Patents by Inventor Darshin S. Patel

Darshin S. Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250114199
    Abstract: A delivery system for delivering a stent-mounted heart valve, or other implant, through an introducer sheath. The delivery system includes an elongate catheter supporting a capsule. The capsule contains the stent-mounted heart valve in the crimped condition. The capsule includes a protrusion extending from its outer surface for urging the sheath away from the outer surface capsule as it moves therethrough, thereby reducing an average peak push force resulting from advancement of the capsule through the sheath.
    Type: Application
    Filed: December 19, 2024
    Publication date: April 10, 2025
    Applicant: EDWARDS LIFESCIENCES CORPORATION
    Inventor: Darshin S. Patel
  • Publication number: 20250090797
    Abstract: Devices and methods for selectively directing fluid flow through lumens of a catheter in order to effectively flush and/or de-air specified lumens of the catheter are disclosed. As one example, an assembly comprises a catheter including a first shaft and a second shaft extending through the first shaft. The assembly further comprises a sealing mechanism including a first seal disposed around a distal end portion of the first shaft, a second seal disposed around a portion of the second shaft that extends distal to the first shaft, and a cavity disposed within a housing of the sealing mechanism between the first seal and the second seal. A distal end of the first shaft is disposed within the cavity and the cavity is fluidly sealed by the first seal and the second seal such that fluid from a first lumen of the first shaft cannot exit the cavity.
    Type: Application
    Filed: December 4, 2024
    Publication date: March 20, 2025
    Inventors: Kurt Kelly Reed, Kevin Gantz, Darshin S. Patel
  • Patent number: 12208004
    Abstract: A delivery system for delivering a stent-mounted heart valve, or other implant, through an introducer sheath. The delivery system includes an elongate catheter supporting a capsule. The capsule contains the stent-mounted heart valve in the crimped condition. The capsule includes a protrusion extending from its outer surface for urging the sheath away from the outer surface capsule as it moves therethrough, thereby reducing an average peak push force resulting from advancement of the capsule through the sheath.
    Type: Grant
    Filed: July 28, 2022
    Date of Patent: January 28, 2025
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventor: Darshin S. Patel
  • Publication number: 20250009507
    Abstract: Devices and methods for providing a reservoir of fluid within a handle of a guide catheter are disclosed. As one example, a delivery apparatus can include a handle including a proximal segment including one or more fluid seals mounted within the proximal segment, an intermediate segment disposed adjacent and distal to the proximal segment, the intermediate segment including an inner surface defining a first lumen having a first inner diameter, and a distal segment disposed adjacent and distal to the intermediate segment. The delivery apparatus can further include a shaft extending distally from the handle, the shaft including a second lumen extending between a distal end and a proximal end of the shaft, the second lumen including a second inner diameter that is smaller than the first inner diameter of the first lumen.
    Type: Application
    Filed: September 13, 2024
    Publication date: January 9, 2025
    Inventors: Kevin Jiang, Darshin S. Patel, Kurt Kelly Reed
  • Publication number: 20240398537
    Abstract: In a particular embodiment, the present disclosure provides a prosthetic valve delivery assembly that includes a storage tube and a nose cone cap. A prosthetic valve having a frame is at least partially disposed within the storage tube. A nose cone is disposed about an elongated shaft. The nose cone cap and the storage tube have mating first and second locking member that can be coupled to selectively secure the nose cone cap to the storage tube.
    Type: Application
    Filed: August 16, 2024
    Publication date: December 5, 2024
    Inventors: Alexander H. Cooper, Michael R. Bialas, David M. Taylor, Gregory Scott Tyler, II, Zachary R. Kowalski, Art Z. Kwan, Darshin S. Patel, Asher L. Metchik, Michael J. Popp, Amanda Kristine Anderson White
  • Patent number: 12090036
    Abstract: In a particular embodiment, the present disclosure provides a prosthetic valve delivery assembly that includes a storage tube and a nose cone cap. A prosthetic valve having a frame is at least partially disposed within the storage tube. A nose cone is disposed about an elongated shaft. The nose cone cap and the storage tube have mating first and second locking member that can be coupled to selectively secure the nose cone cap to the storage tube.
