Abstract: Provided herein is a tablet comprising 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol or a pharmaceutically acceptable salt thereof.

Abstract: The invention relates to a reinforcing beam for a vehicle, adapted to constitute at least a portion of a heating, ventilation and air conditioning assembly. It includes at least one air inlet, at least one air outlet and an air channel in-between. The reinforcing beam includes also a primary insert and a plastic body, the primary insert and the plastic body being connected with one another.

Abstract: A HVAC system (100) includes a housing (10) with at least one first inlet (20) and at least one second inlet (30) formed thereon, at least one first door (20a), at least one second door (30a) and an intermediate door (40). The first inlet (20) and the second inlet (30) is for ingress of a first fluid stream and a second fluid stream inside the housing (10). The first door (20a) and the second door (30a) moves with respect to the first inlet (20) and the second inlet (30) respectively to define an open configuration, a closed configuration and a partially open configuration thereof. The intermediate door (40) is disposed between the first inlet (20) and the second inlet (30) and moves between a deployed and an un-deployed configuration to respectively disrupt and allow fluid flow there across. The intermediate door (40) is a sliding door.

Abstract: A HVAC system (100) includes a housing (10) with at least one first inlet (20) and at least one second inlet (30) formed thereon, at least one first door (20a), at least one second door (30a) and an intermediate door (40). The first inlet (20) and the second inlet (30) is for ingress of a first fluid stream and a second fluid stream inside the housing (10). The first door (20a) and the second door (30a) moves with respect to the first inlet (20) and the second inlet (30) respectively to define an open configuration, a closed configuration and a partially open configuration thereof. The intermediate door (40) is disposed between the first inlet (20) and the second inlet (30) and moves between a deployed and an un-deployed configuration to respectively disrupt and allow fluid flow there across. The intermediate door (40) is a sliding door.

Abstract: Provided herein is a tablet comprising 2-methyl-1-[(4-[-6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol or a pharmaceutically acceptable salt thereof.

Abstract: A heating, ventilation, and air-conditioning (HVAC) assembly for managing air mixing door kinematics of a motor vehicle is disclosed. The assembly includes a first door configured for allowing passage of a first air flow, a second door configured for allowing passage of a second air flow, obtaining means configured to obtain a temperature command indicating a target temperature for a passenger cabin, identifying means configured to identify a pattern of non-linear door kinematics for mixing the first air flow and the second air flow based on the temperature command, coordinating means configured to coordinate the non-linear door kinematics between the first door and the second door, and mixing means configured to mix the first air flow and the second air flow.

Abstract: Provided herein is a tablet comprising 2-methyl-1-[(4-[6-(trifluoromethyl)pyridin-2-yl]-6-{[2-(trifluoromethyl)pyridin-4-yl]amino}-1,3,5-triazin-2-yl)amino]propan-2-ol or a pharmaceutically acceptable salt thereof.

Abstract: A split heating, ventilation, and air-conditioning (HVAC) assembly for a motor vehicle is disclosed. The split HVAC includes a first sub-assembly comprising an evaporator and a first airflow space, a second sub-assembly comprising a second airflow space, a single sealing element located between a wall and one of the first sub-assembly or the second-sub-assembly, and a first interfacing element that directly connects the first sub-assembly and the second sub-assembly. The single sealing element and the first interfacing element prevent any airflow leakage from both the first sub-assembly and the second sub-assembly, and one of the first sub-assembly and the second sub-assembly extends partially into the other of the first sub-assembly and the second sub-assembly.

Abstract: A Heating, Ventilation, and Air-Conditioning unit for a vehicle is provided. The HVAC unit comprises a housing, a first inlet, a second inlet first flap, and a third door. The first flap having a first door and a second door, attached to the first inlet. The first door is angularly movable with respect to the second door and adapted to move between a first position and a second position to open and close the first inlet. Further, the second door is angularly movable with respect to the first door and adapted to move between the first position and a third position to open and close air passage between the first inlet and the second inlet. The third door rotatably connected in the second inlet, and is movable between a closed position where the second inlet is closed and at least partially open position where the second inlet is partially open.

Abstract: A heating, ventilation, and air-conditioning (HVAC) assembly for supplying different mixed air flows simultaneously is disclosed. The assembly includes first blend kinematics configured for allowing passage of a first air flow, second blend kinematics configured for allowing passage of a second air flow, obtaining means configured to obtain a temperature command indicating a target temperature for two different locations outside the HVAC assembly, identifying means configured to identify a pattern for the first blend kinematics and the second blend kinematics for modifying the first air flow and the second air flow based on the temperature command, and coordinating means configured to coordinate each of the first blend kinematics and the second blend kinematics simultaneously.

Abstract: A system for controlling movements of doors of an HVAC module includes an actuation gear and an intermediate cam. A main door includes a first portion and a second portion having a first guide. The first portion engages with actuation gear to enable linear movement of the main door. A slave door includes a second engagement element and moves between a blocking and unblocking position based on movement of main door. The intermediate cam moves angularly and includes a first engagement element and a second guide. The first engagement element interacts with the first guide, and the second guide interacts with second engagement element to facilitate angular movement of slave door in response to movement of the main door. The first guide includes a bend positioned to enable angular movement of the slave door after the main door moves a pre-determined distance.

