Patents by Inventor Darwin R. Reyes-Hernandez

Darwin R. Reyes-Hernandez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REAL-TIME QUANTIFICATION METHOD OF CELL VIABILITY THROUGH SUPRAVITAL DYE UPTAKE USING LENS-FREE IMAGING SYSTEM
    Publication number: 20220170842
    Abstract: The inventive concept discloses a time series quantification method of supravital dye uptake of a cell using a lens-free imaging system.
    Type: Application
    Filed: November 30, 2020
    Publication date: June 2, 2022
    Applicants: SOL INC., Government of the United States of America, as Represented by the Secretary of Commerce
    Inventors: Jong Muk LEE, Darwin R. Reyes-Hernandez, Brian J. Nablo
  • Dual dielectropheretic membrane for monitoring cell migration
    Patent number: 10514359
    Abstract: A dual dielectropheretic article for monitoring cell migration includes: a membrane to selectively migrate a plurality of cells across the membrane, the membrane including: a first surface to receive the cells; a second surface opposed to the first surface; and a plurality of communication paths disposed in the membrane to provide the selective migration of the cells across the membrane from the first surface to the second surface; a first electrode disposed on the first surface to: provide an electric field for dielectrophoresis of the cells at the first surface; and provide a first potential for monitoring an impedance at the first surface; and a third electrode disposed on the second surface to: provide an electric field for dielectrophoresis of the cells at the second surface; and provide a third potential for monitoring an impedance at the second surface.
    Type: Grant
    Filed: November 16, 2016
    Date of Patent: December 24, 2019
    Assignee: GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE
    Inventors: Darwin R. Reyes-Hernandez, Brian Nablo
  • DUAL DIELECTROPHERETIC MEMBRANE FOR MONITORING CELL MIGRATION
    Publication number: 20170097319
    Abstract: A dual dielectropheretic article for monitoring cell migration includes: a membrane to selectively migrate a plurality of cells across the membrane, the membrane including: a first surface to receive the cells; a second surface opposed to the first surface; and a plurality of communication paths disposed in the membrane to provide the selective migration of the cells across the membrane from the first surface to the second surface; a first electrode disposed on the first surface to: provide an electric field for dielectrophoresis of the cells at the first surface; and provide a first potential for monitoring an impedance at the first surface; and a third electrode disposed on the second surface to: provide an electric field for dielectrophoresis of the cells at the second surface; and provide a third potential for monitoring an impedance at the second surface.
    Type: Application
    Filed: November 16, 2016
    Publication date: April 6, 2017
    Inventors: DARWIN R. REYES-HERNANDEZ, BRIAN NABLO
  • DIELECTROPHORETIC CELL CAPTURE
    Publication number: 20160018359
    Abstract: Various aspects are described for selectivity capturing cells or bioparticles on designated surfaces in dielectrophoretic systems and processes. A particular adhesive composition is described for enhancing cell retention. In addition, certain permeable polyester membranes used in the systems and processes are also described.
    Type: Application
    Filed: July 6, 2015
    Publication date: January 21, 2016
    Inventors: Michael Gaitan, John T. Elliott, Jennifer Hong Gordon, Darwin R. Reyes-Hernandez, Petra S. Dittrich, Conni Hanke
  • Dielectrophoretic cell capture
    Patent number: 9101939
    Abstract: Various aspects are described for selectivity capturing cells or bioparticles on designated surfaces in dielectrophoretic systems and processes. A particular adhesive composition is described for enhancing cell retention. In addition, certain permeable polyester membranes used in the systems and processes are also described.
    Type: Grant
    Filed: September 21, 2012
    Date of Patent: August 11, 2015
    Assignee: THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF COMMERCE, THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY
    Inventors: Michael Gaitan, John T. Elliott, Jennifer Hong Gordon, Darwin R. Reyes-Hernandez, Petra S. Dittrich, Conni Hanke