Abstract: A system and method for receiving, using one or more processors, one or more images associated with a user request, the one or more images including a first image, wherein the first image includes a facial image purported to be that of a valid document holder; determining, using the one or more processors, whether artifacts associated with injection are present in the first image; determining, using the one or more processors, whether a pose in the first image is suspiciously similar to a pose in a second image; and determining whether a background portion in the first image is suspiciously similar to a background portion in another image, wherein the another image was previously received in association with a prior request, wherein the prior request was associated with different document holder data.

Abstract: A method of providing a refractive prescription includes: receiving a plurality of images from a sensor, the plurality of images captured sequentially using light from an eye of a living being: determining respective values of an image quality metric (IQM) for respective images of the captured plurality of images: selecting a subset of the plurality of images based on the values of the IQM; and determining and outputting to a user a refractive prescription for the eye based on the subset of the plurality of images. Example embodiments can be employed to produce and output better refractive prescriptions by taking into account dynamics of a patient's eye.

Abstract: Open view smart eyewear is combined with a wavefront aberrometer module. The smart eyewear serves as an open view eyewear form factor and house the wavefront aberrometer module among other digital processing components and corresponding software. Alternatively, the wavefront aberrometer module is removably coupled to the smart eyewear. The wavefront aberrometer module calibrates a tunable optical element according to detected optical needs of the user. The wavefront aberrometer module automatically adjusts the wearer-user's effective visual acuity (at least refractive power) viewing through the smart eyewear. The smart eyewear apparatus can also provide clinical-quality optical measurements of wearer-users for electronic communication or transmission to an eye care professional. Alignment of open view smart eyewear, the wavefront aberrometer module, and user's eyes (line of sight) can be facilitated.

Abstract: Clinical-quality eye examinations are provided at locations remote from the physician and outside of a clinical setting. A portable optical device and corresponding software are delivered to the patient's location. The portable optical device is configured for patient use in self-conducting an eye or vision exam and taking optical measurements. As a function of type of optical measurement data or health consideration of the patient, the corresponding software provides uploading and live streaming of the optical measurement data to the physician. The corresponding software is executed during the patient conducting the eye (vision) exam and enables the remotely located physician, to participate in the same via video conference. Alternatively, an artificial intelligence resource operating remotely or locally can provide physician-type guidance and eye health assessments. Alignment of device and patient eyes can be facilitated for remote exams.

Abstract: Disclosed is a method for assessing the transduction efficiency and/or specificity of vectors at single cell level.

Abstract: An apparatus, and corresponding method, for determining a property of an eye includes a housing with a proximal port that receives an eye and also light from the eye. The housing further includes a distal port, and the two ports together form a visual channel providing an open view to enable the eye to see target indicia external to and spaced away from the housing. A wavefront sensor within the housing is configured to receive the light from the eye via the optical path and to measure a wavefront of the light. A determination module determines an objective refractive correction based on the wavefront and predicts a subjective refractive preference of a person having the eye based on the objective refractive correction. Embodiments can be handheld, and binocular, and predict subjective refraction based on demographic and other information.

Abstract: An apparatus, and corresponding method, for determining a refractive property of an eye includes a housing with a port configured to receive an eye and also light from the eye. A tunable lens can be mounted to the housing to apply a variable focal power to the light from the eye and to pass the light along an optical path toward a wavefront sensor within the housing. The wavefront sensor can receive the light via the optical path and measure a wavefront thereof. A determination module can be configured to determine a property of the eye based on the wavefront. Embodiments can be handheld, portable, and open view, while providing objective wavefront aberrometry, subjective phoroptry, and accommodation and presbyoptic evaluation, as well as lensometry functions.

Abstract: Eye prescriptions may be determined by providing a simple, easy to use, portable device with a specially configured targeting light source that aligns the eye, mitigates accommodation, and provides accurate results. Unlike stationary, closed view autorefractors, this device typically is portable, self-usable, relatively inexpensive, enabling more widespread use across the world.

Abstract: An apparatus, and corresponding method, for determining a refractive property of an eye includes a housing with a port configured to receive an eye and also light from the eye. A tunable lens can be mounted to the housing to apply a variable focal power to the light from the eye and to pass the light along an optical path toward a wavefront sensor within the housing. The wavefront sensor can receive the light via the optical path and measure a wavefront thereof. A determination module can be configured to determine a property of the eye based on the wavefront. Embodiments can be handheld, portable, and open view, while providing objective wavefront aberrometry, subjective phoroptry, and accommodation and presbyoptic evaluation, as well as lensometry functions.

Abstract: An apparatus, and corresponding method, for determining a refractive property of an eye includes a housing with a port configured to receive an eye and also light from the eye. A tunable lens can be mounted to the housing to apply a variable focal power to the light from the eye and to pass the light along an optical path toward a wavefront sensor within the housing. The wavefront sensor can receive the light via the optical path and measure a wavefront thereof. A determination module can be configured to determine a property of the eye based on the wavefront. Embodiments can be handheld, portable, and open view, while providing objective wavefront aberrometry, subjective phoroptry, and accommodation and presbyoptic evaluation, as well as lensometry functions.

Abstract: Eye prescriptions may be determined by providing a simple, easy to use, portable device with a specially configured targeting light source that aligns the eye, mitigates accommodation, and provides accurate results. Unlike stationary, closed view autorefractors, this device typically is portable, self-usable, relatively inexpensive, enabling more widespread use across the world.

Abstract: Eye prescriptions may be determined by providing a simple, easy to use, portable device with a specially configured targeting light source that aligns the eye, mitigates accommodation, and provides accurate results. Unlike stationary, closed view autorefractors, this device typically is portable, self-usable, relatively inexpensive, enabling more widespread use across the world.

Abstract: The present invention relates to systems and methods for photometric endoscope imaging. The methods can further include chromoendoscopy and computer aided detection procedures for the imaging of body lumens and cavities.

Abstract: A first image data set of the real-world object is received at a processor where the real-world object was illuminated with substantially uniform illumination. A second image data set of the real-world object is received at the processor where the real-world object was illuminated with substantially structured illumination. A high pass filter is applied to the first-image data set to remove out-of-focus content and retrieve high-frequency in-focus content. The local contrast of the second-image data set is determined producing a low resolution local contrast data set. The local contrast provides a low resolution estimate of the in-focus content in the first-image data set. A low pass filter is applied to the estimated low resolution in-focus data set, thus making its frequency information complementary to the high-frequency in-focus data set. The low and high frequency in-focus data sets are combined to produce an optically-sectioned data set of the real-world object.

Abstract: A first image data set of the real-world object is received at a processor where the real-world object was illuminated with substantially uniform illumination. A second image data set of the real-world object is received at the processor where the real-world object was illuminated with substantially structured illumination. A high pass filter is applied to the first-image data set to remove out-of-focus content and retrieve high-frequency in-focus content. The local contrast of the second-image data set is determined producing a low resolution local contrast data set. The local contrast provides a low resolution estimate of the in-focus content in the first-image data set. A low pass filter is applied to the estimated low resolution in-focus data set, thus making its frequency information complementary to the high-frequency in-focus data set. The low and high frequency in-focus data sets are combined to produce an optically-sectioned data set of the real-world object.