    Type: Grant
    Filed: March 11, 2022
    Date of Patent: September 17, 2024
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Alexander H. Cooper, Michael R. Bialas, David M. Taylor, Gregory Scott Tyler, II, Zachary R. Kowalski, Art Z. Kwan, Darshin S. Patel, Asher L. Metchik, Michael J. Popp, Amanda Kristine Anderson White
  • Publication number: 20240189098
    Abstract: A prosthetic heart valve has a frame including a plurality of strut members, the frame being radially expandable and collapsible between a collapsed state and an expanded state, the frame having an inflow end and an outflow end and defining a longitudinal axis. A leaflet structure is situated at least partially within the frame. A covering is disposed around an exterior of the frame and includes a cushioning layer, a first strip of material coupled to the cushioning layer and folded to encapsulate apices of the strut members of the inflow end of the frame, and a second strip of material coupled to the cushioning layer and folded to encapsulate apices of the strut members of the outflow end of the frame. The cushioning layer includes texturized filaments that provide compressible volume and a plush surface to the cushioning layer when the frame is in the expanded state.
    Type: Application
    Filed: February 15, 2024
    Publication date: June 13, 2024
    Inventors: Sara Tzadok, Khen Perlmutter, Darshin S. Patel, Boaz Manash, Ajay Chadha, Waina Michelle Chu, Chambory Chhe, Evan T. Schwartz, Sandip Vasant Pawar
  • Patent number: 11938021
    Abstract: A prosthetic heart valve has a frame including a plurality of strut members, an inflow end, and an outflow end. A leaflet structure is situated at least partially within the frame, and a covering is disposed around an exterior of the frame. The covering includes a cushioning layer, and a first strip member folded over an inflow circumferential edge portion of the cushioning layer to form a first protective portion. A second strip member is folded over an outflow circumferential edge portion of the cushioning layer to form a second protective portion. The first strip member and the second strip member are spaced apart from each other along a longitudinal axis of the prosthetic heart valve.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: March 26, 2024
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Sara Tzadok, Khen Perlmutter, Darshin S. Patel, Boaz Manash, Ajay Chadha, Waina Michelle Chu, Chambory Chhe, Evan T. Schwartz, Sandip Vasant Pawar
  • Publication number: 20230414350
    Abstract: A prosthetic implant delivery assembly includes a prosthetic implant and a catheter. The prosthetic implant includes a plurality of apices with apertures. Each apex of the plurality of apices is circumferentially-spaced apart relative to an adjacent apex. The catheter includes a plurality of arms and a plurality of locking elements. Each of the arms includes an opening configured to receive a respective apex of the prosthetic implant. Each of the locking elements is configured to extend through the aperture of a respective apex of the prosthetic implant. A length of at least one of the locking elements is different than a length of another locking element such that when the prosthetic implant is coupled to the catheter by the locking elements, a longitudinal axis of the prosthetic implant can be held at a tilted position relative to a longitudinal axis of the catheter.
    Type: Application
    Filed: September 10, 2023
    Publication date: December 28, 2023
    Inventors: John J. Desrosiers, Amanda Kristine Anderson White, Michael R. Bialas, Gilbert Madrid, Michael J. Popp, Thanh V. Nguyen, Jun Liu, Asher L. Metchik, Darshin S. Patel
  • Patent number: 11801133
    Abstract: Docking devices for docking a prosthetic valve at a native valve of a heart can include a coiled docking anchor and a retrieval suture. The docking device and retrieval suture can be configured for improved retention and retrieval of the docking device after deployment. The docking devices can have an end portion with a central axis. The retrieval suture can be connected to the end portion such that a line of force applied by applying tension to the retrieval suture is substantially aligned with the central axis.
