Patents by Inventor Dasaradhi Lakkaraju
Dasaradhi Lakkaraju has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240423954Abstract: Compositions of a stabilized chlorthalidone suspension and methods for making a stabilized chlorthalidone suspension include chlorthalidone along with a solubilizing and/or wetting agent, a suspending agent, and a viscosity increasing agent and/or an anti-caking agent, wherein the stabilized chlorthalidone suspension is a uniform dispersion with consistent concentration of chlorthalidone throughout the composition and storage.Type: ApplicationFiled: March 4, 2024Publication date: December 26, 2024Applicant: Nivagen Pharmaceuticals, Inc.Inventors: Govind R. Jagadale, Dasaradhi Lakkaraju, Bala Tripura Sundari Chodavarapu, Niravkumar Prajapati, Anand Shukla, Jay Shukla, Robert Miller, Niravbhai Jayantibhai Patel, Maheshkumar Kalubhai Bhalaria
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Patent number: 12115187Abstract: Ready-to-use (RTU) Sodium Phosphates solutions for phosphorus replacement therapy are presented that include Sodium phosphate with/without sodium chloride at a fixed volume with 1.5 to 15 mmol/100 mL phosphorus, no more than 20 mEq/100 mL Sodium and less than 50 mcg/L aluminum.Type: GrantFiled: May 17, 2024Date of Patent: October 15, 2024Assignee: Nivagen Pharmaceuticals, Inc.Inventors: Niravbhai Jayantibhai Patel, Robert Miller, Maheshkumar Kalubhai Bhalaria, Rucha Abhijit Kelekar, Brijeshkumar B Pandya, Sunil Dnyanu Khandekar, Sudhir Shantarum Jagdale, Dasaradhi Lakkaraju, Jay Shukla
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Patent number: 12102624Abstract: A spray-dried storage stable pantoprazole composition is provided. The pantoprazole composition includes a pantoprazole and an excipient matrix including sodium chloride (NaCl). The pantoprazole is substantially uniformly dispersed in the excipient matrix. A method for forming a storage stable pantoprazole composition is also provided. The method includes combining a bulking agent and water to form a first solution, combining a pantoprazole and the first solution to form a second solution, combining sodium hydroxide and the second solution to form a bulk solution, and removing water from the bulk solution by drying to form the storage stable pantoprazole composition.Type: GrantFiled: August 26, 2021Date of Patent: October 1, 2024Assignee: Nivagen Pharmaceuticals, Inc.Inventors: Brijeshkumar B. Pandya, Govind R. Jagadale, Dasaradhi Lakkaraju, Bala Tripura Sundari Chodavarapu, Anand Shukla, Jwalant Shukla
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Patent number: 11957658Abstract: Compositions of a stabilized chlorthalidone suspension and methods for making a stabilized chlorthalidone suspension include chlorthalidone along with a solubilizing and/or wetting agent, a suspending agent, and a viscosity increasing agent and/or an anti-caking agent, wherein the stabilized chlorthalidone suspension is a uniform dispersion with consistent concentration of chlorthalidone throughout the composition and storage.Type: GrantFiled: May 26, 2021Date of Patent: April 16, 2024Assignee: Nivagen Pharmaceuticals, Inc.Inventors: Govind R. Jagadale, Dasaradhi Lakkaraju, Bala Tripura Sundari Chodavarapu, Niravkumar Prajapati, Anand Shukla, Jay Shukla
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Patent number: 11925661Abstract: Ready-to-use (RTU) potassium phosphates solutions for phosphorus replacement therapy are presented that include potassium phosphate and sodium chloride at a fixed volume with 1.5 to 15 mmol/100 mL phosphorus, no more than 22 mEq/100 mL potassium and less than 50 mcg/L aluminum.Type: GrantFiled: September 5, 2023Date of Patent: March 12, 2024Assignee: Nivagen Pharmaceuticals, Inc.Inventors: Brijeshkumar B. Pandya, Govind R. Jagadale, Dasaradhi Lakkaraju, Bala Tripura Sundari Chodavarapu, Anand Shukla, Jwalant Shukla
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Patent number: 11878076Abstract: A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenylethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.Type: GrantFiled: January 24, 2023Date of Patent: January 23, 2024Assignee: NIVAGEN PHARMACEUTICALS, INC.Inventors: Bala Tripura Sundari Chodavarapu, Thirupathi Mangali, Jay Shukla, Anand Shukla, Dasaradhi Lakkaraju
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Publication number: 20230405045Abstract: Ready-to-use (RTU) potassium phosphates solutions for phosphorus replacement therapy are presented that include potassium phosphate and sodium chloride at a fixed volume with 1.5 to 15 mmol/100 mL phosphorus, no more than 22 mEq/100 mL potassium and less than 50 mcg/L aluminum.Type: ApplicationFiled: September 5, 2023Publication date: December 21, 2023Applicant: Nivagen Pharmaceuticals, Inc.Inventors: Brijeshkumar B. Pandya, Govind R. Jagadale, Dasaradhi Lakkaraju, Bala Tripura Sundari Chodavarapu, Anand Shukla, Jwalant Shukla
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Patent number: 11813291Abstract: A ready-to-use (RTU) potassium phosphates in sodium chloride solution for phosphorus replacement therapy includes potassium phosphate and sodium chloride at a fixed volume with 15 mmol/100 mL phosphorus and 22 mEq/100 mL potassium and less than 50 mcg/L aluminum.Type: GrantFiled: October 12, 2021Date of Patent: November 14, 2023Assignee: NIVAGEN PHARMACEUTICALS, INC.Inventors: Brijeshkumar B. Pandya, Govind R. Jagadale, Dasaradhi Lakkaraju, Bala Tripura Sundari Chodavarapu, Anand Shukla, Jwalant Shukla