Abstract: A heating, ventilation, and air-conditioning (HVAC) assembly for supplying different mixed air flows simultaneously is disclosed. The assembly includes first blend kinematics configured for allowing passage of a first air flow, second blend kinematics configured for allowing passage of a second air flow, obtaining means configured to obtain a temperature command indicating a target temperature for two different locations outside the HVAC assembly, identifying means configured to identify a pattern for the first blend kinematics and the second blend kinematics for modifying the first air flow and the second air flow based on the temperature command, and coordinating means configured to coordinate each of the first blend kinematics and the second blend kinematics simultaneously.

Abstract: A heating, ventilation, and air-conditioning (HVAC) assembly for managing air mixing door kinematics of a motor vehicle is disclosed. The assembly includes a first door configured for allowing passage of a first air flow, a second door configured for allowing passage of a second air flow, obtaining means configured to obtain a temperature command indicating a target temperature for a passenger cabin, identifying means configured to identify a pattern of non-linear door kinematics for mixing the first air flow and the second air flow based on the temperature command, coordinating means configured to coordinate the non-linear door kinematics between the first door and the second door, and mixing means configured to mix the first air flow and the second air flow.

Abstract: A method for smart heating and Recirculation Air Management (RAM) using an HVAC assembly for a vehicle is disclosed. The method involves obtaining a first air pressure at a first fresh air inlet configured for allowing passage of fresh air in proportion to a first degree of aperture of the first fresh air inlet and the first air pressure, obtaining a second air pressure at a first recycled air inlet configured for allowing passage of recycled air in proportion to a second degree of aperture of the first recycled air inlet and the second air pressure, identifying a required mixed air pressure based on a combination of the first air pressure and the second air pressure, and dynamically modifying the first and second degrees of aperture to obtain the required mixed air pressure which remains constant regardless of parameters associated with the inside passenger cabin of the vehicle.

Abstract: An HVAC air inlet housing for a vehicle includes an air inlet housing having a top portion and a bottom portion. A fresh air duct, to convey fresh air from an air inlet to a blower, is defined by the air inlet housing. A water inlet port, to connect to an evaporator drain port via a hose, is defined in the bottom portion. The hose is to convey water from the evaporator drain port to the water inlet port. A water tunnel is defined by the air inlet housing to convey water from the water inlet port to a sluice defined in the bottom portion. The sluice is to convey water from the water tunnel to a sump defined in the bottom portion. A sump drain port is defined in the air inlet housing bottom portion in fluid communication with the sump to drain water from the sump.

Abstract: A system for controlling movements of doors of an HVAC module includes an actuation gear and an intermediate cam. A main door includes a first portion and a second portion having a first guide. The first portion engages with actuation gear to enable linear movement of the main door. A slave door includes a second engagement element and moves between a blocking and unblocking position based on movement of main door. The intermediate cam moves angularly and includes a first engagement element and a second guide. The first engagement element interacts with the first guide, and the second guide interacts with second engagement element to facilitate angular movement of slave door in response to movement of the main door. The first guide includes a bend positioned to enable angular movement of the slave door after the main door moves a pre-determined distance.

Abstract: A split heating, ventilation, and air-conditioning (HVAC) assembly for a motor vehicle is disclosed. The split HVAC includes a first sub-assembly comprising an evaporator and a first airflow space, a second sub-assembly comprising a second airflow space, a single sealing element located between a wall and one of the first sub-assembly or the second-sub-assembly, and a first interfacing element that directly connects the first sub-assembly and the second sub-assembly. The single sealing element and the first interfacing element prevent any airflow leakage from both the first sub-assembly and the second sub-assembly, and one of the first sub-assembly and the second sub-assembly extends partially into the other of the first sub-assembly and the second sub-assembly.

Abstract: An HVAC air inlet housing for a vehicle includes an air inlet housing having a top portion and a bottom portion. A fresh air duct, to convey fresh air from an air inlet to a blower, is defined by the air inlet housing. A water inlet port, to connect to an evaporator drain port via a hose, is defined in the bottom portion. The hose is to convey water from the evaporator drain port to the water inlet port. A water tunnel is defined by the air inlet housing to convey water from the water inlet port to a sluice defined in the bottom portion. The sluice is to convey water from the water tunnel to a sump defined in the bottom portion. A sump drain port is defined in the air inlet housing bottom portion in fluid communication with the sump to drain water from the sump.

Abstract: Pharmaceutical compositions and single unit dosage forms of (S)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione, or a pharmaceutically acceptable stereoisomer, prodrug, salt, solvate, hydrate, or clathrate, are provided herein. Also provided are methods of treating, managing, or preventing various disorders, such as cancer, an inflammatory disease and/or an immune-related disorder.