    Type: Grant
    Filed: July 20, 2020
    Date of Patent: October 31, 2023
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Darshin S. Patel, Boaz Manash, Khen Perlmutter, Eyal Leiba, Yoav Rozen, Dinesh L. Sirimanne, Tri D. Tran, Jocelyn Chau, Noa Axelrod Manela, Zohar Kiblitski
  • Publication number: 20230329851
    Abstract: A container configured to receive a dock assembly therein for packaging is disclosed. The container can include: a base defining an engagement surface configured to receive the dock assembly; a lid configured to releasably engage with the base such that at least a portion of the dock assembly is disposed between the base and the lid; and a dock holder affixed to the container and configured to receive a first portion of the dock assembly comprising two or more adjacent coils thereon. The dock holder can comprise a protrusion configured to engage the first portion of the dock assembly and space a second portion of the dock assembly away from the dock holder.
    Type: Application
    Filed: June 9, 2023
    Publication date: October 19, 2023
    Inventors: Jason Seng-Che Lam, Darshin S. Patel, Alyssa Joy Hamm (formerly Gross), Yuanlong Du, Jocelyn Chau, Sean Chow, Vipul P. Rajpara
  • Publication number: 20230310152
    Abstract: A docking device for docking a prosthetic valve at a native valve of a heart can include a coil comprising a plurality of turns and having a proximal end and distal end. The docking device can further include a first covering disposed around and covering the coil from the distal end to the proximal end of the coil, and a second covering disposed over the first covering. A distal end and proximal end of the second covering are spaced away from a distal end and proximal end, respectively, of the first covering.
    Type: Application
    Filed: June 6, 2023
    Publication date: October 5, 2023
    Inventors: Darshin S. Patel, Boaz Manash, Khen Perlmutter, Eyal Leiba, Yoav Rozen, Dinesh L. Sirimanne, Tri D. Tran, Jocelyn Chau, Noa Axelrod Manela, Zohar Kiblitski
  • Publication number: 20230285141
    Abstract: A docking device for docking a prosthetic valve at a native valve of a heart includes a coiled body and a high friction sleeve. The coiled body has an upper region, a central region, and a lower region. The docking device is configured to be implanted at the native valve with the upper region positioned in a first chamber of the heart, the lower region positioned in a second chamber of the heart, and the central region positioned to extend around a plurality of leaflets of the native valve. A high friction sleeve covers at least a portion of the central region. The high friction sleeve comprises a material configured to generate more friction between the prosthetic valve and the docking device than an exterior surface of the coiled body.
    Type: Application
    Filed: May 19, 2023
    Publication date: September 14, 2023
    Inventors: Darshin S. Patel, Hernan Altman, Boaz Manash, Tamir S. Levi, Dinesh L. Sirimanne
  • Publication number: 20230270540
    Abstract: A prosthetic heart valve can have one or more hermetic layers. The inner skirt and/or the outer skirt can comprise one or more hermetic layers, or the entire valve frame can be encapsulated within one or more hermetic layers. Each hermetic layer can be substantially nonporous or can have pores therein that are sized to discourage cellular ingrowth. The hermetic layer can prevent ingrowth of surrounding native tissue, thereby reducing pannus formation on the prosthetic leaflets. Alternatively or additionally, shapes of the leaflets of the valvular structure of the prosthetic valve and/or the coupling of the leaflets to the valve frame can be selected to avoid the incidence of stasis when implanted at a relatively low pressure gradient hemodynamic location. Such a prosthetic heart valve may reduce the risk of thrombosis.
    Type: Application
    Filed: May 9, 2023
    Publication date: August 31, 2023
    Inventors: Evan T. Schwartz, Darshin S. Patel, Jocelyn Chau, Hannah Reed Bettencourt
  • Publication number: 20230255754
    Abstract: Certain examples of the disclosure concern a docking device for securing a prosthetic valve at a native valve. The docking device includes a coil having a plurality of helical turns when deployed at the native valve, an expandable member extending radially outwardly from the coil and being movable between a radially-compressed/axially-elongated state and a radially-expanded/axially-foreshortened state, and a cover member surrounding an outer surface of the expandable member. A distal end portion of the cover member and a distal end portion of the expandable member are fixedly coupled to the coil via a distal suture including a plurality of knots and a plurality of wraps. A proximal end portion of the expandable member is fixedly coupled to a proximal end portion of the cover member. The proximal end portion of the expandable member and the proximal end portion of the cover member are axially movable relative to the coil.