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Patent number: 11672823Abstract: Described is an aqueous calcium gluconate solution formulated without calcium saccharate, which can be stored in a flexible plastic bag and can be terminally sterilized.Type: GrantFiled: July 22, 2022Date of Patent: June 13, 2023Assignee: Nivagen Pharmaceuticals, Inc.Inventors: Thirupathi Mangali, Bala Tripura Sundari Chodavarapu, Anand Shukla, Jay Shukla, Dasaradhi Lakkaraju
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Publication number: 20230157959Abstract: A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenylethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.Type: ApplicationFiled: January 24, 2023Publication date: May 25, 2023Applicant: Nivagen Pharmaceuticals, Inc.Inventors: Bala Tripura Sundari Chodavarapu, Thirupathi Mangali, Jay Shukla, Anand Shukla, Dasaradhi Lakkaraju
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Publication number: 20230043597Abstract: Described is an aqueous calcium gluconate solution formulated without calcium saccharate, which can be stored in a flexible plastic bag and can be terminally sterilized.Type: ApplicationFiled: July 22, 2022Publication date: February 9, 2023Applicant: Nivagen Pharmaceuticals, Inc.Inventors: Thirupathi Mangali, Bala Tripura Sundari Chodavarapu, Anand Shukla, Jay Shukla, Dasaradhi Lakkaraju
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Publication number: 20220354794Abstract: A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenyl ethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.Type: ApplicationFiled: June 30, 2022Publication date: November 10, 2022Applicant: Nivagen Pharmaceuticals, Inc.Inventors: Bala Tripura Sundari Chodavarapu, Thirupathi Mangali, Jay Shukla, Anand Shukla, Dasaradhi Lakkaraju
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Patent number: 11406598Abstract: A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenylethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.Type: GrantFiled: September 18, 2020Date of Patent: August 9, 2022Assignee: NIVAGEN PHARMACEUTICALS, INC.Inventors: Bala Tripura Sundari Chodavarapu, Thirupathi Mangali, Jay Shukla, Anand Shukla, Dasaradhi Lakkaraju
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Publication number: 20220110969Abstract: A ready-to-use (RTU) potassium phosphates in sodium chloride solution for phosphorus replacement therapy includes potassium phosphate and sodium chloride at a fixed volume with 15 mmol/100 mL phosphorus and 22 mEq/100 mL potassium and less than 50 mcg/L aluminum.Type: ApplicationFiled: October 12, 2021Publication date: April 14, 2022Applicant: Nivagen Pharmaceuticals, Inc.Inventors: Brijeshkumar B. Pandya, Govind R. Jagadale, Dasaradhi Lakkaraju, Bala Tripura Sundari Chodavarapu, Anand Shukla, Jwalant Shukla
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Publication number: 20220062253Abstract: A spray-dried storage stable pantoprazole composition is provided. The pantoprazole composition includes a pantoprazole and an excipient matrix including sodium chloride (NaCl). The pantoprazole is substantially uniformly dispersed in the excipient matrix. A method for forming a storage stable pantoprazole composition is also provided. The method includes combining a bulking agent and water to form a first solution, combining a pantoprazole and the first solution to form a second solution, combining sodium hydroxide and the second solution to form a bulk solution, and removing water from the bulk solution by drying to form the storage stable pantoprazole composition.Type: ApplicationFiled: August 26, 2021Publication date: March 3, 2022Applicant: NIVAGEN PHARMACEUTICALS, INC.Inventors: Brijeshkumar B. Pandya, Govind R. Jagadale, Dasaradhi Lakkaraju, Bala Tripura Sundari Chodavarapu, Anand Shukla, Jwalant Shukla
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Publication number: 20210369673Abstract: Compositions of a stabilized chlorthalidone suspension and methods for making a stabilized chlorthalidone suspension include chlorthalidone along with a solubilizing and/or wetting agent, a suspending agent, and a viscosity increasing agent and/or an anti-caking agent, wherein the stabilized chlorthalidone suspension is a uniform dispersion with consistent concentration of chlorthalidone throughout the composition and storage.Type: ApplicationFiled: May 26, 2021Publication date: December 2, 2021Applicant: Nivagen Pharmaceuticals, Inc.Inventors: Govind R. Jagadale, Dasaradhi Lakkaraju, Bala Tripura Sundari Chodavarapu, Niravkumar Prajapati, Anand Shukla, Jay Shukla
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Publication number: 20210085608Abstract: A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenylethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.Type: ApplicationFiled: September 18, 2020Publication date: March 25, 2021Applicant: Nivagen Pharmaceuticals, Inc.Inventors: Bala Tripura Sundari Chodavarapu, Thirupathi Mangali, Jay Shukla, Anand Shukla, Dasaradhi Lakkaraju
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Publication number: 20100330158Abstract: The present invention provides a composition and prodrug for targeted drug delivery to the central nervous system of a patient. The inventive composition and prodrug include a pharmaceutically acceptable active agent and at least one protein selected from the group consisting of a fimbrial adhesin protein, a membrane protein, and combinations thereof. The inventive compositions and prodrugs of the present invention selectively target the blood-brain barrier and deliver hydrophilic and lipophilic active agents of varying sizes to the central nervous system.Type: ApplicationFiled: March 26, 2010Publication date: December 30, 2010Applicant: InnoPharma, LLCInventors: Vishal Soni, Kanaiyalal R. Patel, Dasaradhi Lakkaraju, Navneet Puri