Patents by Inventor Daryl Walter

Daryl Walter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Receptor Antagonists and Their Methods of Use
    Publication number: 20080009541
    Abstract: The present invention relates to novel oxo-prolinamide derivatives of formula (I) which modulate P2X7 receptor function and are capable of antagonizing the effects of ATP at the P2X7 receptor and the use of such compounds or pharmaceutical compositions thereof in the treatment of disorders mediated by the P2X7 receptor, for example pain, inflammation and neurodegeneration.
    Type: Application
    Filed: July 3, 2007
    Publication date: January 10, 2008
    Applicant: GLAXO GROUP LIMITED
    Inventors: Laura Chambers, Robert Gleave, Stefan Senger, Daryl Walter
  • Tricycle indole hydroxyethlamine derivatives and their use in the treatment of alzheimer's disease
    Publication number: 20070073060
    Abstract: The present invention relates to novel hydroxyethylamine compounds having Asp2 (?-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated ?-amyloid levels or ?-amyloid deposits, particularly Alzheimer's disease.
    Type: Application
    Filed: December 9, 2004
    Publication date: March 29, 2007
    Inventors: Emmanuel Demont, Sally Redshaw, David Vesey, Daryl Walter
  • Tricyclic indole derivatives and their use in the treatment of alzheimer's disease
    Publication number: 20060229302
    Abstract: The present invention to novel hydroxyethylamine compounds having Asp2 (?-secretase, BACE1 or Memapsin) inhibitory activit, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated ?-amyloid levels or ?-amyloid deposits, Particularly Alzheimer's disease.
    Type: Application
    Filed: April 21, 2004
    Publication date: October 12, 2006
    Inventors: Emmanuel Demont, Sally Redshaw, Daryl Walter
  • Novel compounds
    Publication number: 20060211740
    Abstract: The present invention relates to novel hydroxyethylamine compounds having Asp2 (?-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated ?-amyloid levels or ?-amyloid deposits, particularly Alzheimer's disease.
    Type: Application
    Filed: March 11, 2004
    Publication date: September 21, 2006
    Inventors: Emmanuel Demont, Sally Redshaw, Daryl Walter
  • Hydroxyethylamine derivatives for the treatment of alzheimer's disease
    Publication number: 20060025459
    Abstract: The present invention relates to novel hydroxyethylamine compounds having Asp2 (?-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated ?-amyloid levels or ?-amyloid deposits, particularly Alzheimer's disease.
    Type: Application
    Filed: December 3, 2003
    Publication date: February 2, 2006
    Inventors: Emmanuel Demont, Andrew Faller, David Macpherson, Peter Milner, Alan Naylor, Sally Redshaw, Steven Stanway, David Vesey, Daryl Walter