    Type: Application
    Filed: April 21, 2023
    Publication date: August 17, 2023
    Inventors: Jocelyn Chau, Tram Ngoc Nguyen, Darshin S. Patel
  • Patent number: 11690708
    Abstract: Methods of implanting docking devices for prosthetic valves at a native heart valve include positioning a distal end of a delivery catheter into a first chamber of a heart, advancing a tubular body of a docking device from within the delivery catheter so that the distal end of the tubular body is advanced between native valve leaflets and positioned in a second chamber of the heart. The methods further include inserting a coil into a lumen of the docking device so that the tubular body adopts a configuration, releasing a proximal end of the docking device in the first chamber, inserting a replacement valve in an inner space of the docking device, and radially expanding the replacement valve until there is a retention force between the replacement valve and the docking device to hold the replacement valve in a stable position in the native valve.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: July 4, 2023
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Darshin S. Patel, Hernan Altman, Boaz Manash, Tamir S. Levi, Dinesh L. Sirimanne
  • Publication number: 20220362018
    Abstract: A delivery system for delivering a stent-mounted heart valve, or other implant, through an introducer sheath. The delivery system includes an elongate catheter supporting a capsule. The capsule contains the stent-mounted heart valve in the crimped condition. The capsule includes a protrusion extending from its outer surface for urging the sheath away from the outer surface capsule as it moves therethrough, thereby reducing an average peak push force resulting from advancement of the capsule through the sheath.
    Type: Application
    Filed: July 28, 2022
    Publication date: November 17, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventor: Darshin S. Patel
  • Publication number: 20220296352
    Abstract: In a particular embodiment, the present disclosure provides a prosthetic valve delivery assembly that includes a storage tube and a nose cone cap. A prosthetic valve having a frame is at least partially disposed within the storage tube. A nose cone is disposed about an elongated shaft. The nose cone cap and the storage tube have mating first and second locking member that can be coupled to selectively secure the nose cone cap to the storage tube.
    Type: Application
    Filed: March 11, 2022
    Publication date: September 22, 2022
    Inventors: Alexander H. Cooper, Michael R. Bialas, David M. Taylor, Gregory Scott Tyler, II, Zachary R. Kowalski, Art Z. Kwan, Darshin S. Patel, Asher L. Metchik, Michael J. Popp, Amanda Kristine Anderson White
  • Publication number: 20220287828
    Abstract: Anchoring or docking devices configured to be positioned at a native valve of a human heart and to provide structural support for docking a prosthetic valve therein. The docking devices can have coiled structures that define an inner space in which the prosthetic valve can be held. The docking devices can have enlarged end regions with circular or non-circular shapes, for example, to facilitate implantation of the docking device or to better hold the docking device in position once deployed. The docking devices can be laser-cut tubes with locking wires to assist in better maintaining a shape of the docking device. The docking devices can include various features to promote friction, such as frictional cover layers. Such docking devices can have ends configured to more securely attach the cover layers to cores of the docking devices.
    Type: Application
    Filed: May 27, 2022
    Publication date: September 15, 2022
    Inventors: Darshin S. Patel, Boaz Manash, Khen Perlmutter, Yoav Rozen, Dinesh L. Sirimanne, Zohar Kiblitski, Noa Axelrod Manela
  • Patent number: D1057152
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: January 7, 2025
    Assignee: EDWARDS LIFESCIENCES CORPORATION
    Inventors: Darshin S. Patel, Boaz Manash, Khen Perlmutter, Noa Axelrod Manela