Abstract: The present invention is directed to the use of at least one secondary subunit sequence that varies from a primary subunit sequence by the addition, deletion and/or substitution of at least one subunit for inferring information about the primary subunit sequence. The invention is also directed to the use of such variant sequences for wholly or partially executing a task on an primary subunit sequence, which in one embodiment is refractory to the execution of that task and more particularly to the use of such sequence(s) for wholly or partially deducing the sequence of a primary subunit sequence. In a preferred embodiment of the present invention, the variant sequences are generated by mutagenesis techniques. The subject invention further relates to a method, which is optionally implemented by a processing system, for designing secondary subunit sequences.